Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Constance Yeo"'
Autor:
Shuhui Lim, Regina Khoo, Yu-Chi Juang, Pooja Gopal, Huibin Zhang, Constance Yeo, Khong Ming Peh, Jinkai Teo, Simon Ng, Brian Henry, Anthony W. Partridge
Publikováno v:
ACS Central Science, Vol 7, Iss 2, Pp 274-291 (2020)
Externí odkaz:
https://doaj.org/article/5f5d414c219444a1a1f0c50dacdb5325
Autor:
Simon Ng, Alexander C. Brueckner, Soheila Bahmanjah, Qiaolin Deng, Jennifer M. Johnston, Lan Ge, Ruchia Duggal, Bahanu Habulihaz, Benjamin Barlock, Sookhee Ha, Ahmad Sadruddin, Constance Yeo, Corey Strickland, Andrea Peier, Brian Henry, Edward C. Sherer, Anthony W. Partridge
Publikováno v:
Journal of Medicinal Chemistry. 65:9789-9801
STIP1 homology and U-Box containing protein 1 (STUB1) plays a key role in maintaining cell health during stress and aging. Recent evidence suggested STUB1 also helps regulate immunity with the potential of clearing malignant cells. Indeed, we and oth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d4ec6db56ddbda74bf2aedff793236
https://doi.org/10.1021/acs.jmedchem.2c00406
https://doi.org/10.1021/acs.jmedchem.2c00406
Autor:
Anthony W. Partridge, Simon Ng, Brian Henry, Khong Ming Peh, Jinkai Teo, Yu-Chi Juang, Pooja Gopal, Constance Yeo, Shuhui Lim, Huibin Zhang, Regina Khoo
Publikováno v:
ACS Central Science
ACS Central Science, Vol 7, Iss 2, Pp 274-291 (2020)
ACS Central Science, Vol 7, Iss 2, Pp 274-291 (2020)
Mutations to RAS proteins (H-, N-, and K-RAS) are among the most common oncogenic drivers, and tumors harboring these lesions are some of the most difficult to treat. Although covalent small molecules against KRASG12C have shown promising efficacy ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44a90b33d5b7fecf479b41c081b0d8c
http://europepmc.org/articles/PMC7908030
http://europepmc.org/articles/PMC7908030
Autor:
Nikita Vostrosablin, Shuhui Lim, Pooja Gopal, Kveta Brazdilova, Sushmita Parajuli, Xiaona Wei, Anna Gromek, Martin Spale, Anja Muzdalo, Constance Yeo, Joanna Wardyn, Petr Mejzlik, Brian Henry, Anthony W. Partridge, Danny A. Bitton
Recent COVID-19 vaccines unleashed the potential of mRNA-based therapeutics. mRNA optimization is indispensable for reducing immunogenicity, ensuring stability, and maximizing protein output. We present mRNAid, an experimentally validated software fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::314b5fbc92c6f028857d124c9055e174
https://doi.org/10.1101/2022.04.04.486952
https://doi.org/10.1101/2022.04.04.486952
Autor:
Brian Henry, Shuhui Lim, Anthony W. Partridge, Pooja Gopal, Constance Yeo, Khong Ming Peh, Regina Khoo, Huibin Zhang, Jinkai Teo, Yu-Chi Juang, Simon Ng
Mutations to RAS proteins (H-, N-, and K-RAS) are amongst the most common oncogenic drivers and tumors harboring these lesions are some of the most difficult to treat. Although the recently discovered covalent small molecules against the KRASG12C mut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13fee929c6c9764db04c251fd5a8c855
https://doi.org/10.1101/2020.06.26.174565
https://doi.org/10.1101/2020.06.26.174565