Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Constanţa Ganea"'
Autor:
Maria Teodora Ilie, Vlad Cosoreanu, Ramona Madalina Babes, Roxana Gabriela Sandu, Maria Catalina Ceausescu, Ioana Teodora Tofolean, Oana Elena Baran, Irina Baran, Ruxandra Irimia, Constanţa Ganea
Publikováno v:
Documenta Haematologica. 34:52-61
Doxorubicin is a widely used chemotherapeutic drug, effective on patients with acute lymphoblastic leukemia but associated with significant long term cardio-toxicity. Menadione (vitamine K3) and the flavonoid quercetin are known as strong apoptogens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a44c80f9a7b10f78bc277a675ac708f
https://doi.org/10.1515/dch-2015-0005
https://doi.org/10.1515/dch-2015-0005
Autor:
Carmen Mariana Aanei, Alexandru Filippi, Maria-Magdalena Mocanu, Tiphanie Picot, János Szöllősi, Constanţa Ganea, Lydia Campos, Péter Nagy
Publikováno v:
International journal of food sciences and nutrition. 69(5)
In this study, we evaluated the effects of epigallocatechin-3-O-gallate (EGCG) in two cancer cell lines, A-431 overexpressing ErbB1 and SK-BR-3, overexpressing ErbB2. EGCG treatment showed dose-dependent collapse of mitochondrial membrane potential (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e32c644c3abacf6e4591a428e77d0c
https://pubmed.ncbi.nlm.nih.gov/29157036
https://pubmed.ncbi.nlm.nih.gov/29157036
Publikováno v:
Food and Chemical Toxicology. 61:94-100
Cell membrane fluidity, which can be altered by oxidative stress, plays an important role in the cell physiology. Flavonoids are among the most studied food substances that prevent and/or reduce oxidative stress, but their action mechanisms are far f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd12de4299f4750044602b4a9e8df63
https://doi.org/10.1016/j.fct.2013.03.007
https://doi.org/10.1016/j.fct.2013.03.007
Autor:
Constanţa Ganea, Diana Ionescu
Publikováno v:
European Biophysics Journal. 41:307-318
Quercetin (QCT) is an important bioactive natural compound found in numerous edible plants. Since the lipid bilayer represents an essential compound of the cell membrane, QCT's direct interaction with this structure is of great interest. Therefore, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6867bd6e91171cc34faf4ca036601db
https://doi.org/10.1007/s00249-011-0786-0
https://doi.org/10.1007/s00249-011-0786-0
Autor:
Irina Baran, Maria-Magdalena Mocanu, Dilip Shrestha, Constanţa Ganea, Péter Nagy, Tímea Váradi, Laura Georgescu, Éva Katona, János Szöllősi
Publikováno v:
Journal of natural products. 77(2)
Since the administration of synthetic medicines is associated with drug resistance and undesired side effects, utilization of natural compounds could be an alternative and complementary modality to inhibit or prevent the development of tumors. Epigal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36bc4dc20647fa5b8ade0ca2a892bbf2
https://pubmed.ncbi.nlm.nih.gov/24456004
https://pubmed.ncbi.nlm.nih.gov/24456004
Autor:
Ionela Victoria Neagoe, Magdalena Mocanu, Gina Manda, Denisa Margina, Diana Ionescu, Constanţa Ganea, Daniela Gradinaru, Mihaela Ilie
Publikováno v:
General physiology and biophysics. 31(1)
Quercetin and epigallocatechin gallate are two of the most abundant polyphenols in dietary plants, including apples, onions, red wine and green tea. The bioactivity of polyphenols is linked to their ability to interact with cell membranes without bei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c408715bbb381c00f3cfefc52de23106
https://pubmed.ncbi.nlm.nih.gov/22781828
https://pubmed.ncbi.nlm.nih.gov/22781828
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Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0182293 (2017)
Na+/H+ exchange is essential for survival of all organisms, having a role in the regulation of the intracellular Na+ concentration, pH and cell volume. Furthermore, Na+/H+ exchangers were shown to be involved in the virulence of the bacterium Yersini
Externí odkaz:
https://doaj.org/article/318cdeed6d3944b387c7439ad247bdf2
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101575 (2014)
Na+/H+ antiporters are integral membrane proteins that are present in almost every cell and in every kingdom of life. They are essential for the regulation of intracellular pH-value, Na+-concentration and cell volume. These secondary active transport
Externí odkaz:
https://doaj.org/article/c70f036df6274bf8b421154546e4d6ad