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of 10
pro vyhledávání: '"Conrad Tou"'
Publikováno v:
International Journal of Diabetes in Developing Countries. 34:201-209
The prevalence of type 2 diabetes mellitus (T2DM) is rapidly increasing in India. Additional antihyperglycemic treatment options are important for patients who cannot achieve glycemic control through diet and exercise. The dipeptidyl peptidase 4 (DPP
Publikováno v:
Diabetes/Metabolism Research and Reviews. 28:268-275
Background Few studies have assessed the use of new oral anti-diabetic agents in Asian populations. This study assesses the efficacy and safety of saxagliptin versus placebo in Asian patients with type 2 diabetes mellitus (T2DM). Materials and Method
Publikováno v:
Diabetes Research and Clinical Practice. 94:217-224
Aim To assess efficacy and safety of saxagliptin added to metformin versus placebo plus metformin in Asian patients with type 2 diabetes mellitus (T2DM) and inadequate glycemic control on metformin alone. Methods Adults (HbA 1c 7.0–10.0%, on stable
Publikováno v:
Diabetes Therapy
Introduction Dapagliflozin is a first-in-class sodium-glucose transporter 2 (SGLT2) inhibitor under investigation for the treatment of type 2 diabetes mellitus. A thorough QTc study was conducted, according to International Conference on Harmonizatio
Publikováno v:
Diabetes and Vascular Disease Research. 4:214-221
This randomised, double-blind, parallel-group study assessed the effects of addition of the dual peroxisome proliferator-activated receptor (PPAR) α/γ agonist, tesaglitazar, for 24 weeks to the therapeutic regimen of 392 poorly controlled (glycosyl
Publikováno v:
Current Medical Research and Opinion. 22:2575-2590
The Glucose and Lipid Assessment in Diabetes (GLAD) trial examined the dose-response relationship of the dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist tesaglitazar in type 2 diabetic patients.GLAD was a 12-week, multicent
Autor:
Erin Morris, John S. Holcenberg, F. Leonard Johnson, Stanton Goldman, Raymond J. Hutchinson, Jerry Z. Finklestein, Susan G. Kreissman, Elizabeth Harvey, Conrad Tou, Mitchell S. Cairo
Publikováno v:
Blood. 97:2998-3003
Standard therapy in the United States for malignancy-associated hyperuricemia consists of hydration, alkalinization, and allopurinol. Urate oxidase catalyzes the enzymatic oxidation of uric acid to a 5 times increased urine soluble product, allantoin
Publikováno v:
Diabetes/metabolism research and reviews. 28(3)
Few studies have assessed the use of new oral anti-diabetic agents in Asian populations. This study assesses the efficacy and safety of saxagliptin versus placebo in Asian patients with type 2 diabetes mellitus (T2DM).Five hundred sixty-eight drug-na
Autor:
Rachel M. Frank, Howard Trachtman, Tej K. Matoo, Irene Restaino, Conrad Tou, John D. Mahan, Ronald J. Portman, Michael Klibaner
Publikováno v:
Pediatric nephrology (Berlin, Germany). 18(6)
Essential hypertension in pediatric patients may require pharmacological treatment. There is a need for efficacious, safe, and well-tolerated antihypertensive agents with a once-a-day dosing regimen in children and adolescents. The aim of the trial w
Autor:
W. Y. Tan, Conrad Tou
Publikováno v:
Biometrical Journal. 29:207-218
In this paper we consider a cell population such as bacteria consisting of two types of cells, mutant and nonmutant. Under the mutation and homogeneous pure birth processes, this paper derives a maximum likelihood estimation procedure for estimating