The role of stress and stress adaptations in determining the fate of the bacterial pathogen Listeria monocytogenes in the food chain.

Autor: Kerrie NicAogain, Conor P O'Byrne

Publikováno v: Frontiers in Microbiology, Vol 7 (2016)

The foodborne pathogen L. monocytogenes is a highly adaptable organism that can persist in a wide range of environmental and food-related niches. The consumption of contaminated ready-to-eat (RTE) foods can cause infections, termed listeriosis, in vu

Externí odkaz: https://doaj.org/article/91470bc873eb4ac0807dbb5be6a1d708

A single point mutation in the Listeria monocytogenes ribosomal gene rpsU enables SigB activation independently of the stressosome and the anti-sigma factor antagonist RsbV

Autor: Xuchuan Ma, Marcel H. Tempelaars, Marcel H. Zwietering, Sjef Boeren, Conor P. O’Byrne, Heidy M. W. den Besten, Tjakko Abee

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

Microbial population heterogeneity leads to different stress responses and growth behavior of individual cells in a population. Previously, a point mutation in the rpsU gene (rpsUG50C) encoding ribosomal protein S21 was identified in a Listeria monoc

Externí odkaz: https://doaj.org/article/4441ef3782c74f6e84b8f01556024a3e

The stressosome is required to transduce low pH signals leading to increased transcription of the amino acid-based acid tolerance mechanisms in Listeria monocytogenes

Autor: Duarte N. Guerreiro, Aoife Boyd, Conor P. O'Byrne

Publikováno v: Access Microbiology. 4

Increasing proton concentration in the environment represents a potentially lethal stress for single-celled microorganisms. To survive in an acidifying environment, the foodborne pathogen Listeria monocytogenes quickly activates the alternative sigma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::73c86844077ece5a3dbc595c759a4dc8
https://doi.org/10.1099/acmi.0.000455

In Vitro Evolution of Listeria monocytogenes Reveals Selective Pressure for Loss of SigB and AgrA Function at Different Incubation Temperatures

Autor: Duarte N. Guerreiro, Jialun Wu, Emma McDermott, Dominique Garmyn, Peter Dockery, Aoife Boyd, Pascal Piveteau, Conor P. O’Byrne

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, 2022, 88 (11), 17p. ⟨10.1128/aem.00330-22⟩
Appl Environ Microbiol

The alternative sigma factor B (σ(B)) contributes to the stress tolerance of the foodborne pathogen Listeria monocytogenes by upregulating the general stress response. We previously showed that σ(B) loss-of-function mutations arise frequently in st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eabe0d028a859b883418c16d762bc9a
https://doi.org/10.1128/aem.00330-22

Listeria monocytogenes requires the RsbX protein to prevent SigB-activation under non-stressed conditions

Autor: Hasan Tükenmez, Ana H. Oliveira, Duarte N. Guerreiro, Francisco García-del Portillo, Jörgen Johansson, Charlotte Dessaux, Teresa Tiensuu, Conor P. O'Byrne

Publikováno v: Journal of Bacteriology

The survival of microbial cells under changing environmental conditions requires an efficient reprogramming of transcription, often mediated by alternative sigma factors. The Gram-positive human pathogen Listeria monocytogenes senses and responds to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc13fd181373e6da5e8679ea407e575b
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-190844