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pro vyhledávání: '"Consensus site"'
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Autor:
Lars Damen, Toin H. van Kuppevelt, Willeke F. Daamen, Thierry van Wessel, Els M.A. van de Westerlo, Elly M. M. Versteeg
Publikováno v:
Glycoconjugate Journal
Glycoconjugate Journal, 37, 4, pp. 445-455
Glycoconjugate Journal, 37, 445-455
Glycoconjugate Journal, 37, 4, pp. 445-455
Glycoconjugate Journal, 37, 445-455
Heparan sulfate (HS) is a linear polysaccharide with high structural diversity. Different HS epitopes have been detected and localized using single chain variable fragment (scFv) antibodies from a ‘single pot’ phage display library containing a r
Autor:
Keelan Z. Guiley, Haritha Narasimhan, Anushweta Asthana, Hinrich Boeger, Robert Shelansky, Sarvind Tripathi, Alexander Hirschi, Tilini U. Wijeratne, Michael J. Doody, Parameshwaran Ramanan, Gerd A Mueller, Seth M. Rubin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Nature Communications
Nature communications, vol 13, iss 1
Nature Communications
Nature communications, vol 13, iss 1
The chromatin architecture in promoters is thought to regulate gene expression, but it remains uncertain how most transcription factors (TFs) impact nucleosome position. The MuvB TF complex regulates cell-cycle dependent gene-expression and is critic
Autor:
Anjani Kumar Singh, Sanjay Kumar, Vishnu Swarup, Deepika Gupta, Lung-Wen Tsai, Rajni Dubey, Pavan Kumar, Himanshu Narayan Singh
Publikováno v:
Life, Vol 11, Iss 1185, p 1185 (2021)
Life
Volume 11
Issue 11
Life
Volume 11
Issue 11
Methylation of adenosines at N6 position (m6A) is the most frequent internal modification in mRNAs of the human genome and attributable to diverse roles in physiological development, and pathophysiological processes. However, studies on the role of m
Autor:
Supriyo Bhatticharya, Weidong Hu, Patty Wong, Alonso Tapia, John E. Shively, Teresa Hong, Karine Bagramyan, Markus Kalkum
Publikováno v:
The Journal of Biological Chemistry
CEACAM1-LF, a homotypic cell adhesion adhesion molecule, transduces intracellular signals via a 72 amino acid cytoplasmic domain that contains two immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and a binding site for β-catenin. Phosphorylat
Publikováno v:
Nucleic Acids Research
The gene cro promotes lytic growth of phages through binding of Cro protein dimers to regulatory DNA sites. Most Cro proteins are one-to-one orthologs, yet their sequence, structure and binding site sequences are quite divergent across lambdoid phage
Autor:
Carole Peluso-Iltis, Pierre Poussin-Courmontagne, Judit Osz, Yassmine Chebaro, Bruno Kieffer, Natacha Rochel, Justine Wolf, Alastair G. McEwen
Publikováno v:
Molecular and Cellular Endocrinology
Molecular and Cellular Endocrinology, Elsevier, 2019, 481, pp.44-52. ⟨10.1016/j.mce.2018.11.008⟩
Molecular and Cellular Endocrinology, Elsevier, 2019, 481, pp.44-52. ⟨10.1016/j.mce.2018.11.008⟩
Retinoid X Receptors (RXRs) act as dimer partners for several nuclear receptors including itself, binding to genomic DNA response elements and regulating gene transcription with cell and gene specificity. As homodimers, RXRs bind direct repeats of th
Autor:
Robin Andersson, Peter Brodersen, Carlotta Porcelli, Martin Lewinski, Tino Köster, Laura Arribas-Hernández, Dorothee Staiger, Sarah Rennie
Publikováno v:
Arribas-Hernández, L, Rennie, S, Köster, T, Porcelli, C, Lewinski, M, Staiger, D, Andersson, R & Brodersen, P 2021, ' Principles of mRNA targeting via the Arabidopsis m 6 A-binding protein ECT2 ', eLife, vol. 10, e72375 . https://doi.org/10.7554/eLife.72375
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
eLife
Specific recognition of N6-methyladenosine (m6A) in mRNA by RNA-binding proteins containing a YT521-B homology (YTH) domain is important in eukaryotic gene regulation. The Arabidopsis YTH domain protein ECT2 is thought to bind to mRNA at URU(m6A)Y si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ce899c90a4e3080cf4bf7065430ba3
https://doi.org/10.1101/2021.04.18.440342
https://doi.org/10.1101/2021.04.18.440342
Autor:
Kazuchika Nishitsuji, Yukishige Ito, Midori Ikezaki, Ko Matsumura, Yukinao Shibukawa, Shino Manabe, Yoshito Ihara, Yoshinao Wada
Publikováno v:
Biochimie. 192
The Trp-x-x-Trp (W-x-x-W) peptide motif, a consensus site for C-mannosylation, is the functional motif in cytokine type I receptors or thrombospondin type I repeat (TSR) superfamily proteins. W-x-x-W motifs are important for physiological and patholo
Autor:
Roberta Piva, Federica Brugnoli, Elisabetta Lambertini, Simone Patergnani, Silvia Grassilli, Ervin Nika, Paolo Pinton, Federica Vezzali, Silvano Capitani, Valeria Bertagnolo
Publikováno v:
Journal of Cellular and Molecular Medicine
It has been recently demonstrated that high pre‐treatment levels of miR‐29b positively correlated with the response of patients with acute myeloid leukaemia (AML) to hypomethylating agents. Upmodulation of miR‐29b by restoring its transcription