Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Connor Sharp"'
Autor:
Connor Sharp, Kevin R. Foster
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Humans, and many other species, carry a large set of beneficial microbes. Here, the authors present new theory and data to argue that these vital relationships only work when hosts can control their microbiome and suppress wayward symbionts.
Externí odkaz:
https://doaj.org/article/b1456db332014d09ac37b91dd0d3980e
Publikováno v:
mBio, Vol 13, Iss 2 (2022)
ABSTRACT Bacteria exploit a variety of attack strategies to gain dominance within ecological niches. Prominent among these are contact-dependent inhibition (CDI), type VI secretion (T6SS), and bacteriocins. The cytotoxic endpoint of these systems is
Externí odkaz:
https://doaj.org/article/304a789740cd4ead82ca00ccf351333f
Autor:
Karthik V. Rajasekar, Konrad Zdanowski, Jun Yan, Jonathan T. S. Hopper, Marie-Louise R. Francis, Colin Seepersad, Connor Sharp, Ludovic Pecqueur, Jörn M. Werner, Carol V. Robinson, Shabaz Mohammed, Jennifer R. Potts, Colin Kleanthous
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Counteracting oxidative stress is essential in all organisms. Here, the authors outline a mechanism used by actinomycete bacteria in which oxidation of zinc-binding RsrA blocks its interaction with σR by sequestering hydrophobic residues used to bin
Externí odkaz:
https://doaj.org/article/c89d901e44ac441eb22442e5e5cd39b3
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 7, p e1005652 (2017)
Bacteria exploit an arsenal of antimicrobial peptides and proteins to compete with each other. Three main competition systems have been described: type six secretion systems (T6SS); contact dependent inhibition (CDI); and bacteriocins. Unlike T6SS an
Externí odkaz:
https://doaj.org/article/ec4e218b38564f59a5622222cb9b2113
Autor:
Kevin Foster, Connor Sharp
Humans, and many other species, are host to diverse symbionts. It is often suggested that the mutual benefits of host-microbe relationships can alone explain cooperative evolution. Here, we evaluate this hypothesis with evolutionary modelling. Our mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5aeb41c8d6f612b83883cd5fdbb9c5f
https://doi.org/10.1038/s41467-022-30971-8
https://doi.org/10.1038/s41467-022-30971-8
Autor:
Nicholas G. Housden, Connor Sharp, Daniel Walker, Khedidja Mosbahi, Renata Kaminska, Iva Atanaskovic, Colin Kleanthous
Publikováno v:
Journal of Molecular Biology
Pseudomonas aeruginosa is a priority pathogen for the development of new antibiotics, particularly because multi-drug-resistant strains of this bacterium cause serious nosocomial infections and are the leading cause of death in cystic fibrosis patien
Bacteria exploit a variety of attack strategies to gain dominance within ecological niches. Prominent amongst these are contact-dependent inhibition (CDI), type VI secretion (T6SS) and bacteriocins. The cytotoxic endpoint of these systems is often th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75a591676118ea56cdf608c6f0c74b70
https://doi.org/10.1101/2021.11.17.469063
https://doi.org/10.1101/2021.11.17.469063
Autor:
Connor Sharp, Bruno S. Lopes, Thi Kim Loan Nguyen, Shi-Qi An, James P. R. Connolly, Clare L. Kirkpatrick
Publikováno v:
An, S-Q, Lopes, B S, Connolly, J P R, Sharp, C, Nguyen, T K L & Kirkpatrick, C L 2021, ' Going virtual : a report from the sixth Young Microbiologists Symposium on 'Microbe Signalling, Organisation and Pathogenesis' ', Microbiology, vol. 167, no. 3, 001024 . https://doi.org/10.1099/mic.0.001024
Microbiology
Microbiology
The sixth Young Microbiologists Symposium on 'Microbe Signalling, Organisation and Pathogenesis' was scheduled to be held at the University of Southampton, UK, in late August 2020. However, due to the health and safety guidelines and travel restricti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899c5b8b4631f9ec7ca1629e0f4ca52b
https://findresearcher.sdu.dk:8443/ws/files/181452077/micro001024.pdf
https://findresearcher.sdu.dk:8443/ws/files/181452077/micro001024.pdf
Autor:
Nicholas G, Housden, Patrice, Rassam, Sejeong, Lee, Firdaus, Samsudin, Renata, Kaminska, Connor, Sharp, Jonathan D, Goult, Marie-Louise, Francis, Syma, Khalid, Hagan, Bayley, Colin, Kleanthous
Publikováno v:
Biochemistry
Protein bacteriocins are potent narrow spectrum antibiotics that exploit outer membrane porins to kill bacteria by poorly understood mechanisms. Here, we determine how colicins, bacteriocins specific for Escherichia coli, engage the trimeric porin Om
Autor:
Nicholas G. Housden, Patrice Rassam, Sejeong Lee, Firdaus Samsudin, Renata Kaminska, Connor Sharp, Jonathan D. Goult, Marie-Louise Francis, Syma Khalid, Hagan Bayley, Colin Kleanthous
Publikováno v:
Biochemistry
Protein bacteriocins are potent narrow spectrum antibiotics that exploit outer membrane porins to kill bacteria by poorly understood mechanisms. Here, we determine how colicins, bacteriocins specific for Escherichia coli, engage the trimeric porin Om