Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Conrad, von Schubert"'
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Expression of CD230 upon serum-starvation in parental and trisomic cells. Representative dot plots of FSC-A vs CD230-A for HCT116 parental and HCT116 trisomic clones - 18/3 cl2 and 21/3 cl1 and 3 - cultured under normal conditions (10% FBS, control)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eaa255ceb509dbfb703b0b818e3d11f
https://doi.org/10.1158/0008-5472.22413861
https://doi.org/10.1158/0008-5472.22413861
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Supplementary Tables S1-S3. Detailed description of antibodies used for the cell surface screenings performed with the initial 300 antibody high-throughput screening panel (S1), the 49-marker validation screening panel (S2), and the 36-marker mouse t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef5bcceba2a0a0efdc5a9761735bde2
https://doi.org/10.1158/0008-5472.22413855
https://doi.org/10.1158/0008-5472.22413855
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Description of the Supplementary Files
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ef92019852f7b871d7f010184ede3f
https://doi.org/10.1158/0008-5472.22413858
https://doi.org/10.1158/0008-5472.22413858
Autor:
Olaf Hardt, Zuzana Storchová, Andreas Bosio, Rocío Sotillo, Charles Swanton, Erich A. Nigg, Conrad von Schubert, Cristina Viganó, David Agorku, Sharavan V. Venkateswaran, Katarzyna Seget, Lalitha S.Y. Nanduri, Patrícia H. Domingues
Aneuploidy is a hallmark of most human tumors, but the molecular physiology of aneuploid cells is not well characterized. In this study, we screened cell surface biomarkers of approximately 300 proteins by multiparameter flow cytometry using multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6395c18abcc5710cf7f7ee01ff061457
https://doi.org/10.1158/0008-5472.c.6508839.v1
https://doi.org/10.1158/0008-5472.c.6508839.v1
Autor:
Conrad von Schubert, Fabien Cubizolles, Jasmine M. Bracher, Tale Sliedrecht, Geert J.P.L. Kops, Erich A. Nigg
Publikováno v:
Cell Reports, Vol 12, Iss 1, Pp 66-78 (2015)
Equal mitotic chromosome segregation is critical for genome integrity and is monitored by the spindle assembly checkpoint (SAC). We have previously shown that the consensus phosphorylation motif of the essential SAC kinase Monopolar spindle 1 (Mps1)
Externí odkaz:
https://doaj.org/article/6e114bcb298c4f418f1301462850b210
Autor:
Simon Imhof, Cristina Fragoso, Andrew Hemphill, Conrad von Schubert, Dong Li, Wesley Legant, Eric Betzig, Isabel Roditi
Publikováno v:
F1000Research, Vol 5 (2016)
Diverse structures facilitate direct exchange of proteins between cells, including plasmadesmata in plants and tunnelling nanotubes in bacteria and higher eukaryotes. Here we describe a new mechanism of protein transfer, flagellar membrane fusion, in
Externí odkaz:
https://doaj.org/article/0945cf0ee27c451c9788cebd64cdb028
Autor:
Anna P Baron, Conrad von Schubert, Fabien Cubizolles, Gerhard Siemeister, Marion Hitchcock, Anne Mengel, Jens Schröder, Amaury Fernández-Montalván, Franz von Nussbaum, Dominik Mumberg, Erich A Nigg
Publikováno v:
eLife, Vol 5 (2016)
The kinase Bub1 functions in the spindle assembly checkpoint (SAC) and in chromosome congression, but the role of its catalytic activity remains controversial. Here, we use two novel Bub1 inhibitors, BAY-320 and BAY-524, to demonstrate potent Bub1 ki
Externí odkaz:
https://doaj.org/article/6034c6d2d52a45f79491d203cc2e6f03
Autor:
Olga Wiens, Dong Xia, Conrad von Schubert, Jonathan M Wastling, Dirk A E Dobbelaere, Volker T Heussler, Kerry L Woods
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103821 (2014)
The invasion of Theileria sporozoites into bovine leukocytes is rapidly followed by the destruction of the surrounding host cell membrane, allowing the parasite to establish its niche within the host cell cytoplasm. Theileria infection induces host c
Externí odkaz:
https://doaj.org/article/2b1cc152fbef4b889c92a46fa0612fab
Autor:
Erich A. Nigg, Zuzana Storchova, Alexander Schmidt, Guido J.R. Zaman, Lukas Bubendorf, Judith R.F. de Vetter, Erik Ahrné, Cristina Viganó, Conrad von Schubert, Thomas Lorber
Publikováno v:
Molecular Biology of the Cell
This study analyzes the proteomes and phospho-proteomes of isogenic DLD-1 cancer cells differing in karyotypes and chromosome stability. Chromosome doubling is shown to trigger more extensive changes in (phospho-)proteomes than chromosome instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76548d007ebdb7ecc323391c868b3e91
https://doi.org/10.1091/mbc.e17-10-0577
https://doi.org/10.1091/mbc.e17-10-0577
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18793 (2011)
BACKGROUND: Members of the Mps1 kinase family play an essential and evolutionarily conserved role in the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures accurate chromosome segregation during mitosis. Human Mps1 (hMps1) is hi
Externí odkaz:
https://doaj.org/article/0e362e332b5e4d3bb45fcdb19fe47f9b