Výsledky vyhledávání - "Conor W Templeton"

Akademický článek

HPV induced R-loop formation represses innate immune gene expression while activating DNA damage repair pathways.

Autor: Conor W Templeton, Laimonis A Laimins

Publikováno v: PLoS Pathogens, Vol 20, Iss 8, p e1012454 (2024)

R-loops are trimeric nucleic acid structures that form when an RNA molecule hybridizes with its complementary DNA strand, displacing the opposite strand. These structures regulate transcription as well as replication, but aberrant R-loops can form, l

Externí odkaz: https://doaj.org/article/5c3cc9ae4fbe4f00bf322ffec4700fdb

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UV Irradiation of Vaccinia Virus-Infected Cells Impairs Cellular Functions, Introduces Lesions into the Viral Genome, and Uncovers Repair Capabilities for the Viral Replication Machinery

Autor: Conor W. Templeton, Paula Traktman

Publikováno v: J Virol

Vaccinia virus (VV), the prototypic poxvirus, encodes a repertoire of proteins responsible for the metabolism of its large dsDNA genome. Previous work has furthered our understanding of how poxviruses replicate and recombine their genomes, but little

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee8322856dff0aa3e4da530c482a58e
https://doi.org/10.1128/jvi.02137-21

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