Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Conny Wirtz"'
Publikováno v:
Journal of the American Chemical Society
A nonthermodynamic array of four skipped methylene substituents on the hydrophobic tail renders limaol, a C40-polyketide of marine origin, unique in structural terms. This conspicuous segment was assembled by a two-directional approach and finally co
Publikováno v:
Angewandte Chemie (International Ed. in English)
Of the more than 100 casbane diterpenes known to date, only the eponymous parent hydrocarbon casbene itself has ever been targeted by chemical synthesis. Outlined herein is a conceptually new approach that brings not a single but a variety of casbane
Autor:
Marc Heinrich, Yonghoon Kwon, Alois Fürstner, Conny Wirtz, Saskia Schulthoff, James Y. Hamilton
Publikováno v:
Angewandte Chemie (International Ed. in English)
Total synthesis allowed the constitution of the cytotoxic marine macrolides of the formosalide family to be confirmed and their previously unknown stereostructure to be assigned with confidence. The underlying blueprint was inherently modular to ensu
Publikováno v:
Angewandte Chemie. 130:10872-10877
The assigned structure of the dinoflagellate-derived toxin belizentrin was prepared by total synthesis in form of the corresponding methyl ester for stability reasons. The successful route features an unusual solution for the preparation of a recalci
Publikováno v:
Chemistry - A European Journal. 24:109-114
The first total synthesis of the potent antibiotic disciformycin B (2) is described, which is exceptionally isomerization-prone and transforms into disciformycin A (1) even under notably mild conditions. To outweigh this bias, the approach to 2 hinge
Autor:
Conny Wirtz, Konrad Gebauer, Sebastian Schaubach, Alois Fuerstner, Laura Hoffmeister, Felix Ungeheuer, Marina K. Ilg
Publikováno v:
ChemInform. 47
Autor:
Sebastian Schaubach, Konrad Gebauer, Felix Ungeheuer, Laura Hoffmeister, Marina K. Ilg, Conny Wirtz, Alois Fürstner
Publikováno v:
Chemistry - A European Journal. 22
Publikováno v:
ChemInform. 26
Autor:
Thomas N. Snaddon, Alois Fuerstner, Conny Wirtz, Philipp Buchgraber, Richard Mynott, Richard Goddard
Publikováno v:
ChemInform. 40
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 9(1)
The completion of the first total synthesis of the complex resin glycoside woodrosin I (1) is outlined using the building blocks described in the preceding paper. Key steps involve the TMSOTf-catalyzed coupling of diol 2 with trichloroacetimidate 3 w