Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Connor P. Hayes"'
Autor:
Nihat B. Agaoglu, Busra Unal, Connor P. Hayes, McKenzie Walker, Ozden Hatirnaz Ng, Levent Doganay, Nisan D. Can, Huma Q. Rana, Arezou A. Ghazani
Publikováno v:
Cancer Medicine, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objective Turkish genome is underrepresented in large genomic databases. This study aims to evaluate the effect of allele frequency in the Turkish population in determining the clinical utility of germline findings in breast cancer, includin
Externí odkaz:
https://doaj.org/article/0e8c822e43624d2f9734ff8febc97f18
Autor:
Raymond A. Isidro, Anu Chittenden, McKenzie Walker, Alison Schwartz, Diane R. Koeller, Connor P. Hayes, Busra Unal, Monica Devi Manam, Ryan M. Buehler, Danielle K. Manning, Lynette M. Sholl, Mark S. Redston, Matthew B. Yurgelun, Huma Q. Rana, Judy E. Garber, Arezou A. Ghazani
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
The presence of variants of uncertain significance (VUS) in DNA mismatch repair (MMR) genes leads to uncertainty in the clinical management of patients being evaluated for Lynch syndrome (LS). Currently, there is no platform to systematically use tum
Externí odkaz:
https://doaj.org/article/6d8a9b32038a4cdca4bc04f27dba67f4
Autor:
Alison Schwartz, Danielle K. Manning, Diane R. Koeller, Anu Chittenden, Raymond A. Isidro, Connor P. Hayes, Feruza Abraamyan, Monica Devi Manam, Meaghan Dwan, Justine A. Barletta, Lynette M. Sholl, Matthew B. Yurgelun, Huma Q. Rana, Judy E. Garber, Arezou A. Ghazani
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Genomic profiles of tumors are often unique and represent characteristic mutational signatures defined by DNA damage or DNA repair response processes. The tumor-derived somatic information has been widely used in therapeutic applications, but it is g
Externí odkaz:
https://doaj.org/article/16388d6d31534f26bcb25927bd33d184
Autor:
Diane R. Koeller, Danielle K. Manning, Alison Schwartz, Anu Chittenden, Connor P. Hayes, Feruza Abraamyan, Huma Q. Rana, Neal I. Lindeman, Judy E. Garber, Arezou A. Ghazani
Publikováno v:
MethodsX, Vol 9, Iss , Pp 101761- (2022)
The interpretation of hereditary genetic sequencing variants is often limited due to the absence of functional data and other key evidence to assess the role of variants in disease. Cancer genetics is unique, as two sets of genomic information are of
Externí odkaz:
https://doaj.org/article/87e8e139773c4bc2a908d6f6e6aedd90