Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Constantijn J M Halkes"'
Autor:
E. Onur Karakaslar, Jeppe F. Severens, Elena Sánchez-López, Peter A. van Veelen, Mihaela Zlei, Jacques J. M. van Dongen, Annemarie M. Otte, Constantijn J. M. Halkes, Peter van Balen, Hendrik Veelken, Marcel J. T. Reinders, Marieke Griffioen, Erik B. van den Akker
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract The diagnostic spectrum for AML patients is increasingly based on genetic abnormalities due to their prognostic and predictive value. However, information on the AML blast phenotype regarding their maturational arrest has started to regain i
Externí odkaz:
https://doaj.org/article/21d4317eb7704a259707b43c5a1bffc6
Autor:
Mark G J de Boer, Hetty Jolink, Constantijn J M Halkes, Pim L J van der Heiden, Dennis Kremer, J H Frederik Falkenburg, Esther van de Vosse, Jaap T van Dissel
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18403 (2011)
The innate immune system plays a pivotal role in the primary defence against invasive fungal infection. Genetic variation in genes that regulate this response, initiated by pulmonary macrophages, may influence susceptibility to invasive aspergillosis
Externí odkaz:
https://doaj.org/article/fdfdd29249ce461890639c6880881c68
Autor:
Eva A. S. Koster, Peter A. von dem Borne, Peter van Balen, Erik W. A. Marijt, Jennifer M. L. Tjon, Tjeerd J. F. Snijders, Daniëlle van Lammeren, Hendrik Veelken, J. H. Frederik Falkenburg, Constantijn J. M. Halkes, Liesbeth C. de Wreede
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionUnmodified donor lymphocyte infusions (DLI) after allogeneic stem cell transplantation (alloSCT) can boost the beneficial Graft-versus-Leukemia (GvL) effect but may also induce severe Graft-versus-Host-Disease (GvHD). To improve the balan
Externí odkaz:
https://doaj.org/article/f91495ebee1a4669a0b7b64a4d0daa90
Autor:
Eva A. S. Koster, Edouard F. Bonneville, Peter A. von dem Borne, Peter van Balen, Erik W. A. Marijt, Jennifer M. L. Tjon, Tjeerd J. F. Snijders, Daniëlle van Lammeren, Hendrik Veelken, Hein Putter, J. H. Frederik Falkenburg, Constantijn J. M. Halkes, Liesbeth C. de Wreede
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Alloreactive donor-derived T-cells play a pivotal role in alloimmune responses after allogeneic hematopoietic stem cell transplantation (alloSCT); both in the relapse-preventing Graft-versus-Leukemia (GvL) effect and the potentially lethal complicati
Externí odkaz:
https://doaj.org/article/80d6d14acc53406c9e680ff7959ef80a
Autor:
Maddalena Noviello, Francesco Manfredi, Eliana Ruggiero, Tommaso Perini, Giacomo Oliveira, Filippo Cortesi, Pantaleo De Simone, Cristina Toffalori, Valentina Gambacorta, Raffaella Greco, Jacopo Peccatori, Monica Casucci, Giulia Casorati, Paolo Dellabona, Masahiro Onozawa, Takanori Teshima, Marieke Griffioen, Constantijn J. M. Halkes, J. H. F. Falkenburg, Friedrich Stölzel, Heidi Altmann, Martin Bornhäuser, Miguel Waterhouse, Robert Zeiser, Jürgen Finke, Nicoletta Cieri, Attilio Bondanza, Luca Vago, Fabio Ciceri, Chiara Bonini
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Allogeneic hematopoietic cell transplantation is the standard treatment of acute myeloid leukemia, but many patients relapse. Here the authors show increased markers of exhaustion and cancer antigen specificity within bone marrow-residing memory T ce
Externí odkaz:
https://doaj.org/article/2409f0f6f05e4b0d801cc71746493996
Publikováno v:
Cells, Vol 10, Iss 11, p 2905 (2021)
Idiopathic acquired aplastic anemia can be successfully treated with Anti Thymocyte Globulin (ATG)-based immune suppressive therapy and is therefore considered a T cell-mediated auto immune disease. Based on this finding, several other forms of idiop
Externí odkaz:
https://doaj.org/article/dfced9c7352f494ba3359605390d7ce9
Autor:
Peter van Balen, Cornelis A. M. van Bergen, Simone A. P. van Luxemburg-Heijs, Wendy de Klerk, Esther H. M. van Egmond, Sabrina A. J. Veld, Constantijn J. M. Halkes, Jaap-Jan Zwaginga, Marieke Griffioen, Inge Jedema, J. H. Frederik Falkenburg
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Under non-inflammatory conditions HLA class II is predominantly expressed on hematopoietic cells. Therefore, donor CD4 T-cells after allogeneic stem cell transplantation (alloSCT) may mediate graft-vs.-leukemia reactivity without graft-vs.-host disea
Externí odkaz:
https://doaj.org/article/3e852966f115490d9c6a5c4ba3d3df1c
Autor:
Lara S. Boerenkamp, Cilia R. Pothast, Romy C. Dijkland, Kayleigh van Dijk, Gwendolyn N. Y. van Gorkom, Inge H. M. van Loo, Lotte Wieten, Constantijn J. M. Halkes, Mirjam H. M. Heemskerk, Catharina H. M. J. Van Elssen
Publikováno v:
American Journal of Hematology, 97(12), E457-E461. Wiley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c033ce6a4efb8c08d268b33b9c0c7511
https://doi.org/10.1002/ajh.26729
https://doi.org/10.1002/ajh.26729
Autor:
Salem H. Alshemmari, Judith C. W. Marsh, Rawad Rihani, Usama Gergis, Naeem Chaudhri, Antonio M. Risitano, Murtadha Al-Khabori, Ali Al-Ahmari, Qamar-Un-Nisa Chaudhry, Simone Cesaro, Constantijn J. M. Halkes, Mahmoud Aljurf, Tarek Ben Othman, Riad El Fakih, Mohamed Amine Bekadja, Ali Bazarbachi, Alaa Elhaddad, Jakob Passweg, Andrea Bacigalupo, Bassim Albeirouti, Britta Höchsmann, Hazzaa Alzahrani, Régis Peffault de Latour, Syed Osman Ahmed, Amir Ali Hamidieh, Eastern Mediterranean Blood, Walid Rasheed, Parvez Ahmad, Sultan Alotaibi, Marrow Transplantation, Austin G. Kulasekararaj, Per Ljungman, Josu de la Fuente, Raheel Iftikhar, Carlo Dufour
Publikováno v:
Bone Marrow Transplantation, 56(10), 2518-2532. SPRINGERNATURE
Aplastic anemia is a relatively rare but potentially fatal disorder, with a reported higher incidence in developing countries in comparison to the West. There are significant variations in epidemiological as well as etiological factors of bone marrow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989812f97fcb8bc00ff62ed6d639fafd
https://doi.org/10.1038/s41409-021-01332-8
https://doi.org/10.1038/s41409-021-01332-8
Autor:
Nawal AlShehry, Britta Höchsmann, Antonio M. Risitano, Syed Osman Ahmed, Hind Alotaibi, H Schrezenmeier, Régis Peffault de Latour, Simone Cesaro, Josu de la Fuente, Andrea Bacigalupo, Mansour Alfayez, Eliane Gluckman, Carlo Dufour, Shahid Iqbal, Mahmoud Aljurf, Jakob Passweg, Ibraheem H. Motabi, John F. DiPersio, Riad El Fakih, Constantijn J. M. Halkes
Publikováno v:
Transplantation and Cellular Therapy, 28(2). ELSEVIER SCIENCE INC
Idiopathic aplastic anemia is a rare and life-threatening disorder, and hematopoietic stem cell transplantation (HSCT) from a matched sibling donor (MSD) is the standard treatment strategy for young patients. Alternative donor transplantation (ADT) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de57ef39d0cb7788877e6e470e6b8e7c
https://hdl.handle.net/1887/3564258
https://hdl.handle.net/1887/3564258