Zobrazeno 1 - 10
of 251
pro vyhledávání: '"Constantin, Bouras"'
Autor:
Geneviève Leuba, Claude Walzer, André Vernay, Béatrice Carnal, Rudolf Kraftsik, Françoise Piotton, Pascale Marin, Constantin Bouras, Armand Savioz
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 3, Pp 408-419 (2008)
In order to understand how plasticity is related to neurodegeneration, we studied synaptic proteins with quantitative immunohistochemistry in the entorhinal cortex from Alzheimer patients and age-matched controls. We observed a significant decrease i
Externí odkaz:
https://doaj.org/article/bb9e8871c60e4f1b9124867e34d1a440
Autor:
Anouk Imhof, Yves Charnay, Philippe G. Vallet, Bruce Aronow, Eniko Kovari, Lars E. French, Constantin Bouras, Panteleimon Giannakopoulos
Publikováno v:
Neurobiology of Disease, Vol 22, Iss 2, Pp 274-283 (2006)
Clusterin is a glycoprotein highly expressed in response to tissue injury. Using clusterin-deficient (Clu−/−) mice, we investigated the role of clusterin after permanent middle cerebral artery occlusion (MCAO). In wild-type (WT) mice, clusterin m
Externí odkaz:
https://doaj.org/article/00599607dbe74170b27bc87e4cf05a51
Autor:
Armand Savioz, Beat M Riederer, Peter Heutink, Patrizia Rizzu, Markus Tolnay, Enikö Kövari, Alphonse Probst, I.rène M Riederer, Constantin Bouras, Geneviève Leuba
Publikováno v:
Neurobiology of Disease, Vol 12, Iss 1, Pp 46-55 (2003)
A Swiss frontotemporal dementia (FTD) kindred with extrapyramidal-like features and without motor neuron disease shows a brain pathology with ubiquitin-positive but tau-negative inclusions. Tau and neurofilament modifications are now studied here in
Externí odkaz:
https://doaj.org/article/e0eba6565e9a4b458a18258192eb9350
Publikováno v:
Scopus-Elsevier
Ubiquitin-positive tau-negative inclusions were initially described in the rare form of frontotemporal dementia (FTD) associated with motor neuron disease. However, recent studies have indicated that these inclusions are also present in typical FTD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff143d42dc2ff11a07a9e22d4f18f7d
http://doc.rero.ch/record/315928/files/401_2004_Article_881.pdf
http://doc.rero.ch/record/315928/files/401_2004_Article_881.pdf
The presence of Lewy bodies (LB) in autonomic structures of the central and peripheral nervous system in Parkinson's disease (PD) is well known and could explain clinical signs of pure autonomic failure (PAF) or dysphagia, frequently associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1150fc897e544ef5133be5998bac3a6d
http://doc.rero.ch/record/317457/files/401_2007_Article_233.pdf
http://doc.rero.ch/record/317457/files/401_2007_Article_233.pdf
Autor:
Ion Beratis, Judit Horvath, Eniko Veronika Kovari, François Herrmann, Sokratis G. Papageorgiou, Constantin Bouras
Publikováno v:
Journal of Neurology, Vol. 263, No 4 (2016) pp. 657-664
Recent accumulated evidence indicates that episodic memory impairments could be part of the initial clinical expression of frontotemporal dementia (FTD). An early study on this issue was carried out by Constantinidis and colleagues in 1974, but it wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::329d9fe4c54e0abd52316591b9272685
https://doi.org/10.1007/s00415-015-8019-6
https://doi.org/10.1007/s00415-015-8019-6
Autor:
Ezio Giacobini, Armand Savioz, Eniko Veronika Kovari, Panteleimon Giannakopoulos, Constantin Bouras, François Herrmann, William L. Klein
Publikováno v:
Neurodegenerative Diseases, Vol. 16, No 5-6 (2016) pp. 398-406
Background/Aims: Investigations of Aβ oligomers in neuropathologically confirmed Alzheimer's disease (AD) are still scarce. We report neurohistopathological and biochemical analyses using antibodies against tau and amyloid β (Aβ) pathology. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057d4b27ebec3765703c2a7352c32160
https://doi.org/10.1159/000446283
https://doi.org/10.1159/000446283
Autor:
Sarah Gourmaud, Jacques Hugon, Clarisse Pace, Constantin Bouras, Françoise Gray, Julien Dumurgier, Jean-Louis Laplanche, Eliane F. Meurs, Claire Paquet, François Mouton-Liger
Publikováno v:
Journal of Psychiatry and Neuroscience. 40:151-161
Background: Alzheimer disease is characterized by cognitive decline, senile plaques of β-amyloid (Aβ) peptides, neurofibrillary tangles composed of hyperphosphorylated τ proteins and neuronal loss. Aβ and τ are useful markers in the cerebrospina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4241fa744aa5e58a697dc4fe77a2d275
https://doi.org/10.1503/jpn.140062
https://doi.org/10.1503/jpn.140062
Autor:
Patrick R. Hof, Constantin Bouras, Eniko Veronika Kovari, Aikaterini Xekardaki, Stergios Tsartsalis
Publikováno v:
Neurobiology of Aging, Vol. 62 (2018) pp. 34-44
Amyloid deposits and tau-immunoreactive neurofibrillary tangles, together with neuronal and synaptic loss, are the neuropathological hallmarks of Alzheimer's disease (AD). Both proteins are present in the normal brain during aging. However, the tempo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee4ecfd38567ad593f910973087175
https://archive-ouverte.unige.ch/unige:105123
https://archive-ouverte.unige.ch/unige:105123
Autor:
Patrick Fugistier, Philippe G. Vallet, Geneviève Leuba, Françoise Piotton, Armand Savioz, Pascale Marin, Constantin Bouras
Publikováno v:
Neurobiology of Aging, Vol. 35, No 2 (2014) pp. 322-330
Superficial layers I to III of the human cerebral cortex are more vulnerable toward Aβ peptides than deep layers V to VI in aging. Three models of layers were used to investigate this pattern of frailty. First, primary neurons from E14 and E17 embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::802be729579121c047af5e21f8ec8460
https://doi.org/10.1016/j.neurobiolaging.2013.08.005
https://doi.org/10.1016/j.neurobiolaging.2013.08.005