Molecular Interaction Network Approach (MINA) identifies association of novel candidate disease genes

Autor: Gerardo A. Pirela-Morillo, Conrad T. Gilliam, George S. Wilson, Sam Kara, Alaa Hanna

Publikováno v: MethodsX, Vol 6, Iss, Pp 1286-1291 (2019)

Molecular Interaction Network Approach (MINA) was used to elucidate candidate disease genes. The approach was implemented to identify novel gene association with commonly known autoimmune diseases [1]. In MINA, we evaluated the hypothesis that “net

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48fac00bff82772acb59e96f3bbb41f
https://doi.org/10.1016/j.mex.2019.05.031

Fine mapping of candidate regions for bipolar disorder provides strong evidence for susceptibility loci on chromosomes 7q

Autor: Rong Cheng, J E Loth, Jianjun Liu, Jean Endicott, Miron Baron, Conrad T. Gilliam, Suh-Hang Juo, Haiyan Xu

Publikováno v: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 156:168-176

Genomewide scans of bipolar disorder (BP) have not produced consistent linkage findings. Follow-up studies using enlarged samples and enhanced marker density can bolster or refute claims of linkage and pave the way to gene discovery. We conducted lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1397415bf252248895062366a76eedc
https://doi.org/10.1002/ajmg.b.31151

Genome Scan Meta-Analysis of Schizophrenia and Bipolar Disorder, Part III: Bipolar Disorder

Autor: J. Raymond DePaulo, Martin Alda, S H Juo, Philip B. Mitchell, Peter P. Zandi, Peter M. Visscher, Melvin G. McInnis, Johannes Schumacher, Michael Gill, Jenny Ekholm, Howard J. Edenberg, Stylianos E. Antonarakis, Nelson B. Freimer, Cathryn M. Lewis, Peter R. Schofield, Tatiana Foroud, Victor I. Reus, Jennifer A. Donald, Henrik Ewald, Takeo Yoshikawa, Conrad T. Gilliam, Rolf Adolfsson, Alison Goate, Theodore Reich, William Byerley, Elliot S. Gershon, Andrew McQuillin, Jouko Lönnqvist, Phil Bennett, Hugh Gurling, Paul Grof, Francis J. McMahon, Christine Windemuth, Judith A. Badner, L. J. Adams, John P. Rice, Wolfgang Maier, Michael Escamilla, Gursharan Kalsi, John I. Nurnberger, Douglas F. Levinson, Douglas Blackwood, Gustavo Turecki, Virginia L. Willour, Uppala Radhakrishna, Miron Baron, Hermann Luebbert, Jianjun Liu, Stuart MacGregor, Lynn R. Goldin, Eric Shink, Walter J. Muir, Pedro León, Torben A Kruse, Wade H. Berrettini, Nicholas John Craddock, Jurgen Del-Favero, John R. Kelsoe, Hilary Coon, Julien Mendlewicz, Sevilla D. Detera-Wadleigh, Jean-Louis Blouin, Leena Peltonen, Nurten A. Akarsu, Marcella Rietschel, Jean Morissette, Markus M. Nöthen, Christine Van Broeckhoven, M. Anne Spence, Peter Propping, Sven Cichon, Ole Mors, Nicholas Barden, Renee F. Badenhop, Stephan Claes, L. Alison McInnes, Ricardo Segurado, Guy A. Rouleau

Publikováno v: ResearcherID
American Journal of Human Genetics, Vol. 73, No 1 (2003) pp. 49-62

PUBLISHED
PMID: 12802785
Genome scans of bipolar disorder (BPD) have not produced consistent evidence for linkage. The rank-based genome scan meta-analysis (GSMA) method was applied to 18 BPD genome scan data sets in an effort to identify r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90680cf9fa645871cd26143366cb38a3

Noninvasive prenatal diagnosis of chromosomal aneuploidies by isolation and analysis of fetal cells from maternal blood

Autor: Haruo Takabayashi, Agata Grillo, Enrico Parano, Rosario R. Trifiletti, Conrad T. Gilliam, Ernesto Falcidia, Piero Pavone, Nunzio Cutuli

Publikováno v: American journal of medical genetics
info:cnr-pdr/source/autori:Parano, Enrico; Falcidia, Ernesto; Grillo, Agata; Pavone, Piero; Cutuli, Nunzio; Takabayashi, Haruo; Trífiletti, Rosario Rich; Gilliam, Thomas Conrad/titolo:Noninvasive prenatal diagnosis of chromosomal aneuploidies by isolation and analysis of fetal cells from maternal blood/doi:10.1002%2Fajmg.1350/rivista:American journal of medical genetics (Print)/anno:2001/pagina_da:262/pagina_a:267/intervallo_pagine:262–267/volume:101

The isolation and analysis of nucleated fetal cells (NFCs) from maternal blood may represent a new approach to noninvasive prenatal diagnosis. Although promising, these techniques require highly accurate separation of NFCs from nucleated cells of mat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff47c5492be751e22a8f0613a1a821f
http://www.cnr.it/prodotto/i/303509

N-terminal domains of human copper-transporting adenosine triphosphatases (the Wilson's and Menkes disease proteins) bind copper selectively in vivo and in vitro with stoichiometry of one copper per metal-binding repeat

Autor: Konstantin Petrukhin, Conrad T. Gilliam, Svetlana Lutsenko, Matthew J. Cooper, Jack H. Kaplan

Publikováno v: The Journal of biological chemistry. 272(30)

N-terminal domains of the Wilson's and Menkes disease proteins (N-WND and N-MNK) were overexpressed in a soluble form in Escherichia coli as fusions with maltose-binding protein, purified, and their metal-binding properties were characterized. Both N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a09b25b3c57a27fb33e63c1d17bf3d41
https://pubmed.ncbi.nlm.nih.gov/9228074