Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Constantin, Schwab"'
Autor:
Ahmed Elwakiel, Dheerendra Gupta, Rajiv Rana, Jayakumar Manoharan, Moh’d Mohanad Al-Dabet, Saira Ambreen, Sameen Fatima, Silke Zimmermann, Akash Mathew, Zhiyang Li, Kunal Singh, Anubhuti Gupta, Surinder Pal, Alba Sulaj, Stefan Kopf, Constantin Schwab, Ronny Baber, Robert Geffers, Tom Götze, Bekas Alo, Christina Lamers, Paul Kluge, Georg Kuenze, Shrey Kohli, Thomas Renné, Khurrum Shahzad, Berend Isermann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Coagulation factor XII (FXII) conveys various functions as an active protease that promotes thrombosis and inflammation, and as a zymogen via surface receptors like urokinase-type plasminogen activator receptor (uPAR). While plasma levels of
Externí odkaz:
https://doaj.org/article/2ce97d19ca754507a003d6b16a5ab8c0
Autor:
Ann-Kathrin Huber, Adam Kaczorowski, Felix Schneider, Sarah Böning, Magdalena Görtz, David Langhoff, Constantin Schwab, Albrecht Stenzinger, Markus Hohenfellner, Anette Duensing, Stefan Duensing
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Prostate cancer is characterized by a high degree of intratumoral heterogeneity. However, little is known about the spatial distribution of cancer cells with respect to specific functional characteristics and the formation of spatial niches.
Externí odkaz:
https://doaj.org/article/6f2323e622bd4340a97f4f1e189d9949
Autor:
Philippa Lantwin, Adam Kaczorowski, Cathleen Nientiedt, Constantin Schwab, Martina Kirchner, Viktoria Schütz, Magdalena Görtz, Markus Hohenfellner, Anette Duensing, Albrecht Stenzinger, Stefan Duensing
Publikováno v:
Onco, Vol 4, Iss 2, Pp 56-67 (2024)
Introduction: DNA damage repair gene deficiency defines a subgroup of prostate cancer patients with early metastatic progression and unfavorable disease outcome. Whether deficiency in DNA damage repair genes directly promotes metastatic dissemination
Externí odkaz:
https://doaj.org/article/9f17468612fa46e4819be81e9d632d17
Autor:
Eszter Levai, Iva Marinovic, Maria Bartosova, Conghui Zhang, Betti Schaefer, Hanna Jenei, Zhiwei Du, Dorota Drozdz, Günter Klaus, Klaus Arbeiter, Philipp Romero, Vedat Schwenger, Constantin Schwab, Attila J. Szabo, Sotirios G. Zarogiannis, Claus Peter Schmitt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Next to the skin, the peritoneum is the largest human organ, essentially involved in abdominal health and disease states, but information on peritoneal paracellular tight junctions and transcellular channels and transporters relative to peri
Externí odkaz:
https://doaj.org/article/69950bb762e74cee9493f0850e9d668b
Autor:
Philipp Romero, Astrid Burger, Erica Wennberg, Stefanie Schmitteckert, Stefan Holland-Cunz, Constantin Schwab, Patrick Günther
Publikováno v:
Children, Vol 11, Iss 4, p 428 (2024)
Introduction: Hirschsprung disease (HD) manifests as a developmental anomaly affecting the enteric nervous system, where there is an absence of ganglion cells in the lower part of the intestine. This deficiency leads to functional blockages within th
Externí odkaz:
https://doaj.org/article/a800a25b426a4a939546ebe92050d432
Autor:
Philipp Reimold, Georgi Tosev, Adam Kaczorowski, Jana Friedhoff, Constantin Schwab, Viktoria Schütz, Magdalena Görtz, Niklas Panzer, Martina Heller, Cem Aksoy, Ruth Himmelsbach, Thomas Walle, Stefanie Zschäbitz, Dirk Jäger, Anette Duensing, Albrecht Stenzinger, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Diagnostics, Vol 14, Iss 7, p 741 (2024)
Background: Renal cell carcinoma (RCC) is among the most lethal urologic malignancies once metastatic. Current treatment approaches for metastatic RCC (mRCC) involve immune checkpoint inhibitors (ICIs) that target the PD-L1/PD-1 axis. High PD-L1 expr
Externí odkaz:
https://doaj.org/article/024657d17a2c4da0b88ebf9657dd40fd
Autor:
Louise Benning, Christian Morath, Annette Fink, Markus Rudek, Claudius Speer, Florian Kälble, Christian Nusshag, Jörg Beimler, Constantin Schwab, Rüdiger Waldherr, Martin Zeier, Caner Süsal, Thuong Hien Tran
Publikováno v:
Transplant International, Vol 36 (2023)
Donor-derived cell-free DNA (dd-cfDNA) identifies allograft injury and discriminates active rejection from no rejection. In this prospective study, 106 kidney transplant recipients with 108 clinically indicated biopsies were enrolled at Heidelberg Un
Externí odkaz:
https://doaj.org/article/dd27de4fe00d46a19c12bf2a47c50f5f
Autor:
Michael Menzel, Volker Endris, Constantin Schwab, Klaus Kluck, Olaf Neumann, Susanne Beck, Markus Ball, Christian Schaaf, Stefan Fröhling, Peter Lichtner, Peter Schirmacher, Daniel Kazdal, Albrecht Stenzinger, Jan Budczies
Publikováno v:
Translational Oncology, Vol 35, Iss , Pp 101706- (2023)
Homologous recombination deficiency (HRD) is a predictive marker for response to poly (ADP-ribose) polymerase inhibitors (PARPi) in ovarian carcinoma. HRD scores have entered routine diagnostics, but the influence of algorithms, parameters and confou
Externí odkaz:
https://doaj.org/article/4e88daf2b11f4936876a9802128bc881
Autor:
Simone Feurstein, Julian Zoller, Constantin Schwab, Sarah Schreiner, Heiko Mundt, Iris Breitkreutz, Brigitte Schneider, Jörg Beimler, Martin Zeier, Rüdiger Waldherr, Stefan Gröschel, Carsten Müller‐Tidow, Stefan O. Schönland, Ute Hegenbart
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1377-1380 (2022)
Abstract Due to differences in the protein folding mechanisms, it is exceedingly rare for amyloid light chain (AL) amyloidosis and monoclonal gammopathy of renal significance (MGRS) to coexist. We herein report the first case of concurrent AL amyloid
Externí odkaz:
https://doaj.org/article/762da7cf1a1d491ba281f9f797e23edf
Autor:
Matthias Schaier, Christian Morath, Lei Wang, Christian Kleist, Gerhard Opelz, Thuong Hien Tran, Sabine Scherer, Lien Pham, Naruemol Ekpoom, Caner Süsal, Gerald Ponath, Florian Kälble, Claudius Speer, Louise Benning, Christian Nusshag, Christoph F. Mahler, Luiza Pego da Silva, Claudia Sommerer, Angela Hückelhoven-Krauss, David Czock, Arianeb Mehrabi, Constantin Schwab, Rüdiger Waldherr, Paul Schnitzler, Uta Merle, Vedat Schwenger, Markus Krautter, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Anna-Isabelle Kälsch, Bernhard K. Krämer, Georg A. Böhmig, Carsten Müller-Tidow, Jochen Reiser, Martin Zeier, Michael Schmitt, Peter Terness, Anita Schmitt, Volker Daniel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe administration of modified immune cells (MIC) before kidney transplantation led to specific immunosuppression against the allogeneic donor and a significant increase in regulatory B lymphocytes. We wondered how this approach affected th
Externí odkaz:
https://doaj.org/article/e8a3a583d0ee42d7b2d399e91afea0aa