Zobrazeno 1 - 10
of 960
pro vyhledávání: '"Conrad, C. P."'
Autor:
Michio Inoue, Divya Jayaraman, Rocio Bengoechea, Ankan Bhadra, Casie A. Genetti, Abdulrahman A. Aldeeri, Betül Turan, Rafael Adrian Pacheco-Orozco, Almundher Al-Maawali, Nadia Al Hashmi, Ayşe Gül Zamani, Emine Göktaş, Sevgi Pekcan, Hanife Tuğçe Çağlar, Heather True, Alan H. Beggs, Conrad C. Weihl
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Protein aggregate myopathies can result from pathogenic variants in genes encoding protein chaperones. DNAJB4 is a cochaperone belonging to the heat shock protein-40 (HSP40) family and plays a vital role in cellular proteostasis. Recessive l
Externí odkaz:
https://doaj.org/article/e80b65429e294678b2ab23a55f25523b
Autor:
Shruthi Mohan, Shannon McNulty, Courtney Thaxton, Marwa Elnagheeb, Emma Owens, May Flowers, Teagan Nunnery, Autumn Self, Brooke Palus, Svetlana Gorokhova, April Kennedy, Zhiyv Niu, Mridul Johari, Alassane Baneye Maiga, Kelly Macalalad, Amanda R. Clause, Jacques S. Beckmann, Lucas Bronicki, Sandra T. Cooper, Vijay S. Ganesh, Peter B. Kang, Akanchha Kesari, Monkol Lek, Jennifer Levy, Laura Rufibach, Marco Savarese, Melissa J. Spencer, Volker Straub, Giorgio Tasca, Conrad C. Weihl
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 9, Pp 2268-2276 (2024)
Abstract Objective Limb girdle muscular dystrophies (LGMDs) are a group of genetically heterogeneous autosomal conditions with some degree of phenotypic homogeneity. LGMD is defined as having onset >2 years of age with progressive proximal weakness,
Externí odkaz:
https://doaj.org/article/d476e18b181c4fa5a1595ad8584a2ce4
Autor:
Richard J. Knecht, Jacob S. Benner, Anshuman Swain, Lauren Azevedo-Schmidt, Christopher J. Cleal, Conrad C. Labandeira, Michael S. Engel, Jason A. Dunlop, Paul A. Selden, Cortland F. Eble, Mark D. Renczkowski, Dillon A. Wheeler, Mataeus M. Funderburk, Steve L. Emma, Andrew H. Knoll, Naomi E. Pierce
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Much of what we know about terrestrial life during the Carboniferous Period comes from Middle Pennsylvanian (~315–307 Mya) Coal Measures deposited in low-lying wetland environments1–5. We know relatively little about terrestrial ecosyste
Externí odkaz:
https://doaj.org/article/3db49f3aab1e49ff9f16c66fe22a47ea
Autor:
Amy Doody, Lindsay Alfano, Jordi Diaz-Manera, Linda Lowes, Tahseen Mozaffar, Katherine D. Mathews, Conrad C. Weihl, Matthew Wicklund, Man Hung, Jeffrey Statland, Nicholas E. Johnson, On behalf of the GRASP-LGMD Consortium
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background The Limb Girdle Muscular Dystrophies (LGMDs) are characterized by progressive weakness of the shoulder and hip girdle muscles as a result of over 30 different genetic mutations. This study is designed to develop clinical outcome a
Externí odkaz:
https://doaj.org/article/c61603f586d34df6b7a34a1f86705733
Autor:
Ankita Sharma, Sukhleen Kaur, Abubakar Wani, Dilpreet Kour, Mehboob Ali, Syed Mudassir Ali, Lakhvinder Singh, Abhishek Gour, Utpal Nandi, Manish Datt, Parduman Raj Sharma, Conrad C Weihl, Gurdarshan Singh, Ajay Kumar
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
ABSTRACTBeing present in substantial numbers, astrocytes play an indispensable role in maintaining homeostasis in the brain. However, their positive or negative involvement in pathological conditions in the brain has not been explored much. In recent
Externí odkaz:
https://doaj.org/article/25c78f4100fa46be8e209b6d79865ea0
Autor:
Hui Jiang, Jacek Szwedo, Conrad C. Labandeira, Jun Chen, Maxwell S. Moulds, Bastian Mähler, A. Drew Muscente, De Zhuo, Thet Tin Nyunt, Haichun Zhang, Cong Wei, Jes Rust, Bo Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Extant cicada (Hemiptera: Cicadoidea) includes widely distributed Cicadidae and relictual Tettigarctidae, with fossils ascribed to these two groups based on several distinct, minimally varying morphological differences that define their exta
Externí odkaz:
https://doaj.org/article/5670fd5e653b4b7a817601b87573a097
Autor:
Thamiris Barbosa Dos Santos, Conrad C. Labandeira, Esther Regina de Souza Pinheiro, Roberto Iannuzzi
Publikováno v:
Frontiers in Ecology and Evolution, Vol 12 (2024)
IntroductionThe Sanzenbacher Ranch deposit represents an early Permian plant assemblage in north-central Texas predominantly composed of pteridosperms, of which callipterids are dominant. This study investigates the interactions of a taxonomically br
Externí odkaz:
https://doaj.org/article/cc3fc2fa9da64f15911a19d4181b6f36
Autor:
Shilong Guo, Wang Ma, Yunyu Tang, Liang Chen, Ying Wang, Yingying Cui, Junhui Liang, Longfeng Li, Jialiang Zhuang, Junjie Gu, Mengfei Li, Hui Fang, Xiaodan Lin, Chungkun Shih, Conrad C. Labandeira, Dong Ren
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Currently, studies of ancient faunal community networks have been based mostly on uniformitarian and functional morphological evidence. As an important source of data, taphonomic evidence offers the opportunity to provide a broader scope for
Externí odkaz:
https://doaj.org/article/cdfaeea60b4248c3aa64d7a3ea4e48c1
Autor:
Andrew R. Findlay, May M. Paing, Jil A. Daw, Meade Haller, Rocio Bengoechea, Sara K. Pittman, Shan Li, Feng Wang, Timothy M. Miller, Heather L. True, Tsui-Fen Chou, Conrad C. Weihl
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 937-948 (2023)
Dominant missense mutations in DNAJB6, a co-chaperone of HSP70, cause limb girdle muscular dystrophy (LGMD) D1. No treatments are currently available. Two isoforms exist, DNAJB6a and DNAJB6b, each with distinct localizations in muscle. Mutations resi
Externí odkaz:
https://doaj.org/article/98875bfcbb0241d7a450adbfdbc2b0b5
Autor:
Stern, S. A., Weaver, H. A., Spencer, J. R., Olkin, C. B., Gladstone, G. R., Grundy, W. M., Moore, J. M., Cruikshank, D. P., Elliott, H. A., McKinnon, W. B., Parker, J. Wm., Verbiscer, A. J., Young, L. A., Aguilar, D. A., Albers, J. M., Andert, T., Andrews, J. P., Bagenal, F., Banks, M. E., Bauer, B. A., Bauman, J. A., Bechtold, K. E., Beddingfield, C. B., Behrooz, N., Beisser, K. B., Benecchi, S. D., Bernardoni, E., Beyer, R. A., Bhaskaran, S., Bierson, C. J., Binzel, R. P., Birath, E. M., Bird, M. K., Boone, D. R., Bowman, A. F., Bray, V. J., Britt, D. T., Brown, L. E., Buckley, M. R., Buie, M. W., Buratti, B. J., Burke, L. M., Bushman, S. S., Carcich, B., Chaikin, A. L., Chavez, C. L., Cheng, A. F., Colwell, E. J., Conard, S. J., Conner, M. P., Conrad, C. A., Cook, J. C., Cooper, S. B., Custodio, O. S., Ore, C. M. Dalle, Deboy, C. C., Dharmavaram, P., Dhingra, R. D., Dunn, G. F., Earle, A. M., Egan, A. F., Eisig, J., El-Maarry, M. R., Engelbrecht, C., Enke, B. L., Ercol, C. J., Fattig, E. D., Ferrell, C. L., Finley, T. J., Firer, J., Fischetti, J., Folkner, W. M., Fosbury, M. N., Fountain, G. H., Freeze, J. M., Gabasova, L., Glaze, L. S., Green, J. L., Griffith, G. A., Guo, Y., Hahn, M., Hals, D. W., Hamilton, D. P., Hamilton, S. A., Hanley, J. J., Harch, A., Harmon, K. A., Hart, H. M., Hayes, J., Hersman, C. B., Hill, M. E., Hill, T. A., Hofgartner, J. D., Holdridge, M. E., Horányi, M., Hosadurga, A., Howard, A. D., Howett, C. J. A., Jaskulek, S. E., Jennings, D. E., Jensen, J. R., Jones, M. R., Kang, H. K., Katz, D. J., Kaufmann, D. E., Kavelaars, J. J., Keane, J. T., Keleher, G. P., Kinczyk, M., Kochte, M. C., Kollmann, P., Krimigis, S. M., Kruizinga, G. L., Kusnierkiewicz, D. Y., Lahr, M. S., Lauer, T. R., Lawrence, G. B., Lee, J. E., Lessac-Chenen, E. J., Linscott, I. R., Lisse, C. M., Lunsford, A. W., Mages, D. M., Mallder, V. A., Martin, N. P., May, B. H., McComas, D. J., McNutt, R. L., Mehoke, Jr. D. S., Mehoke, T. S., Nelson, D. S., Nguyen, H. D., Núñez, J. I., Ocampo, A. C., Owen, W. M., Oxton, G. K., Parker, A. H., Pätzold, M., Pelgrift, J. Y., Pelletier, F. J., Pineau, J. P., Piquette, M. R., Porter, S. B., Protopapa, S., Quirico, E., Redfern, J. A., Regiec, A. L., Reitsema, H. J., Reuter, D. C., Richardson, D. C., Riedel, J. E., Ritterbush, M. A., Robbins, S. J., Rodgers, D. J., Rogers, G. D., Rose, D. M., Rosendall, P. E., Runyon, K. D., Ryschkewitsch, M. G., Saina, M. M., Salinas, M. J., Schenk, P. M., Scherrer, J. R., Schlei, W. R., Schmitt, B., Schultz, D. J., Schurr, D. C., Scipioni, F., Sepan, R. L., Shelton, R. G., Showalter, M. R., Simon, M., Singer, K. N., Stahlheber, E. W., Stanbridge, D. R., Stansberry, J. A., Steffl, A. J., Strobel, D. F., Stothoff, M. M., Stryk, T., Stuart, J. R., Summers, M. E., Tapley, M. B., Taylor, A., Taylor, H. W., Tedford, R. M., Throop, H. B., Turner, L. S., Umurhan, O. M., Van Eck, J., Velez, D., Versteeg, M. H., Vincent, M. A., Webbert, R. W., Weidner, S. E., Weigle II, G. E., Wendel, J. R., White, O. L., Whittenburg, K. E., Williams, B. G., Williams, K. E., Williams, S. P., Winters, H. L., Zangari, A. M., Zurbuchen, T. H.
Publikováno v:
Science 364, eaaw9771 (2019)
The Kuiper Belt is a distant region of the Solar System. On 1 January 2019, the New Horizons spacecraft flew close to (486958) 2014 MU69, a Cold Classical Kuiper Belt Object, a class of objects that have never been heated by the Sun and are therefore
Externí odkaz:
http://arxiv.org/abs/2004.01017
