Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Constance E Brinckerhoff"'
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121140 (2015)
Patients with early stage, radial growth phase (RGP) melanoma have a 97% survival rate; however, when the melanoma progresses to the invasive vertical growth phase (VGP), survival rates decrease to 15%. The targets of many clinical trials are the kno
Externí odkaz:
https://doaj.org/article/3ea55b32632348fbae5e023ac0280b54
Autor:
Mary Jo Turk, Marcus W. Bosenberg, Marc S. Ernstoff, Constance E. Brinckerhoff, David W. Mullins, Katelyn T. Byrne, Tamer B. Shabaneh, Andrea Boni, Brian T. Malik, Peisheng Zhang, Shannon M. Steinberg
Supplementary Figure 1: Vemurafenib arrests growth of Braf/Pten melanomas. Supplementary Figure 2: PLX4720 does not alter the character of CD4 helper T cells in the tumor microenvironment. Supplementary Figure 3: PLX4720 does not induce apoptosis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1491c221d8ca6b52185f1d074cced8fa
https://doi.org/10.1158/2326-6066.22536922
https://doi.org/10.1158/2326-6066.22536922
Autor:
Mary Jo Turk, Marcus W. Bosenberg, Marc S. Ernstoff, Constance E. Brinckerhoff, David W. Mullins, Katelyn T. Byrne, Tamer B. Shabaneh, Andrea Boni, Brian T. Malik, Peisheng Zhang, Shannon M. Steinberg
Supplementary Figure Legends from BRAF Inhibition Alleviates Immune Suppression in Murine Autochthonous Melanoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d2c97a93d35778048ba1697904e7b
https://doi.org/10.1158/2326-6066.22536925
https://doi.org/10.1158/2326-6066.22536925
Autor:
Mary Jo Turk, Marcus W. Bosenberg, Marc S. Ernstoff, Constance E. Brinckerhoff, David W. Mullins, Katelyn T. Byrne, Tamer B. Shabaneh, Andrea Boni, Brian T. Malik, Peisheng Zhang, Shannon M. Steinberg
A growing body of evidence suggests that BRAF inhibitors, in addition to their acute tumor growth–inhibitory effects, can also promote immune responses to melanoma. The present study aimed to define the immunologic basis of BRAF-inhibitor therapy u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a81d74c575ec1d62de9daa3822f07ef8
https://doi.org/10.1158/2326-6066.c.6548275.v1
https://doi.org/10.1158/2326-6066.c.6548275.v1
Melanoma incidence is increasing worldwide, and metastatic melanoma is almost completely resistant to every known therapy. New approaches to treating melanoma are urgently needed, and a greater understanding of the biology of melanoma invasion and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b084168d973aff230ba701a882e0136
https://doi.org/10.1158/0008-5472.c.6496277
https://doi.org/10.1158/0008-5472.c.6496277
Supplementary Table 1 from RNA Interference Inhibition of Matrix Metalloproteinase-1 Prevents Melanoma Metastasis by Reducing Tumor Collagenase Activity and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b261b6e99053a998dc579db7ce1a4af9
https://doi.org/10.1158/0008-5472.22370126.v1
https://doi.org/10.1158/0008-5472.22370126.v1
Supplementary Figure 1 from RNA Interference Inhibition of Matrix Metalloproteinase-1 Prevents Melanoma Metastasis by Reducing Tumor Collagenase Activity and Angiogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062c08b12761a40d2ec0ace032dc1470
https://doi.org/10.1158/0008-5472.22370129
https://doi.org/10.1158/0008-5472.22370129
Autor:
Dieter Manstein, Martin W. LaFleur, Arlene H. Sharpe, Marcelo Pereira da Silva, Lajos Kemény, Mack Y. Su, Kristen E. Pauken, Masayoshi Kawakubo, David E. Fisher, S. Alireza Rabi, Tal Hadad Erlich, Catherine J. Wu, Rumya Raghavan, Genevieve M. Boland, Edward P. Browne, Mamunur Rashid, Yu Xu, Mai P. Hoang, Dennie T. Frederick, Jennifer A. Lo, Constance E. Brinckerhoff, Jennifer Allouche, David W. Mullins, David J. Adams, Anita A. J. van der Sande, Vikram R. Juneja, Mohsen Malehmir, Levi A. Garraway, David J. Lieb, Gordon J. Freeman, Keith T. Flaherty, Gyulnara G. Kasumova, Belinda Wang, Elisabeth Roider, Nir Hacohen, Whitney Silkworth, Qing Yu Weng
Publikováno v:
Sci Transl Med
Although immune checkpoint inhibitors (ICIs), such as anti-programmed cell death protein 1 (PD-1), can deliver durable anti-tumor effects, most patients with cancer fail to respond. Recent studies suggest that ICI efficacy correlates with a higher lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c593d3a3370645e186a5a9a975b8e9
https://doi.org/10.1126/scitranslmed.abd8636
https://doi.org/10.1126/scitranslmed.abd8636
Autor:
Constance E. Brinckerhoff
Publikováno v:
Matrix Metalloproteinases in Health and Disease. :i-xiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af885028f86ddd177568362e57cbb2bf
https://doi.org/10.1142/9789813207554_fmatter
https://doi.org/10.1142/9789813207554_fmatter
Autor:
Constance E. Brinckerhoff
Publikováno v:
Matrix Metalloproteinases in Health and Disease. :267-280
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9458ac8d145598bd653ff8c4d9a543
https://doi.org/10.1142/9789813207554_bmatter
https://doi.org/10.1142/9789813207554_bmatter