Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Conny Kopp-Scheinpflug"'
Autor:
Tamara Radulovic, Ezhilarasan Rajaram, Lena Ebbers, Sara Pagella, Michael Winklhofer, Conny Kopp-Scheinpflug, Hans Gerd Nothwang, Ivan Milenkovic, Anna-Maria Hartmann
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The potassium chloride cotransporter KCC2 is crucial for Cl- extrusion from mature neurons and thus key to hyperpolarizing inhibition. Auditory brainstem circuits contain well-understood inhibitory projections and provide a potent model to s
Externí odkaz:
https://doaj.org/article/851895a1bfaf4993a8ccfd89659a8c02
Publikováno v:
Frontiers in Neural Circuits, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/59f6e2fb32b649f19106fdf52e30cda0
Autor:
Amy Richardson, Victoria Ciampani, Mihai Stancu, Kseniia Bondarenko, Sherylanne Newton, Joern R Steinert, Nadia Pilati, Bruce P Graham, Conny Kopp-Scheinpflug, Ian D Forsythe
Publikováno v:
eLife, Vol 11 (2022)
Kv3 potassium currents mediate rapid repolarisation of action potentials (APs), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploited thi
Externí odkaz:
https://doaj.org/article/7a5ebf62e769488487d88c858f972480
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Sensory systems have to be malleable to context-dependent modulations occurring over different time scales, in order to serve their evolutionary function of informing about the external world while also eliciting survival-promoting behaviors. Stress
Externí odkaz:
https://doaj.org/article/a593ecf1ae644e6eb6e9473a8df3cf0f
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2021)
Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular, reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and cannot be confined, it is highly reactive, so its lifetime is measured in sec
Externí odkaz:
https://doaj.org/article/44de22f0a07d40abaf3f99a568fce089
Autor:
Victoria Ciampani, Nasreen Choudhury, Michelle Anderson, Ian D. Forsythe, Sophie M. Walter, Conny Kopp-Scheinpflug, Susan W. Robinson, Deborah M. Linley, Joern R. Steinert, Vincenzo Marra, Amy Richardson
Publikováno v:
The Journal of Physiology. 598:2199-2222
Kv3.1 and Kv3.3 subunits are highly expressed in the auditory brainstem, with little or no mRNA for Kv3.2 or Kv3.4. Changes in Kv3 currents and action potential (AP) firing were analysed from wild-type, Kv3.1 and Kv3.3 knockout (KO) mice. Both Kv3.1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb33bff9fa052d9af775b565ded1e80
https://doi.org/10.1113/jp279668
https://doi.org/10.1113/jp279668
Autor:
Amy Richardson, Victoria Ciampani, Mihai Stancu, Kseniia Bondarenko, Sherylanne Newton, Joern R Steinert, Nadia Pilati, Bruce P Graham, Conny Kopp-Scheinpflug, Ian D Forsythe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b300739b5db31eee6ad171f121d9e8c5
https://doi.org/10.7554/elife.75219.sa2
https://doi.org/10.7554/elife.75219.sa2
Autor:
Mihai Stancu, Nadia Pilati, Bruce P. Graham, Ian D. Forsythe, Joern R. Steinert, Conny Kopp-Scheinpflug, Amy Richardson, Sherylanne Newton, Victoria Ciampani
SummaryKv3 potassium currents mediate rapid repolarization of action potentials (AP), supporting fast spikes and high repetition rates. Of the four Kv3 gene family members, Kv3.1 and Kv3.3 are highly expressed in the auditory brainstem and we exploit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd16f6335cd8cd6cbebe4343b09fa03
https://doi.org/10.1101/2021.11.02.466934
https://doi.org/10.1101/2021.11.02.466934
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 15 (2021)
Frontiers in Neural Circuits, Vol 15 (2021)
Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular, reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and cannot be confined, it is highly reactive, so its lifetime is measured in sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63917b6f468771db3ba4dc83d1ac660d
https://doi.org/10.3389/fncir.2021.759342
https://doi.org/10.3389/fncir.2021.759342
Autor:
Markus Drexl, Jan M. Deussing, James L. Sinclair, Olga Alexandrova, Conny Kopp-Scheinpflug, Matthew J. Fischl, Margarete A. Ueberfuhr, Sara Pagella
Publikováno v:
The Journal of Physiology
Key points Ongoing, moderate noise exposure does not instantly damage the auditory system but may cause lasting deficits, such as elevated thresholds and accelerated ageing of the auditory system.The neuromodulatory peptide urocortin‐3 (UCN3) is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfc133170fa06ea5c743d7660568c38
http://europepmc.org/articles/PMC6852351
http://europepmc.org/articles/PMC6852351