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Publikováno v:
Journal of inorganic biochemistry. 234
A novel Trojan Horse conjugate consisting of an SO
Publikováno v:
Journal of Inorganic Biochemistry. 234:111875
Publikováno v:
ChemMedChem. 16(7)
The field of antibacterial siderophore conjugates, referred to as Trojan Horse antibacterials, has received increasing attention in recent years, driven by the rise of antimicrobial resistance. Trojan Horse antibacterials offer an opportunity to expl
Autor:
Eszter Boros, Ellis J. Wilde, Anne Routledge, Conor M. Black, Anne-Kathrin Duhme-Klair, Apurva Pandey, James W. Southwell, Reyme Herman, Gavin H. Thomas, Thomas J. Sanderson
A novel ciprofloxacin-siderophore Trojan Horse antimicrobial was prepared by incorporating key design features of salmochelin S4, a stealth siderophore that evades mammalian siderocalin capture via its glycosylated catechol units. As-sessment of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72fb5caca9fe56330a2161a740d53d39
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf
https://eprints.whiterose.ac.uk/164830/8/acsinfecdis.0c00568.pdf
Difluoromethyl ketones are an under-studied class of ketones which have great potential as useful building blocks for materials and drug design. Here we report a simple and convenient synthesis of this class of compounds via a one-pot difluorination/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::855a672f48afdbe5c942aa96348755f1
http://wrap.warwick.ac.uk/75788/1/WRAP_Leng_1270619-institute_of_advanced_accepted_manuscript.pdf
http://wrap.warwick.ac.uk/75788/1/WRAP_Leng_1270619-institute_of_advanced_accepted_manuscript.pdf