Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Constandina Pospori"'
Autor:
C. Lo Celso, Reema Khorshed, Constandina Pospori, S. Gonzalez Anton, B. Partridge, Chiu Fan Lee, George Adams
Multi-potent progenitor (MPP) cells act as a key intermediary step between haematopoietic stem cells and the entirety of the mature blood cell system. Their eventual fate determination is thought to be achieved through migration in and out of spatial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93c09922a20706378b052fdeb4a5318
http://hdl.handle.net/10044/1/99575
http://hdl.handle.net/10044/1/99575
Autor:
Diana Passaro, Antoniana Batsivari, Constandina Pospori, Cristina Lo Celso, Myriam L. R. Haltalli, Dominique Bonnet
Publikováno v:
Nature Cell Biology. 22:7-17
Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal and haematopoietic cells regulate their function. The steady state HSC niche has been extensively studied. In this Review, we focus on how bone marrow microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::020171ba8566c8cf2b2e3b29edf7e2bc
https://doi.org/10.1038/s41556-019-0444-9
https://doi.org/10.1038/s41556-019-0444-9
Autor:
Chiara Pirillo, Flora Birch, Floriane S. Tissot, Sara Gonzalez Anton, Myriam Haltalli, Valentina Tini, Isabella Kong, Cécile Piot, Ben Partridge, Constandina Pospori, Karen Keeshan, Salvatore Santamaria, Edwin Hawkins, Brunangelo Falini, Andrea Marra, Delfim Duarte, Chiu Fan Lee, Edward Roberts, Cristina Lo Celso
Acute myeloid leukemia (AML) is a blood cancer of the myeloid lineage. Its prognosis remains poor, highlighting the need for new therapeutic and precision medicine approaches. AML symptoms often include cytopenias linked to loss of healthy hematopoie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd81d749d0e628654eff6a9ea3f1e36
Autor:
Hans J. Stauss, S. V. Gibson, Reema Khorshed, Constandina Pospori, D. Stampoulis, K. Sloan, Hector Huerga Encabo, John G. Gribben, Flora Birch, C. Christodoulidou, William Grey, Charis Georgiou, Sara Gonzalez-anton, F. Hearn-Yates, M.-N. Skoufou-Papoutsaki, Thomas N. Williams, Dominique Bonnet, Ronjon Chakraverty, Gretchen A Stevens, J. Hopkins, Myriam L. R. Haltalli, C. Lo Celso
Acute Myeloid Leukemia, a hematological malignancy with poor clinical outcome, is composed of hierarchically heterogeneous cells. We examine the contribution of this heterogeneity to disease progression in the context of anti-tumor immune responses a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456c4792dcba0a688a07ac286dabec4f
https://doi.org/10.1101/2020.12.21.414649
https://doi.org/10.1101/2020.12.21.414649
Autor:
Cristina Lo Celso, Reema Khorshed, Angelika Holler, Mathias Zech, Constandina Pospori, Hans J. Stauss, Sharyn Thomas, Zaida G. Ramirez-Ortiz, Maryam Ahmadi, Sara Ghorashian, Anjum Bashir Khan, Pedro Santos e Sousa, Pedro Veliça, Ronjon Chakraverty, Sara Gonzalez Anton, Calum Forrest, Emma C. Morris, Barry Flutter, Jim E. Griffin, Terry K. Means, Ben Carpenter, Clare L. Bennett
Publikováno v:
The Journal of Clinical Investigation
A key predictor for the success of gene-modified T cell therapies for cancer is the persistence of transferred cells in the patient. The propensity of less differentiated memory T cells to expand and survive efficiently has therefore made them attrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d3053192d8350deaa16b21176f0d69
http://europepmc.org/articles/PMC5919805
http://europepmc.org/articles/PMC5919805
Autor:
Erik Sahai, Krisztina Zuborne-Alapi, Jiten Manji, Amy A Kirkwood, Sarah Aref, Constandina Pospori, Adele K. Fielding, William Day, Ayse U. Akarca, SooWah Lee, Marc R. Mansour, I Puccio, Rachel J. Mitchell, Aditi Dey, Robert C. Muirhead, Katharine Bailey, Teresa Marafioti, Melanie Aguiar, Kristina Kirschner, Steven Hooper, Richard K. Burt, Kenton Cheuk Yan Ng, Cristina Lo Celso
We investigated and modeled the mesenchymal stromal cell (MSC) niche in adult acute lymphoblastic leukemia (ALL). We used gene expression profiling, cytokine/chemokine quantification, flow cytometry, and a variety of imaging techniques to show that M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d45c01fc617a63a81138a5ad83f72d
https://europepmc.org/articles/PMC6856969/
https://europepmc.org/articles/PMC6856969/
Autor:
Chrysi Christodoulidou, Maria-Nefeli Skoufou-Papoutsaki, Thomas N. Williams, Cristina Lo Celso, Shayin Gibson, Ronjon Chakraverty, Hans J. Stauss, Georgia Stevens, Francesca Hearn-Yeates, Sara Gonzalez-anton, Jack Hopkins, Reema Khorshed, Constandina Pospori, Dimitrios Stampoulis, Christiana Georgiou, Myriam L. R. Haltalli, Katherine Sloan, William Grey, Dominique Bonnet, Flora Birch
Publikováno v:
Experimental Hematology. 88:S75
Acute Myeloid Leukaemia (AML), is a haematological malignancy composed of hierarchically heterogeneous blasts. While leukaemic stem cells are known to initiate disease and drive relapse and progenitor-like populations form the bulk of the disease, le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0632cc540466905c66c2116658e1c78
https://doi.org/10.1016/j.exphem.2020.09.131
https://doi.org/10.1016/j.exphem.2020.09.131
Autor:
Antoniana Batsivari, Constandina Pospori, Dominique Bonnet, Diana Passaro, Cristina Lo Celso, Myriam L. R. Haltalli
Publikováno v:
Nature Cell Biology. 22:257-257
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578dae765299e98c06549a308aa7aa3f
https://doi.org/10.1038/s41556-020-0469-0
https://doi.org/10.1038/s41556-020-0469-0
Autor:
Antoniana, Batsivari, Myriam Luydmila Rachelle, Haltalli, Diana, Passaro, Constandina, Pospori, Cristina, Lo Celso, Dominique, Bonnet
Publikováno v:
Nature cell biology. 22(1)
Adult haematopoietic stem cells (HSCs) mainly reside in the bone marrow, where stromal and haematopoietic cells regulate their function. The steady state HSC niche has been extensively studied. In this Review, we focus on how bone marrow microenviron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ce77f5c438c4a261e126c381cab72e2
https://pubmed.ncbi.nlm.nih.gov/31969686
https://pubmed.ncbi.nlm.nih.gov/31969686
Autor:
Angelika Holler, Liquan Gao, Hans J. Stauss, Rafael Di Marco Barros, Graham P. Wright, Shao-An Xue, M Ahmadi, Emma C. Morris, Constandina Pospori, Sharyn Thomas, Sara Ghorashian, Max Topp
Publikováno v:
Oncoimmunology
In this study, we generated human MHC Class I-restricted CD4+ T cells specific for Epstein-Barr virus (EBV) and cytomegalovirus (CMV), two herpesviridae associated with lymphoma, nasopharyngeal carcinoma and medulloblastoma, respectively. Retroviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abfe0b1814fc8efd5269501256fb19a7
http://europepmc.org/articles/PMC3583927
http://europepmc.org/articles/PMC3583927