A Phase Ib Study of Preoperative, Locoregional IRX-2 Cytokine Immunotherapy to Prime Immune Responses in Patients with Early-Stage Breast Cancer.

Autor: Page DB; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon. david.page2@providence.org., Pucilowska J; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Sanchez KG; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Conrad VK; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Conlin AK; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Acheson AK; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Perlewitz KS; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Imatani JH; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Aliabadi-Wahle S; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Moxon N; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Mellinger SL; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Seino AY; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Martel M; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Wu Y; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Sun Z; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Redmond WL; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Rajamanickam V; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Waddell D; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Laxague D; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon., Shah M; Brooklyn Therapeutics, Brooklyn, New York., Chang SC; Medical Data Research Center, Providence St. Joseph Health, Portland, Oregon., Urba WJ; Earle A. Chiles Research Institute, Providence Cancer Institute, Portland, Oregon.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2020 Apr 01; Vol. 26 (7), pp. 1595-1605. Date of Electronic Publication: 2019 Dec 12.

CpG preconditioning regulates miRNA expression that modulates genomic reprogramming associated with neuroprotection against ischemic injury.

Autor: Vartanian KB; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, USA., Mitchell HD; Pacific Northwest National Laboratory, Richland, Washington, USA., Stevens SL; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, USA., Conrad VK; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, USA., McDermott JE; Pacific Northwest National Laboratory, Richland, Washington, USA., Stenzel-Poore MP; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, USA.

Publikováno v: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2015 Feb; Vol. 35 (2), pp. 257-66. Date of Electronic Publication: 2014 Nov 12.

Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism.

Autor: Leung PY; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR 97239, USA., Stevens SL, Packard AE, Lessov NS, Yang T, Conrad VK, van den Dungen NN, Simon RP, Stenzel-Poore MP

Publikováno v: Stroke [Stroke] 2012 May; Vol. 43 (5), pp. 1383-9. Date of Electronic Publication: 2012 Mar 08.