Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Constantin Mamat"'
Autor:
Santiago Andrés Brühlmann, Martin Walther, Magdalena Kerstin Blei, Constantin Mamat, Klaus Kopka, Robert Freudenberg, Martin Kreller
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-22 (2024)
Abstract Background In recent years, targeted alpha therapy has gained importance in the clinics, and in particular, the alpha-emitter 225Ac plays a fundamental role in this clinical development. Nevertheless, depending on the chelating system no rea
Externí odkaz:
https://doaj.org/article/77ffd4f08c9b45cc8d911bdb6fedb0e9
Autor:
Matthias Miederer, Martina Benešová-Schäfer, Constantin Mamat, David Kästner, Marc Pretze, Enrico Michler, Claudia Brogsitter, Jörg Kotzerke, Klaus Kopka, David A. Scheinberg, Michael R. McDevitt
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 76 (2024)
The use of radionuclides for targeted endoradiotherapy is a rapidly growing field in oncology. In particular, the focus on the biological effects of different radiation qualities is an important factor in understanding and implementing new therapies.
Externí odkaz:
https://doaj.org/article/25291905b7a14e40b287668ad107995a
Publikováno v:
ACS Omega, Vol 5, Iss 27, Pp 16318-16331 (2020)
Externí odkaz:
https://doaj.org/article/847111b719b84cc493b877529ccb5cfc
Autor:
Santiago Andrés Brühlmann, Martin Kreller, Hans-Jürgen Pietzsch, Klaus Kopka, Constantin Mamat, Martin Walther, Falco Reissig
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1167 (2022)
Targeted Alpha Therapy is a research field of highest interest in specialized radionuclide therapy. Over the last decades, several alpha-emitting radionuclides have entered and left research topics towards their clinical translation. Especially, 225A
Externí odkaz:
https://doaj.org/article/e1bd40fef1c94cd9bfea8361bca86f00
Publikováno v:
Molecules, Vol 27, Iss 5, p 1478 (2022)
Two sets of functionalised calix[4]arenes, either with a 1,3-crown ether bridge or with an open-chain oligo ether moiety in 1,3-position were prepared and further equipped with additional deprotonisable sulfonamide groups to establish chelating syste
Externí odkaz:
https://doaj.org/article/d0bfa7d3689740c3b78de28a6c17d8df
Publikováno v:
Molecules, Vol 26, Iss 21, p 6629 (2021)
The traceless Staudinger ligation with its two variants is a powerful biorthogonal conjugation method not only for the connection of biomolecules, but also for the introduction of fluorescence- or radiolabels under mild reaction conditions. Herein, t
Externí odkaz:
https://doaj.org/article/465b5f80fc874b51b4d614c57761cea9
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2478-2489 (2016)
Novel, functionalized piperazine derivatives were successfully synthesized and fully characterized by 1H/13C/19F NMR, MS, elemental analysis and lipophilicity. All piperazine compounds occur as conformers resulting from the partial amide double bond.
Externí odkaz:
https://doaj.org/article/7ecd7bc260654723acf7fc9faa033376
Autor:
Falco Reissig, David Bauer, Martin Ullrich, Martin Kreller, Jens Pietzsch, Constantin Mamat, Klaus Kopka, Hans-Jürgen Pietzsch, Martin Walther
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 272 (2020)
Barium-131 is a single photon emission computed tomography (SPECT)-compatible radionuclide for nuclear medicine and a promising diagnostic match for radium-223/-224. Herein, we report on the sufficient production route 133Cs(p,3n)131Ba by using 27.5
Externí odkaz:
https://doaj.org/article/d47137eec1fc4101b331b6b8c56d1e9f
Autor:
Manuela Kuchar, Constantin Mamat
Publikováno v:
Molecules, Vol 20, Iss 9, Pp 16186-16220 (2015)
The majority of pharmaceuticals and other organic compounds incorporating radiotracers that are considered foreign to the body undergo metabolic changes in vivo. Metabolic degradation of these drugs is commonly caused by a system of enzymes of low su
Externí odkaz:
https://doaj.org/article/8bbe3c394a2443909eda03853007a82b
Autor:
Constantin Mamat, Martin Köckerling
Publikováno v:
Crystals, Vol 5, Iss 1, Pp 9-13 (2014)
The crystal and molecular structure of 2-(diphenylphosphano)phenyl benzoate borane adduct are reported. The title compound crystallizes from a petroleum ether/ethyl acetate mixture in the triclinic space group P with two molecules in the unit cell. T
Externí odkaz:
https://doaj.org/article/ecd8d9adc12d406d9c113fe52977ae9b