Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Conor M, Ramsden"'
Autor:
Karen Eastlake, Weixin Wang, Hari Jayaram, Celia Murray‐Dunning, Amanda J. F. Carr, Conor M. Ramsden, Anthony Vugler, Katrina Gore, Nadine Clemo, Mark Stewart, Pete Coffey, Peng T. Khaw, G. Astrid Limb
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 775-784 (2019)
Abstract Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to pro
Externí odkaz:
https://doaj.org/article/3318628640d742c6b2a42b2b510967aa
Autor:
Conor M. Ramsden, Britta Nommiste, Amelia R. Lane, Amanda-Jayne F. Carr, Michael B. Powner, Matthew J. K. Smart, Li Li Chen, Manickam N. Muthiah, Andrew R. Webster, Anthony T. Moore, Michael E. Cheetham, Lyndon da Cruz, Peter J. Coffey
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Inherited retinal dystrophies are an important cause of blindness, for which currently there are no effective treatments. In order to study this heterogeneous group of diseases, adequate disease models are required in order to better underst
Externí odkaz:
https://doaj.org/article/2c6bb3edda1a42e7b46f27b3e51b9e86
Autor:
Camille Yvon, Conor M. Ramsden, Amelia Lane, Michael B. Powner, Lyndon da Cruz, Peter J. Coffey, Amanda-Jayne F. Carr
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 382-389 (2015)
Retinal degeneration arises from the loss of photoreceptors or retinal pigment epithelium (RPE). It is one of the leading causes of irreversible blindness worldwide with limited effective treatment options. Generation of induced pluripotent stem cell
Externí odkaz:
https://doaj.org/article/4848c3dce7664794b6915626e083733e
Autor:
Ceniz Zihni, Anastasios Georgiadis, Conor M. Ramsden, Elena Sanchez-Heras, Alexis J. Haas, Britta Nommiste, Olha Semenyuk, James W.B. Bainbridge, Peter J. Coffey, Alexander J. Smith, Robin R. Ali, Maria S. Balda, Karl Matter
Publikováno v:
Journal of Cell Biology. 221
Phagocytosis requires actin dynamics, but whether actomyosin contractility plays a role in this morphodynamic process is unclear. Here, we show that in the retinal pigment epithelium (RPE), particle binding to Mer Tyrosine Kinase (MerTK), a widely ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6449d9e0ea2a1ea45fbbcae2e1bc562c
https://doi.org/10.1083/jcb.202012042
https://doi.org/10.1083/jcb.202012042
Autor:
Ronan A. Cahill, David J Keegan, Manjit Mehat, Louise O’Toole, Louisa Wickham, Kevin Nolan, Conor M. Ramsden, Nicholas Brennan, Rodrigo Anguita
Publikováno v:
European journal of ophthalmology. 32(4)
Objective: To assess the patterns of patient generated aerosol in the context of ophthalmic surgery and ophthalmic examinations. To inform medical teams regarding potential hazards and suggest mitigating measures. Methods: Qualitatively, real-time ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c499ecd54d5a0754a33fe34549cb63
https://pubmed.ncbi.nlm.nih.gov/34392739
https://pubmed.ncbi.nlm.nih.gov/34392739
Autor:
Peter J. Coffey, Conor M. Ramsden, Weixin Wang, Nadine Clemo, Hari Jayaram, Peng T. Khaw, Amanda J. F. Carr, Katrina Gore, G. Astrid Limb, Anthony Vugler, Karen Eastlake, Mark Stewart, Celia Murray-Dunning
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 8, Pp 775-784 (2019)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Glaucoma is one of the leading causes of blindness, and there is an ongoing need for new therapies. Recent studies indicate that cell transplantation using Müller glia may be beneficial, but there is a need for novel sources of cells to provide ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950a071e65b6d1527e856048b5517115
https://doi.org/10.1002/sctm.18-0263
https://doi.org/10.1002/sctm.18-0263
Autor:
Ceniz Zihni, Peter J. Coffey, Conor M. Ramsden, Elena Sanchez-Heras, Britta Nommiste, Alexander J. Smith, James W B Bainbridge, Anastasios Georgiadis, Robin R. Ali, Maria S. Balda, Karl Matter, Olha Semenyuk
SUMMARYPhagocytosis requires myosin-generated contractile force to regulate actin dynamics. However, little is known about the molecular mechanisms that guide this complex morphodynamic process. Here we show that particle binding to Mer Tyrosine Kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e978382467f7dcb4ca75e83c3886585
https://doi.org/10.1101/2021.03.25.436833
https://doi.org/10.1101/2021.03.25.436833
Publikováno v:
Eye. 36:1510-1511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70218111eb981ff39c17ed85b0e830f5
https://doi.org/10.1038/s41433-021-01695-8
https://doi.org/10.1038/s41433-021-01695-8
Autor:
Ahmad Ahmado, Anthony A. Vugler, Paul J. Whiting, Sakina B Gooljar, Lyndon da Cruz, Tricia Harbinson, Adnan Tufail, Conor M. Ramsden, Anna Wilbrey, Amanda J. Vernon, Mark Whitlock, Kate Fynes, Julie Kerby, Odysseas Georgiadis, Juliette Steer, Mandeep S. Sagoo, Magda Bictash, Peter J. Coffey, Amanda-Jayne F. Carr, Shazeen M Hasan, Yvonne Hsu-Lin Luo, Mike Fenster, Britta Nommiste, Graham E. Holder, Anthony G. Robson, Peter T. Loudon, Julie T. Daniels, Gang Feng
Publikováno v:
Nature Biotechnology. 36:328-337
Age-related macular degeneration (AMD) remains a major cause of blindness, with dysfunction and loss of retinal pigment epithelium (RPE) central to disease progression. We engineered an RPE patch comprising a fully differentiated, human embryonic ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d2e004d8a57eadf8ae9553a3d492e47
https://doi.org/10.1038/nbt.4114
https://doi.org/10.1038/nbt.4114
Autor:
Rosalina Naidoo, Sajir Mohamedbhai, Huw Richards, Elizabeth Jacob, Conor M. Ramsden, Camille Yvon
Publikováno v:
Expert Review of Ophthalmology. 12:133-148
Introduction: Lymphoma is the commonest malignancy of the ocular adnexa. Its relatively low incidence and significant heterogeneity pose unique clinical, diagnostic and therapeutic challenges, requiring a multidisciplinary approach to its management.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a62c9497f7b8aafdd47e113523a4a1
https://doi.org/10.1080/17469899.2017.1280394
https://doi.org/10.1080/17469899.2017.1280394