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Autor:
Conor Mullaney, Yi Wang, Krista Johnson, Eric D. Lombardini, Paul P. Tamburini, Jeremy P. Springhorn, Patrick H. Ney, Merriline M. Satyamitra, John Graves, Venkataraman Srinivasan, Jeffrey W. Hunter
Publikováno v:
Radiation research. 175(6)
Thrombopoietin (TPO) receptor agonists lacking sequence homology to TPO were designed by grafting a known peptide sequence into the hinge and/or kappa constant regions of a human anti-anthrax antibody. Some of these proteins were equipotent to TPO in