Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Conny C. Ehren-van Eekelen"'
Autor:
Conny C. Ehren-van Eekelen, B. Eussen, Winand N.M. Dinjens, Jan Trapman, Marcel van der Weiden, Jose J. Knig, Dirk C. J. G. van Alewijk, Lydia D. Van Den Andel-Thijssen, Gert J. van Steenbrugge
Publikováno v:
Genes, Chromosomes and Cancer. 24:119-126
One of the most frequent genetic abnormalities in prostate cancer is loss of the complete or part of the short arm of chromosome 8, indicating the localization of one or more tumor suppressor genes on this chromosomal arm. Using allelotyping, a frequ
Autor:
Robert A. Sikes, Claudia Fasciana, Leland W. K. Chung, Jan Trapman, Conny C. Ehren-van Eekelen, Kitty B.J.M. Cleutjens, Hetty A. G. M. van der Korput
Publikováno v:
Molecular Endocrinology. 11:1256-1265
Prostate-specific antigen (PSA) is a kallikrein-like serine protease, which is almost exclusively synthesized in the luminal epithelial cells of the human prostate. PSA expression is androgen regulated. Previously, we characterized in vitro the proxi
Autor:
Conny C. Ehren-van Eekelen, Jan Trapman, P.W. Faber, Kitty B.J.M. Cleutjens, Hetty A. G. M. van der Korput, Henri C.J. van Rooij
Publikováno v:
Molecular Endocrinology. 11:148-161
Prostate-specific antigen (PSA) is expressed at a high level in the luminal epithelial cells of the prostate and is absent or expressed at very low levels in other tissues. PSA expression can be regulated by androgens. Previously, two functional andr
Autor:
Hetty A. G. M. van der Korput, Albert O. Brinkmann, Kitty B.J.M. Cleutjens, Jan Trapman, Conny C. Ehren-van Eekelen
Publikováno v:
Journal of Biological Chemistry. 271:6379-6388
Transcription of the prostate-specific antigen (PSA) gene is androgen regulated. The PSA promoter contains at position -170 the sequence AGAACAgcaAGTGCT, which is closely related to the ARE (androgen response element) consensus sequence GGTACAnnnTGTT