Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Constance J. Mietus"'
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Akademický článek
Neuronal somatic plasmalemmal permeability and dendritic beading caused by head rotational traumatic brain injury in pigs–An exploratory study
Autor: James P. Harris, Constance J. Mietus, Kevin D. Browne, Kathryn L. Wofford, Carolyn E. Keating, Daniel P. Brown, Brian N. Johnson, John A. Wolf, Douglas H. Smith, Akiva S. Cohen, John E. Duda, D. Kacy Cullen
Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)
Closed-head traumatic brain injury (TBI) is induced by rapid motion of the head, resulting in diffuse strain fields throughout the brain. The injury mechanism(s), loading thresholds, and neuroanatomical distribution of affected cells remain poorly un
Externí odkaz: https://doaj.org/article/6199c5a343c2489d9d4370f3f3f80d33
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3
Akademický článek
Premature aortic smooth muscle cell differentiation contributes to matrix dysregulation in Marfan Syndrome.
Autor: Matthew Dale, Matthew P Fitzgerald, Zhibo Liu, Trevor Meisinger, Andrew Karpisek, Laura N Purcell, Jeffrey S Carson, Paul Harding, Haili Lang, Panagiotis Koutakis, Melissa Suh, Rishi Batra, Constance J Mietus, George Casale, Iraklis Pipinos, B Timothy Baxter, Wanfen Xiong
Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0186603 (2017)
Thoracic aortic aneurysm and dissection are life-threatening complications of Marfan syndrome (MFS). Studies of human and mouse aortic samples from late stage MFS demonstrate increased TGF-β activation/signaling and diffuse matrix changes. However,
Externí odkaz: https://doaj.org/article/92ba3ebef25842e8954c77e6609ef478
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5
Abnormal Microvascular Architecture, Fibrosis, and Pericyte Characteristics in the Calf Muscle of Peripheral Artery Disease Patients with Claudication and Critical Limb Ischemia
Autor: Gleb Haynatzki, George P. Casale, Matthew Fuglestad, Julian K S Kim, Holly DeSpiegelaere, Gregory Willcockson, Constance J. Mietus, Petros Karvelis, Panagiotis Koutakis, Christina Shields, Hernan Hernandez, Nicholas Lambert, Timothy J Lackner, Iraklis I. Pipinos
Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 2575, p 2575 (2020)
Journal of Clinical Medicine
Volume 9
Issue 8
Work from our laboratory documents pathological events, including myofiber oxidative damage and degeneration, myofibrosis, micro-vessel (diameter = 50&ndash
150 &mu
m) remodeling, and collagenous investment of terminal micro-vessels (diamet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f51d52cb6f68b094e89efa7652c8722
https://www.mdpi.com/2077-0383/9/8/2575
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6
Altered Metabolomic Profile in Patients with Peripheral Artery Disease
Autor: Panagiotis Koutakis, Gleb Haynatzki, Marco E. Franco, Ramon Lavado, Ian Sawicki, Iraklis I. Pipinos, Ahmed Ismaeel, Matthew Fuglestad, Evlampia Papoutsi, Robert S. Smith, William T. Bohannon, Constance J. Mietus, George P Casale
Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine; Volume 8; Issue 9; Pages: 1463
Journal of Clinical Medicine, Vol 8, Iss 9, p 1463 (2019)
Peripheral artery disease (PAD) is a common atherosclerotic disease characterized by narrowed or blocked arteries in the lower extremities. Circulating serum biomarkers can provide significant insight regarding the disease progression. Here, we explo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbc14b8cc1c9bb6a535dbc9afc6d207
http://europepmc.org/articles/PMC6780416
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7
Collateral Development and Arteriogenesis in Hindlimbs of Swine After Ligation of Arterial Inflow
Autor: George P. Casale, Mark A. Carlson, Joshua S. Ungar, Constance J. Mietus, Shuai Li, Iraklis I. Pipinos, Yue Gao, Neesha S. Patel, Matthew Fuglestad, Shruthi Aravind
Publikováno v: J Surg Res
Background Development of collateral vasculature is key in compensating for arterial occlusions in patients with peripheral artery disease (PAD). We aimed to examine the development of collateral pathways after ligation of native vessels in a porcine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1587307d86e2ccaa3e41911b872cfa73
https://pubmed.ncbi.nlm.nih.gov/31986359
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8
Abstract 340: Microvascular Pathology in Peripheral Artery Disease
Autor: George P. Casale, Iraklis I. Pipinos, Timothy J Lackner, Constance J. Mietus, Peter Karvelis, Hernan Hernandez, Nicholas Lambert
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Background: Peripheral Artery Disease (PAD) is caused by atherosclerotic narrowing of arteries supplying the legs. PAD-induced myopathy is characterized by myofiber degeneration and progressive fibrosis. Qualitative histological review suggests patho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7f53059f4b0f2986733171e21eedb82f
https://doi.org/10.1161/atvb.38.suppl_1.340
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10
Rebuilding Brain Circuitry with Living Micro-Tissue Engineered Neural Networks
Autor: D. Kacy Cullen, Constance J. Mietus, Laura A. Struzyna, H. Isaac Chen, Dayo O. Adewole, Douglas H. Smith, John A. Wolf
Publikováno v: Tissue Engineering Part A. 21:2744-2756
Prominent neuropathology following trauma, stroke, and various neurodegenerative diseases includes neuronal degeneration as well as loss of long-distance axonal connections. While cell replacement and axonal pathfinding strategies are often explored
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604948f81adfe2860eca6eae41142bec
https://doi.org/10.1089/ten.tea.2014.0557
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