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pro vyhledávání: '"Constantin S, Tamvakopoulos"'
Autor:
Judith E, Fenyk-Melody, Xiaolan, Shen, Qianping, Peng, William, Pikounis, Lawrence, Colwell, James, Pivnichny, Lynn C, Anderson, Constantin S, Tamvakopoulos
Publikováno v:
Comparative medicine. 54(4)
In the process of drug discovery, brain and plasma measurements of new chemical entities in rodents are of interest, particularly when the target receptors are in the brain. Brain-to-plasma ratios (B/P) obtained from a rodent pharmacokinetic assay ar