Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Constantin GEORGESCU"'
Autor:
Lorena Deleanu, Constantin Georgescu, George Cătălin Cristea, Traian Florian Ionescu, Guglea Dionis, George Ghiocel Ojoc, Dumitru Dima, Iulia Paduraru
Publikováno v:
Tribology in Industry, Vol 46, Iss 3, Pp 398-417 (2024)
This paper presents an analysis of standards applied in tribology, especially concerning materials, test methods and failures of machine components, related to exploitation under load and motion. By the help of their own research and based on open li
Externí odkaz:
https://doaj.org/article/d1699e98600c4a14b4afe31a7ad5bc55
Autor:
Lorena Deleanu, Alina Cantaragiu Ceoromila, Constantin Georgescu, Mihail Botan, George Ghiocel Ojoc, Ioana Gabriela Chiracu
Publikováno v:
Tribology in Industry, Vol 46, Iss 3, Pp 447-457 (2024)
The investigation of a tribosystem failure is important in establishing its causes with the highest probability. This paper proposes a discussion on particular aspects of failure in polymeric composites sliding against steel in dry regime. At micro l
Externí odkaz:
https://doaj.org/article/58cad406944f4e8aa303755d2028fced
Autor:
Shylesh Bhaskaran, Katarzyna M. Piekarz, Jacob Brown, Brian Yang, Sarah R. Ocañas, Jonathan D. Wren, Constantin Georgescu, Christopher Bottoms, Ashley Murphy, Jessica Thomason, Debra Saunders, Nataliya Smith, Rheal Towner, Holly Van Remmen
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Our study investigated the therapeutic potential of OKN-007 in the SOD1 G93A mouse model of amyotrophic lateral sclerosis (ALS). The impact of OKN-007, known for its antioxidant, anti-inflammatory, and neuroprotective properties, was tested at two do
Externí odkaz:
https://doaj.org/article/0e640ce65630411f9790072628df78b8
Autor:
Dimitrios Pollalis, Gopa Kumar Gopinadhan Nair, Justin Leung, Clarisa Marie Bloemhof, Jeffrey K. Bailey, Britney O. Pennington, Kaitlin R. Kelly, Amir I. Khan, Ashley K. Yeh, Kartik S. Sundaram, Dennis O. Clegg, Chen‐Ching Peng, Liya Xu, Constantin Georgescu, Jonathan D. Wren, Sun Young Lee
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract Retinal pigment epithelial (RPE) cells are exclusive to the retina, critically multifunctional in maintaining the visual functions and health of photoreceptors and the retina. Despite their vital functions throughout lifetime, RPE cells lack
Externí odkaz:
https://doaj.org/article/4be1ebe138c34e68b67d9407d4963b56
Autor:
Dionis GUGLEA, George Catalin CRISTEA, Lorena DELEANU, Traian Florian IONESCU, George Ghiocel OJOC, Dumitru DIMA, Constantin GEORGESCU
Publikováno v:
INCAS Bulletin, Vol 15, Iss 4, Pp 137-148 (2023)
This paper presents an analysis based on experimental data for pointing out the behavior of rapeseed oil when it is additivated with a modifier of friction and wear, the nano hexagonal Boron nitride. All tests are done on a four-ball machine, in mild
Externí odkaz:
https://doaj.org/article/b9f184d23ec74033b68746c82d2fd6b6
Autor:
Joshua M. Corbin, Constantin Georgescu, Lin Wang, Jonathan D. Wren, Magdalena Bieniasz, Chao Xu, Adam S. Asch, Maria J. Ruiz Echevarría
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 257-272 (2023)
Blocking androgen receptor signaling is the mainstay of therapy for advanced prostate cancer (PCa). However, acquired resistance to single agents targeting this pathway results in the development of lethal castration-resistant PCa. Combination therap
Externí odkaz:
https://doaj.org/article/41fabf28d4364d8697b56a2f8a9cd7e7
Autor:
Mihnea P. Dragomir, Enrique Fuentes-Mattei, Melanie Winkle, Keishi Okubo, Recep Bayraktar, Erik Knutsen, Aiham Qdaisat, Meng Chen, Yongfeng Li, Masayoshi Shimizu, Lan Pang, Kevin Liu, Xiuping Liu, Simone Anfossi, Huanyu Zhang, Ines Koch, Anh M. Tran, Swati Mohapatra, Anh Ton, Mecit Kaplan, Matthew W. Anderson, Spencer J. Rothfuss, Robert Silasi, Ravi S. Keshari, Manuela Ferracin, Cristina Ivan, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Constantin Georgescu, Pinaki P. Banerjee, Rafet Basar, Ziyi Li, David Horst, Catalin Vasilescu, Maria Teresa S. Bertilaccio, Katayoun Rezvani, Florea Lupu, Sai-Ching Yeung, George A. Calin
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)
Sepsis remains a leading cause of death for humans and currently has no pathogenesis-specific therapy. Hampered progress is partly due to a lack of insight into deep mechanistic processes. In the past decade, deciphering the functions of small noncod
Externí odkaz:
https://doaj.org/article/d4033ceefb364ffba4d3f09a718cc569
Autor:
Xiavan Renaldo Roopnarinesingh, Hunter Porter, Cory Giles, Chase Brown, Constantin Georgescu, Jonathan Wren
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1404-1418 (2022)
Background Transcriptional correlation networks derived from publicly available gene expression microarrays have been previously shown to be predictive of known gene functions, but less is known about the predictive capacity of correlated DNA methyla
Externí odkaz:
https://doaj.org/article/d65d3e3b0f64464eaa14f84f37dfbabb
Autor:
Katarzyna Zyla-Jackson, Dorothy A. Walton, Kendra S. Plafker, Susan Kovats, Constantin Georgescu, Richard S. Brush, Madison Tytanic, Martin-Paul Agbaga, Scott M. Plafker
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionFive to eight percent of the world population currently suffers from at least one autoimmune disorder. Despite multiple immune modulatory therapies for autoimmune demyelinating diseases of the central nervous system, these treatments can
Externí odkaz:
https://doaj.org/article/277427e44b8545229135fd962009e462
Autor:
Jacob L. Brown, Fredrick F. Peelor, III, Constantin Georgescu, Jonathan D. Wren, Michael Kinter, Victoria J. Tyrrell, Valerie B. O'Donnell, Benjamin F. Miller, Holly Van Remmen
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102518- (2022)
Loss of innervation is a key driver of age associated muscle atrophy and weakness (sarcopenia). Our laboratory has previously shown that denervation induced atrophy is associated with the generation of mitochondrial hydroperoxides and lipid mediators
Externí odkaz:
https://doaj.org/article/3239a27805754d5683dbbbba59aaf6a0