Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Constance M. Cullen"'
Autor:
Sherry Thornton, Gregory P. Boivin, Monica L. DeLay, Raphael Hirsch, Edward F. Rosloniec, Constance M. Cullen, Linda K. Myers, Li Zuo
Publikováno v:
The Journal of Immunology. 168:2554-2559
T cells play a central role in many autoimmune diseases. A method to specifically target the function of autoreactive T cell clones would avoid the global immunosuppression associated with current therapies. To develop a molecule capable of inhibitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb66f325f8cd2dd8138149dc4784bbfa
https://doi.org/10.4049/jimmunol.168.5.2554
https://doi.org/10.4049/jimmunol.168.5.2554
Autor:
Constance M. Cullen, Monica DeLay, Eric T. Becken, Raphael Hirsch, Stephen C. Jameson, Charles Cottrell, E Choi
Publikováno v:
Cellular Immunology. 192:54-62
Activation of antigen-specific T cell clones in vivo might be possible by generating soluble MHC molecules; however, such molecules do not induce effective T cell responses unless cross-linked. As a first step in generating a soluble MHC molecule tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a0295761951f9cc6d4b5e49cb536a9
https://doi.org/10.1006/cimm.1998.1434
https://doi.org/10.1006/cimm.1998.1434
Publikováno v:
Infection and Immunity. 63:2141-2146
Toxic shock syndrome toxin 1 (TSST-1), a superantigen produced by Staphylococcus aureus, is a causative agent of toxic shock syndrome (TSS). This superantigen is a potent stimulator of T cells and macrophages/monocytes, resulting in the release of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66574ae84c4783a5c0f1e9cc3228e446
https://doi.org/10.1128/iai.63.6.2141-2146.1995
https://doi.org/10.1128/iai.63.6.2141-2146.1995
Publikováno v:
Infection and Immunity. 63:509-515
Structure-function studies have revealed that the region between amino acids 115 and 141 of toxic shock syndrome toxin 1 (TSST-1) constitutes a biologically active domain. A critical residue appears to be histidine 135, since a site-directed mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9aa651656cf94ff6e8e15b92450fff
https://doi.org/10.1128/iai.63.2.509-515.1995
https://doi.org/10.1128/iai.63.2.509-515.1995
Autor:
Horst Bluethmann, Holly Heeg, Peter F. Bonventre, John D. Mountz, Carl K. Edwards, Constance M. Cullen
Publikováno v:
Pathobiology. 63:293-304
Recombinant toxic shock syndrome toxin-1 (rTSST-1) administered to MRL-lpr/lpr TCR V beta 8.2 transgenic mice at doses of 0.1 microgram/mouse resulted in 100% mortality. This was an unexpected finding since TSST-1 does not activate V beta 8.2 T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc75b15354fae6522dc8c116478099e0
https://doi.org/10.1159/000163965
https://doi.org/10.1159/000163965
Autor:
C Kouvidou, D. Rontogianni, Panagiotis Kanavaros, Constance M. Cullen, M.J.J. Gijbels, Kazunori Nakagawa, David G. Kaufman, Ko Okumura, Susumu Ohkawara, Georg Kraal, K. Darivianaki, Kojiro Ichikawa, H.I. Gallardo Torres, Horst Bluethmann, I. Panayiotides, Yusri Ali Elsayed, G Delides, Naruo Kuwashima, Carl K. Edwards, Katsuo Sueishi, Holly Heeg, Peter F. Bonventre, Tzardi M, Takushi Tadakuma, John D. Mountz, Haruko Koizumi, Hisako Tanaka, Saburo Saito, Eitan Friedman, E. Karidi, Harm HogenEsch, Tatsuji Nomura, Akira Sonoda, Craig D. Albright, Datseris G, Hideo Yagita
Publikováno v:
Pathobiology. 63:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04ca492a7961936b03cf09ec61a58229
https://doi.org/10.1159/000163964
https://doi.org/10.1159/000163964
Autor:
K. Darivianaki, H.I. Gallardo Torres, Harm HogenEsch, Eitan Friedman, Akira Sonoda, Datseris G, John D. Mountz, Tzardi M, Carl K. Edwards, Hideo Yagita, Holly Heeg, Hisako Tanaka, Saburo Saito, I. Panayiotides, D. Rontogianni, Susumu Ohkawara, G Delides, Naruo Kuwashima, Tatsuji Nomura, Craig D. Albright, Takushi Tadakuma, C Kouvidou, M.J.J. Gijbels, Peter F. Bonventre, Yusri Ali Elsayed, Kojiro Ichikawa, Katsuo Sueishi, Georg Kraal, Constance M. Cullen, Kazunori Nakagawa, David G. Kaufman, E. Karidi, Haruko Koizumi, Panagiotis Kanavaros, Ko Okumura, Horst Bluethmann
Publikováno v:
Pathobiology. 63:352-352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c7583904e199aeba312d1e9623d7b1d
https://doi.org/10.1159/000163973
https://doi.org/10.1159/000163973