Výsledky vyhledávání - "Conny H Tran"

Akademický článek

Paroxysmal Discharges in Tissue Slices From Pediatric Epilepsy Surgery Patients: Critical Role of GABAB Receptors in the Generation of Ictal Activity

Autor: Simon Levinson, Conny H. Tran, Joshua Barry, Brett Viker, Michael S. Levine, Harry V. Vinters, Gary W. Mathern, Carlos Cepeda

Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2020)

In the present study, we characterized the effects of bath application of the proconvulsant drug 4-aminopyridine (4-AP) alone or in combination with GABAA and/or GABAB receptor antagonists, in cortical dysplasia (CD type I and CD type IIa/b), tuberou

Externí odkaz: https://doaj.org/article/4b1997950ca44d958256466b41bed4c3

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Abstract WP101: Vessel Wall Enhancement Is Associated With Symptomatic Adult Moyamoya Disease And Syndrome In An American Population

Autor: Conny H Tran, Chahat Rana, William Moore, Ty T Shang

Publikováno v: Stroke. 54

Introduction: Moyamoya Disease (MMD) and Moyamoya Syndrome (MMS) are chronic progressive cerebrovascular disease characterized by bilateral or unilateral stenotic arteries around the circle of Willis with subsequent development of collateral blood ve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::762a20a96c29fad5662ce755a8fc83aa
https://doi.org/10.1161/str.54.suppl_1.wp101

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Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Autor: Conny H. Tran, Johan Nakuci, Michael Vaiana, Kevin M Goff, Ala Somarowthu, Sarah F. Muldoon, Priya Murthy, Ethan M. Goldberg, Nitsan Goldstein

Publikováno v: J Neurosci

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3244cfe9e5c09f7dc7215794a81f93b5
https://doi.org/10.1523/jneurosci.2370-19.2020

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Pathological high frequency oscillations associate with increased GABA synaptic activity in pediatric epilepsy surgery patients

Autor: Harry V. Vinters, Carlos Cepeda, Vannah Wila Yazon, Aria Fallah, Conny H Tran, Joshua Barry, Hiroki Nariai, Simon Levinson, Katerina D. Oikonomou, Gary W. Mathern, Joyce Y. Wu

Publikováno v: Neurobiology of Disease, Vol 134, Iss, Pp-(2020)
Neurobiol Dis

Pathological high-frequency oscillations (HFOs), specifically fast ripples (FRs, >250 Hz), are pathognomonic of an active epileptogenic zone. However, the origin of FRs remains unknown. Here we explored the correlation between FRs recorded with intra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8d75008daac6b0d34c2317d351a62d
http://www.sciencedirect.com/science/article/pii/S0969996119302931

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Cortical Network Dynamics Is Altered in Mouse Models of Huntington's Disease

Autor: Ana María Estrada-Sánchez, Catherine Wang, Conny H Tran, Tim Indersmitten, Peyman Golshani, Carlos Cepeda, Elissa J. Donzis, Michael Levine, Shahrzad Latifi, Katerina D. Oikonomou

Publikováno v: Cereb Cortex

Huntington’s disease (HD) is a neurodegenerative disorder characterized by involuntary movements, cognitive deficits, and psychiatric disturbances. Although evidence indicates that projections from motor cortical areas play a key role in the develo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f739de03431f030bac688237fabdea95
https://pubmed.ncbi.nlm.nih.gov/31761935

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Altered excitatory and inhibitory inputs to striatal medium-sized spiny neurons and cortical pyramidal neurons in the Q175 mouse model of Huntington's disease

Autor: Michael Levine, Tim Indersmitten, Carlos Cepeda, Conny H Tran

Publikováno v: Journal of Neurophysiology. 113:2953-2966

The Q175 knockin mouse model of Huntington's disease (HD) carries a CAG trinucleotide expansion of the human mutant huntingtin allele in its native mouse genomic context and recapitulates the genotype more closely than transgenic models. In this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d8cba9761e31395da55ecb3da89a00
https://doi.org/10.1152/jn.01056.2014

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Partial Amelioration of Peripheral and Central Symptoms of Huntington’s Disease via Modulation of Lipid Metabolism

Autor: Lin Hwang, Carlos Cepeda, Conny H Tran, Michael S. Levine, Michael E. Jung, Kym F. Faull, Gang Deng, Jane Y. Chen

Publikováno v: Journal of Huntington's disease, vol 5, iss 1

Background Huntington's disease (HD) is a fatal, inherited neurodegenerative disorder characterized by uncontrollable dance-like movements, as well as cognitive deficits and mood changes. A feature of HD is a metabolic disturbance that precedes neuro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9b79a79410e63b5d46e21a3ea8a752
https://europepmc.org/articles/PMC5002395/

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In Rasmussen Encephalitis, Hemichannels Associated with Microglial Activation are linked to Cortical Pyramidal Neuron Coupling: A Possible Mechanism for Cellular Hyperexcitability

Autor: Carlos Cepeda, Jane Y. Chen, Michael S. Levine, Harry V. Vinters, My N. Huynh, Gary W. Mathern, Geoffrey C. Owens, Julia W. Chang, Conny H Tran

Publikováno v: Cepeda, C; Chang, JW; Owens, GC; Huynh, MN; Chen, JY; Tran, C; et al.(2014). In Rasmussen Encephalitis, Hemichannels Associated with Microglial Activation are linked to Cortical Pyramidal Neuron Coupling: A Possible Mechanism for Cellular Hyperexcitability. CNS Neuroscience and Therapeutics. doi: 10.1111/cns.12352. UCLA: Retrieved from: http://www.escholarship.org/uc/item/57f1d2fg
CNS neuroscience & therapeutics, vol 21, iss 2
CNS Neuroscience and Therapeutics, vol 21, iss 2
Cepeda, C; Chang, JW; Owens, GC; Huynh, MN; Chen, JY; Tran, C; et al.(2015). In rasmussen encephalitis, hemichannels associated with microglial activation are linked to cortical pyramidal neuron coupling: A possible mechanism for cellular hyperexcitability. CNS Neuroscience and Therapeutics, 21(2), 152-163. doi: 10.1111/cns.12352. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5d90t8q8

© 2014 John Wiley & Sons Ltd. Aims: Rasmussen encephalitis (RE) is a rare but devastating condition, mainly in children, characterized by sustained brain inflammation, atrophy of one cerebral hemisphere, epilepsy, and progressive cognitive deteriora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42843ea5170236302cb507145bdc52f4
http://www.escholarship.org/uc/item/57f1d2fg

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