Výsledky vyhledávání - "Constance Rueff-Weisenthal"

Bevacizumab-induced tumor calcifications can be elicited in glioblastoma microspheroid culture and represent massive calcium accumulation death (MCAD) of tumor endothelial cells

Autor: Constance Rueff-Weisenthal, Cindy Brunschwiler, Larry Weiseenthal, Summer Williamson

Publikováno v: Nature Precedings.

Bähr and colleagues reported that 22 of 36 glioblastoma patients treated with bevacizumab showed tumor calcifications on 8 week post therapy follow up with MRI. Early tumor calcification strongly predicted for response, time to progression, and over

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d6f8c6073ab0cadfa2b32dfe7f2bcc
https://doi.org/10.1038/npre.2012.7069.1

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Death of human tumor endothelial cells in vitro through a probable calcium-associated mechanism induced by bevacizumab and detected via a novel method

Autor: Larry Weisenthal, Constance Rueff-Weisenthal, Haddy Liu

Publikováno v: Nature Precedings

We isolated three dimensional cell clusters from fresh human solid tumors and also isolated human neoplastic and normal lymphatic cells. Cells were cultured for 96 hours with and without bevacizumab and other agents. At concentrations of bevacizumab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb154cedd1c6cf2b7e9ffdc5c726168
https://doi.org/10.1038/npre.2010.4499.1

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Serum inhibition of massively calcified endosomal death (MCED) in endothelial cells is a putative mechanism of resistance to bevacizumab (BEV) and other anti-angiogenic (anti-angio) agents

Autor: Summer Williamson, Cindy Brunshwiler, Larry M. Weisenthal, Esther Moon, Constance Rueff-Weisenthal

Publikováno v: Journal of Clinical Oncology. 33:e22005-e22005

e22005 Background: Bahr et al reported that 22 of 36 glioblastoma (GBM) patients treated with BEV showed tumor (TUM) calciﬁcations (CALC) on 8 wk follow up post therapy. Early TUM CALC strongly pre...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8de4320358aca97daf3eaa8a6936d3cc
https://doi.org/10.1200/jco.2015.33.15_suppl.e22005

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