Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Conor J. Crawford"'
Autor:
Conor J. Crawford, Lorenzo Guazzelli, Scott A. McConnell, Orla McCabe, Clotilde d'Errico, Seth Greengo, Maggie P. Wear, Anne J. Jedlicka, Arturo Casadevall, Stefan Oscarson
Antibodies play critical roles in protection against infectious diseases and can be passively administered to protect patients. In the case of antibodies against glucuronoxylomannan (GXM), the major constituent of the Cryptococcus neoformans capsule,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf7bbffee57647075674c361a88db0b5
https://doi.org/10.26434/chemrxiv-2023-nm09n
https://doi.org/10.26434/chemrxiv-2023-nm09n
Autor:
Maggie P. Wear, Audra A. Hargett, John E. Kelly, Scott A. McConnell, Darón I. Freedberg, Arturo Casadevall, Conor J. Crawford, Ruth E. Stark
Publikováno v:
The FASEB Journal. 36
Autor:
Maggie P. Wear, Audra A. Hargett, John E. Kelly, Scott A. McConnell, Conor J. Crawford, Darón I. Freedberg, Ruth E. Stark, Arturo Casadevall
Publikováno v:
Carbohydrate polymers. 291
Microbial polysaccharide characterization requires purification that often involves detergent precipitation and lyophilization. Here we examined physicochemical changes following lyophilization of Cryptococcus neoformans exopolysaccharide (EPS). Solu
Autor:
Maggie P. Wear, Audra A. Hargett, John E. Kelly, Scott A. McConnell, Conor J. Crawford, Darón I. Freedberg, Ruth E. Stark, Arturo Casadevall
The structural, antigenic, and immunological characterization of microbial polysaccharides requires purification that often involves detergent precipitation and lyophilization. Here we examine physicochemical changes induced by lyophilization on exop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399f307a9372de1b3b67517d9c104636
https://doi.org/10.1101/2022.03.04.483041
https://doi.org/10.1101/2022.03.04.483041
Autor:
Conor J. Crawford, Stefan Oscarson
Publikováno v:
European Journal of Organic Chemistry. 2020:3332-3337
Autor:
Anthony Bowen, Maggie P. Wear, Arturo Casadevall, Radames J. B. Cordero, Stefan Oscarson, Conor J. Crawford, Lorenzo Guazzelli
Publikováno v:
Journal of Biological Chemistry. 295:4327-4340
Chemical biology is an emerging field that enables the study and manipulation of biological systems with probes whose reactivities provide structural insights. The opportunistic fungal pathogen Cryptococcus neoformans possesses a polysaccharide capsu
Autor:
Rebecca Ulc, Conor J. Crawford, Anthony Bowen, Orla McCabe, Maggie P. Wear, Arturo Casadevall, Lorenzo Guazzelli, Stefan Oscarson, Anne J. Jedlicka
Publikováno v:
Chemical Science
A convergent synthetic strategy to Cryptococcus neoformans glucuronoxylomannan (GXM) capsular polysaccharide part structures was developed based on di-, tri-, tetra-, penta- and hexasaccharide thioglycoside building blocks. The approach permitted the
Autor:
Vipul Solanki, Karen Krüger, Conor J. Crawford, Alonso Pardo-Vargas, José Danglad-Flores, Kim Le Mai Hoang, Leeann Klassen, D. Wade Abbott, Peter H. Seeberger, Rudolf I. Amann, Hanno Teeling, Jan-Hendrik Hehemann
Publikováno v:
The ISME Journal
The ISME journal 16(7), 1818-1830 (2022). doi:10.1038/s41396-022-01223-w
Seminar, Bremen, Germany
The ISME journal 16(7), 1818-1830 (2022). doi:10.1038/s41396-022-01223-w
Seminar, Bremen, Germany
Seminar, Bremen, Germany; The ISME journal 16(7), 1818 - 1830 (2022). doi:10.1038/s41396-022-01223-w
Microbial glycan degradation is essential to global carbon cycling. The marine bacterium Salegentibacter sp. Hel_I_6 (Bacteroidota) isolated fro
Microbial glycan degradation is essential to global carbon cycling. The marine bacterium Salegentibacter sp. Hel_I_6 (Bacteroidota) isolated fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bd3aa2682dc70e3247f6654b0542350
https://hdl.handle.net/21.11116/0000-000A-A00D-321.11116/0000-000A-5FFE-F
https://hdl.handle.net/21.11116/0000-000A-A00D-321.11116/0000-000A-5FFE-F
Cryptococcus neoformans capsule regrowth experiments reveal dynamics of enlargement and architecture
Autor:
Maggie P. Wear, Ella Jacobs, Siqing Wang, Scott A. McConnell, Anthony Bowen, Camilla Strother, Radames J.B. Cordero, Conor J. Crawford, Arturo Casadevall
Publikováno v:
The Journal of biological chemistry. 298(4)
The polysaccharide capsule of fungal pathogen Cryptococcus neoformans is a critical virulence factor that has historically evaded complete characterization. Cryptococcal polysaccharides are known to either remain attached to the cell as capsular poly
Autor:
Conor J. Crawford, Daniel F Q Smith, Maggie P. Wear, Stefan Oscarson, Scott A McConnell, Clotilde d’Errico, Arturo Casadevall
Publikováno v:
Proc Natl Acad Sci U S A
Classical antibody functions include opsonization, complement activation, and enhancement of cellular antimicrobial function. Antibodies can also have catalytic activity, although the contribution of catalysis to their biological functions has been m