Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Conor D, Tweed"'
Autor:
Kate Sturgeon, Ali Judd, Tom Burke, Caroline Foster, Diana M. Gibb, Marthe Le Prevost, Warren Mhizha, Conor D. Tweed
Publikováno v:
Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Background The Adolescents and Adults Living with Perinatal HIV (AALPHI) study is one of only three cohort studies worldwide evaluating the impact of HIV on young people living with perinatal HIV (PLHIV) relative to a comparable group of HIV
Externí odkaz:
https://doaj.org/article/03a52efb337a4ec1924809e820f3624c
Autor:
Annabelle South, Parveen Dhesi, Conor D. Tweed, Bazarragchaa Tsogt, Suzanne Staples, Nestani Tukvadze, Gantsetseg Dorj, Sindisiwe Zaca, Ekaterine Sanikidze, Nasanjargal Purev, Hanif Esmail, Rochelle Burgess
Publikováno v:
Global Public Health, Vol 18, Iss 1 (2023)
We conducted qualitative research exploring the treatment experience of people with DR-TB. We held nine focus group discussions with 57 adults undergoing/recently completed treatment for DR-TB in Georgia, Mongolia and South Africa. Translated transcr
Externí odkaz:
https://doaj.org/article/33df2b5709b144119bc50da3b0d53c34
Autor:
Emily C. Pickering, Bec Hanley, Philip Bell, Jacqui Gath, Patrick Hanlon, Robert Oldroyd, Richard Stephens, Conor D. Tweed
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-12 (2021)
Plain English summary Clinical Trials Units are encouraged to integrate Patient and Public Involvement (PPI) into all aspects of their trials. This research explored the induction and training of PPI Contributors (e.g. patients, carers and members of
Externí odkaz:
https://doaj.org/article/5182adaced6c4251bb7f0fc3ef87e17f
Autor:
Brennan C. Kahan, Tim P. Morris, Ian R. White, Conor D. Tweed, Suzie Cro, Darren Dahly, Tra My Pham, Hanif Esmail, Abdel Babiker, James R. Carpenter
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract When designing a clinical trial, explicitly defining the treatment estimands of interest (that which is to be estimated) can help to clarify trial objectives and ensure the questions being addressed by the trial are clinically meaningful. Th
Externí odkaz:
https://doaj.org/article/e989979a7315477483dd2291e0106e75
Autor:
Conor D. Tweed, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Lerato Mohapi, Michael E. Murphy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Stephen H. Gillespie
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure rates according to H
Externí odkaz:
https://doaj.org/article/d4f6503cd6b943dbb18e73105c9b0eb8
Autor:
Conor D. Tweed, Angela M. Crook, Evans I. Amukoye, Rodney Dawson, Andreas H. Diacon, Madeline Hanekom, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Michael E. Murphy, Saraswathi E. Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Genevieve H. Wills, Stephen H. Gillespie
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the standard regimen and two
Externí odkaz:
https://doaj.org/article/87ffe9cc14bf494197dd9d05a700110f
Autor:
Rebecca M. Turner, Michelle N. Clements, Matteo Quartagno, Victoria Cornelius, Suzie Cro, Deborah Ford, Conor D. Tweed, A. Sarah Walker, Ian R. White
Bayesian analysis of a non-inferiority trial is advantageous in allowing direct probability statements to be made about the relative treatment difference rather than relying on an arbitrary and often poorly justified non-inferiority margin. When the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc87bd22c0d077e6905efec7288d579c
http://hdl.handle.net/10044/1/101829
http://hdl.handle.net/10044/1/101829
Autor:
Tra My Pham, Conor D Tweed, James R Carpenter, Brennan C Kahan, Andrew J Nunn, Angela M Crook, Hanif Esmail, Ruth Goodall, Patrick PJ Phillips, Ian R White
Publikováno v:
Clinical trials (London, England), vol 19, iss 5
Background/aims Tuberculosis remains one of the leading causes of death from an infectious disease globally. Both choices of outcome definitions and approaches to handling events happening post-randomisation can change the treatment effect being esti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338740b80454e2daf8bf48a2ae21b87c
https://escholarship.org/uc/item/0p81432n
https://escholarship.org/uc/item/0p81432n
Autor:
Francesca, Conradie, Tatevik R, Bagdasaryan, Sergey, Borisov, Pauline, Howell, Lali, Mikiashvili, Nosipho, Ngubane, Anastasia, Samoilova, Sergey, Skornykova, Elena, Tudor, Ebrahim, Variava, Petr, Yablonskiy, Daniel, Everitt, Genevieve H, Wills, Eugene, Sun, Morounfolu, Olugbosi, Erica, Egizi, Mengchun, Li, Alda, Holsta, Juliano, Timm, Anna, Bateson, Angela M, Crook, Stella M, Fabiane, Robert, Hunt, Timothy D, McHugh, Conor D, Tweed, Salah, Foraida, Carl M, Mendel, Melvin, Spigelman, Adam A, Witney
Background\ud The bedaquiline–pretomanid–linezolid regimen has been reported to have 90% efficacy against highly drug-resistant tuberculosis, but the incidence of adverse events with 1200 mg of linezolid daily has been high. The appropriate dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e75b3743b92e3e20f2adaedefafd0c1
https://openaccess.sgul.ac.uk/id/eprint/114768/1/NEJMoa2119430.pdf
https://openaccess.sgul.ac.uk/id/eprint/114768/1/NEJMoa2119430.pdf
Autor:
Michelle N. Clements, Ian R. White, Andrew J. Copas, Victoria Cornelius, Suzie Cro, David T. Dunn, Matteo Quartagno, Rebecca M. Turner, Conor D. Tweed, A. Sarah Walker
Publikováno v:
NEJM Evid
Effective decision making from randomised controlled clinical trials relies on robust interpretation of the numerical results. However, the language we use to describe clinical trials can cause confusion both in trial design and in comparing results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2f14e9d1352d1ca3d6a430f571696e
https://europepmc.org/articles/PMC7613267/
https://europepmc.org/articles/PMC7613267/