Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Conrad A. Nieduszynski"'
Autor:
Sean A. Bergin, Fang Zhao, Adam P. Ryan, Carolin A. Müller, Conrad A. Nieduszynski, Bing Zhai, Thierry Rolling, Tobias M. Hohl, Florent Morio, Jillian Scully, Kenneth H. Wolfe, Geraldine Butler
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT We analyzed the genomes of 170 C. parapsilosis isolates and identified multiple copy number variations (CNVs). We identified two genes, RTA3 (CPAR2_104610) and ARR3 (CPAR2_601050), each of which was the target of multiple independent amplifi
Externí odkaz:
https://doaj.org/article/bd920b5c016a49d6b688cd14f33c572d
Autor:
Pin Tong, Alison L. Pidoux, Nicholas R. T. Toda, Ryan Ard, Harald Berger, Manu Shukla, Jesus Torres-Garcia, Carolin A. Müller, Conrad A. Nieduszynski, Robin C. Allshire
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Although the centromere-specific histone CENP-A usually assembles on specific genomic sequences, centromeric DNA is not conserved. Here the authors characterize the genome and centromeres of related fission yeasts and provide evidence that Schizosacc
Externí odkaz:
https://doaj.org/article/2326eb1cb7ff4d129bd2996e9215ca50
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-4 (2019)
Abstract Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the
Externí odkaz:
https://doaj.org/article/f8ab45200bda4f0b979bdc8673945d1f
Publikováno v:
Wellcome Open Research, Vol 3 (2018)
Background: Understanding DNA replication initiation is essential to understand the mis-regulation of replication seen in cancer and other human disorders. DNA replication initiates from DNA replication origins. In eukaryotes, replication is dependen
Externí odkaz:
https://doaj.org/article/edf9d794fcfd4f9582ad6f98e450d126
Autor:
Michelle Hawkins, Renata Retkute, Carolin A. Müller, Nazan Saner, Tomoyuki U. Tanaka, Alessandro P.S. de Moura, Conrad A. Nieduszynski
Publikováno v:
Cell Reports, Vol 5, Iss 4, Pp 1132-1141 (2013)
Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution Saccharomyces cerevisiae genome replication data with a mathematical model allows quantificati
Externí odkaz:
https://doaj.org/article/0b8a803732cc4826adcb3dfb65f13b5c
Autor:
David S. Guttery, David J. P. Ferguson, Benoit Poulin, Zhengyao Xu, Ursula Straschil, Onny Klop, Lev Solyakov, Sara M. Sandrini, Declan Brady, Conrad A. Nieduszynski, Chris J. Janse, Anthony A. Holder, Andrew B. Tobin, Rita Tewari
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/96c334274b244aff8bfc9ba5647621ae
Autor:
Daniel Schindler, Roy S.K. Walker, Shuangying Jiang, Aaron N. Brooks, Yun Wang, Carolin A. Müller, Charlotte Cockram, Yisha Luo, Alicia García, Daniel Schraivogel, Julien Mozziconacci, Benjamin A. Blount, Jitong Cai, Lois Ogunlana, Wei Liu, Katarina Jönsson, Dariusz Abramczyk, Eva Garcia-Ruiz, Tomasz W. Turowski, Reem Swidah, Tom Ellis, Francisco Antequera, Yue Shen, Conrad A. Nieduszynski, Romain Koszul, Junbiao Dai, Lars M. Steinmetz, Jef D. Boeke, Yizhi Cai
Here we report the design, construction and characterization of a tRNA neochromosome, a designer chromosome that functions as an additional, de novo counterpart to the native complement of Saccharomyces cerevisiae. Intending to address one of the cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc49c630d11fb6cf58c3ffb12496ed73
https://doi.org/10.1101/2022.10.03.510608
https://doi.org/10.1101/2022.10.03.510608
Autor:
Sean A. Bergin, Fang Zhao, Adam P. Ryan, Carolin A. Müller, Conrad A. Nieduszynski, Bing Zhai, Thierry Rolling, Tobias M. Hohl, Florent Morio, Jillian Scully, Kenneth H. Wolfe, Geraldine Butler
Flippases and floppases are two classes of proteins that have opposing functions in the maintenance of lipid asymmetry of the plasma membrane. Flippases translocate lipids from the exoplasmic leaflet to the cytosolic leaflet, and floppases act in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ee4da03d20381ee3cb52cb6eac39146
https://doi.org/10.1101/2021.12.16.473093
https://doi.org/10.1101/2021.12.16.473093
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-4 (2019)
Genome Biology
Genome Biology
Recent studies have accomplished the extraordinary feat of measuring the exact status of DNA replication in individual cells. We outline how these studies have revealed surprising uniformity in how cells replicate their DNA, and consider the implicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e57ca842c56c02be04438d9987772f8
http://link.springer.com/article/10.1186/s13059-019-1719-y
http://link.springer.com/article/10.1186/s13059-019-1719-y
Publikováno v:
Physical Review E. 103
Cell plating, the spreading out of a liquid suspension of cells on a surface followed by colony growth, is a common laboratory procedure in microbiology. Despite this, the exact impact of its parameters on colony growth has not been extensively studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae66108aba1daeed9dd4af5889365e2
https://doi.org/10.1103/physreve.103.052410
https://doi.org/10.1103/physreve.103.052410