Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Constance Delaby"'
Autor:
Sylvain Lehmann, Susanna Schraen-Maschke, Luc Buée, Jean-Sébastien Vidal, Constance Delaby, Christophe Hirtz, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Olivier Hanon, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-14 (2024)
Abstract Background Current AT(N) stratification for Alzheimer’s disease (AD) accounts for complex combinations of amyloid (A), tau proteinopathy (T) and neurodegeneration (N) signatures. Understanding the transition between these different stages
Externí odkaz:
https://doaj.org/article/c860af25033746cb82e1ae7cdbcb2d80
Autor:
Pablo Mohaupt, Marie-Laure Pons, Jérôme Vialaret, Constance Delaby, Christophe Hirtz, Sylvain Lehmann
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-4 (2022)
Abstract Synaptic degeneration is an early event closely associated with the course of Alzheimer’s disease (AD). The identification of synaptic blood biomarkers is, therefore, of great interest and clinical relevance. The levels of most synaptic pr
Externí odkaz:
https://doaj.org/article/fa4002ff7cac4b50b7dfddaf9d9b06b7
Autor:
Constance Delaby, Teresa Estellés, Nuole Zhu, Javier Arranz, Isabel Barroeta, María Carmona-Iragui, Ignacio Illán-Gala, Miguel Ángel Santos-Santos, Miren Altuna, Isabel Sala, M. Belén Sánchez-Saudinós, Laura Videla, Sílvia Valldeneu, Andrea Subirana, Mireia Tondo, Francisco Blanco-Vaca, Sylvain Lehmann, Olivia Belbin, Rafael Blesa, Juan Fortea, Alberto Lleó, Daniel Alcolea
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background Cerebrospinal fluid (CSF) Aβ1–42 levels and the Aβ1–42/Aβ1–40 ratio are markers of amyloid pathology, but previous studies suggest that their levels might be influenced by additional pathophysiological processes. Aims To
Externí odkaz:
https://doaj.org/article/a354d1eb010a43359f60c319d468d2bd
Autor:
Pablo Mohaupt, Xavier Roucou, Constance Delaby, Jérôme Vialaret, Sylvain Lehmann, Christophe Hirtz
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Translation involves the biosynthesis of a protein sequence following the decoding of the genetic information embedded in a messenger RNA (mRNA). Typically, the eukaryotic mRNA was considered to be inherently monocistronic, but this paradigm is not i
Externí odkaz:
https://doaj.org/article/9cc3e8bbf7294c709577a5da0febfed6
Autor:
Constance Delaby, Olivier Bousiges, Damien Bouvier, Catherine Fillée, Anthony Fourier, Etienne Mondésert, Nicolas Nezry, Souheil Omar, Isabelle Quadrio, Benoit Rucheton, Susanna Schraen-Maschke, Vincent van Pesch, Stéphanie Vicca, Sylvain Lehmann, Aurelie Bedel
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. This field of neurology has evolved considerably in recent years with the improvement of analytical methods, allow
Externí odkaz:
https://doaj.org/article/b931b35796fd4807bbef259aa2ce127f
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Peripheral inflammation mechanisms involved in Alzheimer's disease (AD) have yet to be accurately characterized and the identification of blood biomarker profiles could help predict cognitive decline and optimize patient care. Blood biomarke
Externí odkaz:
https://doaj.org/article/076f0bfa945b49fcac2db44a677b9cc7
Autor:
Sylvain Lehmann, Julien Dumurgier, Xavier Ayrignac, Cecilia Marelli, Daniel Alcolea, Juan Fortea Ormaechea, Eric Thouvenot, Constance Delaby, Christophe Hirtz, Jérôme Vialaret, Nelly Ginestet, Elodie Bouaziz-Amar, Jean-Louis Laplanche, Pierre Labauge, Claire Paquet, Alberto Lleo, Audrey Gabelle, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2020)
Abstract Background Amyloid pathology, which is one of the characteristics of Alzheimer’s disease (AD), results from altered metabolism of the beta-amyloid (Aβ) peptide in terms of synthesis, clearance, or aggregation. A decrease in cerebrospinal
Externí odkaz:
https://doaj.org/article/aca109942c8141949ef7cdc389b65448
Autor:
Sylvain Lehmann, Constance Delaby, Guilaine Boursier, Cindy Catteau, Nelly Ginestet, Laurent Tiers, Aleksandra Maceski, Sophie Navucet, Claire Paquet, Julien Dumurgier, Eugeen Vanmechelen, Hugo Vanderstichele, Audrey Gabelle
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Background: Cerebrospinal fluid (CSF) biomarkers (Aβ peptides and tau proteins) improved the diagnosis of Alzheimer’s disease (AD) in research and clinical settings. We previously described the PLM-scale (Paris-Lille-Montpellier study), which comb
Externí odkaz:
https://doaj.org/article/ad80b40a8fb742abb4f089e76dce60d7
Autor:
Sarah Millot, Constance Delaby, Boualem Moulouel, Thibaud Lefebvre, Nathalie Pilard, Nicolas Ducrot, Cécile Ged, Philippe Lettéron, Lucia de Franceschi, Jean Charles Deybach, Carole Beaumont, Laurent Gouya, Hubert De Verneuil, Saïd Lyoumi, Hervé Puy, Zoubida Karim
Publikováno v:
Haematologica, Vol 102, Iss 2 (2017)
Hemolysis occurring in hematologic diseases is often associated with an iron loading anemia. This iron overload is the result of a massive outflow of hemoglobin into the bloodstream, but the mechanism of hemoglobin handling has not been fully elucida
Externí odkaz:
https://doaj.org/article/aac1a1886b7c4ca28849a86641e56d33
Clinical measurement of Hepcidin-25 in human serum: Is quantitative mass spectrometry up to the job?
Autor:
Constance Delaby, Jérôme Vialaret, Pauline Bros, Audrey Gabelle, Thibaud Lefebvre, Hervé Puy, Christophe Hirtz, Sylvain Lehmann
Publikováno v:
EuPA Open Proteomics, Vol 3, Iss C, Pp 60-67 (2014)
From its discovery, hepcidin has generated many hopes in terms of diagnosis and management of a wide variety of iron-related diseases. However, in clinical use its accurate quantification remains a challenge due to the limited sensitivity, specificit
Externí odkaz:
https://doaj.org/article/f02e2c48a2384a778557fb5812e52ce8