Evaluation of waning of IgG antibody responses after rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccines: a modelling study from the PREVAC randomized trial.

Autor: Valayer S; Infection, Antimicrobials, Modelling, Evolution (IAME), Université Sorbonne Paris Nord, Université Sorbonne Paris Cité, and Institut national de la santé et de la recherche médicale (Inserm), Paris, France.; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France., Alexandre M; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France.; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France., Prague M; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France.; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France., Beavogui AH; Centre National de Formation et de Recherche en Santé Rurale (CNFRSR) de Mafèrinyah, Ministère de la Santé et de l'Hygiène Publique, Mafèrinyah, Guinea., Doumbia S; University Clinical Research Center, University of Sciences, Technique and Technology of Bamako, Bamako, Mali., Kieh M; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia., Greenwood B; London School of Hygiene & Tropical Medicine (LSHTM), London, UK., Leigh B; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone., Poupelin M; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France., Schwimmer C; European Clinical Trials Platform & Development (EUCLID), Université de Bordeaux, Centre Hospitalier Universitaire Bordeaux, and Inserm, ISPED, Bordeaux, France., Sow SO; Centre pour le Développement des Vaccins, Ministère de la Santé et du Développement Social du Mali, Bamako, Mali., Berry IM; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Frederick, MD, USA., Kuhn JH; Integrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Frederick, MD, USA., Fusco D; French Agency for Research on AIDS and Viral Hepatitis (ANRS), Emerging Infectious Diseases, PariSanté Campus, Paris, France.; Department of Infectious Diseases Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany., Cauwelaert ND; Inserm, Paris Cedex 13, France., Watson-Jones D; London School of Hygiene & Tropical Medicine (LSHTM), London, UK., Thiébaut R; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France.; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France.; European Clinical Trials Platform & Development (EUCLID), Université de Bordeaux, Centre Hospitalier Universitaire Bordeaux, and Inserm, ISPED, Bordeaux, France.; Pôle de Santé Publique, Centre Hospitalier Universitaire Bordeaux, Bordeaux, France., Lévy Y; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France.; Inserm, Paris Cedex 13, France.; Service d'Immunologie Clinique et Maladies Infectieuses, Hôpital Henri-Mondor, Créteil, France., Yazdanpanah Y; Infection, Antimicrobials, Modelling, Evolution (IAME), Université Sorbonne Paris Nord, Université Sorbonne Paris Cité, and Institut national de la santé et de la recherche médicale (Inserm), Paris, France.; Inserm, Paris Cedex 13, France.; Service de Maladies Infectieuses et Tropicales, Hôpital Bichat, Paris, France., Richert L; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France.; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France.; European Clinical Trials Platform & Development (EUCLID), Université de Bordeaux, Centre Hospitalier Universitaire Bordeaux, and Inserm, ISPED, Bordeaux, France.; Pôle de Santé Publique, Centre Hospitalier Universitaire Bordeaux, Bordeaux, France., Lhomme E; Bordeaux Population Health Research Centre, Université de Bordeaux, Inserm, and Inria, Bordeaux, France.; Vaccine Research Institute, Faculté de Médicine, Université Paris-Est Créteil, Créteil, France.; European Clinical Trials Platform & Development (EUCLID), Université de Bordeaux, Centre Hospitalier Universitaire Bordeaux, and Inserm, ISPED, Bordeaux, France.; Pôle de Santé Publique, Centre Hospitalier Universitaire Bordeaux, Bordeaux, France., Aboulhab J; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Aguirre-MacKenzie M BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Akoo P MB, ChB; London School of Hygiene & Tropical Medicine, London, UK, Akpa E MSN, MPH, RN; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Akpata R; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Albert S BA, MPH; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Ale BM MD, MSc, MPH; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Alimamy-Bangura S MB, ChB; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Andong P MSt; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Andrews BC; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Anoma S; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Atri N MPH, CPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Augier A MCom; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Awuondo K MSc; London School of Hygiene & Tropical Medicine, London, UK, Ayouba A; Recherche Translationnelle Appliquée au VIH et aux Maladies Infectieuses, Institut de Recherche pour le Développement, University of Montpellier, INSERM, 34090, Montpellier, France, Badio M MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Bagayoko A; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Balde A MPH; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Balssa J PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, Bangura LM BSc; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Barrington K MPA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Barte de Saint Fare E BA; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Baseler B MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Bauder A BA, PMP; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Bauduin C MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Bawo L MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Beavogui AH MD, PhD; Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Maferinyah, Guinea, Belson M BS; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Ben-Farhat S MEng; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Bererd M BS; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Bernaud N MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Beyslow T PharmD; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Biai N MSc; Recherche Translationnelle Appliquée au VIH et aux Maladies Infectieuses, Institut de Recherche pour le Développement, University of Montpellier, INSERM, 34090, Montpellier, France, Billioux J; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Billouin-Frazier S MSc; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Binachon B MD, MPH; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Blie J MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Bockstal V; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Boison P MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Bolay F; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Boly A MM; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Bonawitz RE MD, MS; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Borg AG MCM; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Bosompem S PharmD, MSc; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Bozman C MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Brady T MPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Browne S RN, BSN; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Bullis R; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Cagniard B; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Cahill K RN, MSc, CCRC, RAC; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Cai Y; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Camara AA MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Camara AK; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Camara AM; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Campagne A; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Campion C MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Cantan A BSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France; Univ. Bordeaux, INSERM, MART, UMS 54, F-33000, Bordeaux, France, Cash J BS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Chai SP BBio-MedSc; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Chambelin F MHist; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Chea M BSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Chêne G MD, PhD; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Choi E; London School of Hygiene & Tropical Medicine, London, UK, Chouinard M MSW; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Chung F; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Chung L PharmD; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Ciancia S MJ; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Cisse PN; Département de Sociologie, FLSH, Université Cheikh Anta DIOP, Dakar, Sénégal, Cline-Cole E MA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Colin C MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Coller BA; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Conde DS; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Cone K, Cone K MSW, LCSW-C, C-SWHC; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Connor L MS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Connor N MSc; London School of Hygiene & Tropical Medicine, London, UK, Cooper JB MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Couffin-Cardiergues S; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Coulibaly F BS; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Coulibaly M PharmD, MSc; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Crew P PharmD, MPH, BCPS; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Dabakuyo-Yonli S PharmD, PhD; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Dabitao D PharmD, PhD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Damerval T; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Davis B MPH; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Deen GF MD, MSc; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Dekeyster E; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Delfraissy JF MD, PhD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Delmas C MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Diakite M PharmD, DPhil; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Diallo A MD, MPH; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, Diallo FA; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Diallo MS MD, MPH; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Diarra A MSc; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Diarra S MSc, PhD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Diawara O BS; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali, Dighero-Kemp B BSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Diop S MSc, PhD; Liberia Institute for Biomedical Research Ethics Committee/National, Monrovia, Liberia, Diouf W; Département de Sociologie, FLSH, Université Cheikh Anta DIOP, Dakar, Sénégal, Dixit S; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Djenabou B MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Doepel L BA; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, D’Ortenzio E MD, MPH; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France; AP-HP, Hôpital Bichat-Claude Bernard, Service de Maladies Infectieuses et Tropicales, Paris, F-75018, France, Doumbia S MD, PhD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Doumbia MM; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali, Douoguih M MD, MPH; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Dozier N MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Cauwelaert ND; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, DuChêne A BS; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Duvenhage M NDIPIT; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Eckes R RN; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Elliott E MSc; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Enria L; London School of Hygiene & Tropical Medicine, London, UK, Espérou H; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Etienne C MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Eyler A HSD; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Fakoli L MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Fallah M; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Fauvel MA MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Faye S; Département de Sociologie, FLSH, Université Cheikh Anta DIOP, Dakar, Sénégal, Fayiah J MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Fleck S; London School of Hygiene & Tropical Medicine, London, UK, Fofana V BComp; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Tchos KF MD, MPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Franklin K MPhil, MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Fusco D; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Gaddah A; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Gaignet M MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Gallagher K; London School of Hygiene & Tropical Medicine, London, UK, Gardner J BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Gichini H MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Gozalbes JG; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Grandits G MS; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Gray M BPharm; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Greenwood B; London School of Hygiene & Tropical Medicine, London, UK, Grobler N; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Gross R MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Grue L RN, BS, BSN; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Grund B; School of Statistics, University of Minnesota, Minneapolis, MN, USA, Guindo O MSc, PharmD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Gupta S DrPH, MPH; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Haidara F; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali, Hamz B PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Hancox E MSc; London School of Hygiene & Tropical Medicine, London, UK, Hébert JC MSL; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Hendriks J; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Hensley P MPh; London School of Hygiene & Tropical Medicine, London, UK, Hensley LE PhD, MSPH; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Herpin B MSN; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Higgs E MD, DTMH, MIA; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Hilton T BPharm, MSc; London School of Hygiene & Tropical Medicine, London, UK, Hneino M; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Höeltermann TA BSc, MPH; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Holley HP; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Hoover M; Advanced BioMedical Laboratories, L.L.C., 1605 Industrial Hwy, Cinnaminson, NJ, USA, Howard N; London School of Hygiene & Tropical Medicine, London, UK, Hughes M BA, MBA, CPM, PMP; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Ilo D MD, MPH; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Irvine S BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Ishola D MD, PhD; London School of Hygiene & Tropical Medicine, London, UK, Jato Y MPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Joe M MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Johnson M MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Kaba AS; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Kagan J; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Kallon K MSc; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Kamara M MBChB, MSc; London School of Hygiene & Tropical Medicine, London, UK, Kante M BS; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Katoudi J MD, MPH; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Keita CM; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Keita S; Agence Nationale de Sécurité Sanitaire, Conakry, Guinea, Keita S; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Kennedy SB MD, MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Keshinro B MBBS, FWACP; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Kiawu H MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Kieh M MD, MSMHC; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Killinger B BA; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Kinda M MD, MBA; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Kirchoff M PharmD, MSc, MBA; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Kocher G MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Kodio M PharmD; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali, Kohn B BSc; London School of Hygiene & Tropical Medicine, London, UK, Koivogui L PharmD, PhD; INSP (Institut Nationale de Santé Publique), Conakry, Guinea, Kojan R; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Koli CF é, PharmD; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Koli JS é, MD; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Kollie D BSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Kopka S MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Koroma B BPharm; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Kowuor D BSc, MSc, PhD; London School of Hygiene & Tropical Medicine, London, UK, Kpayieli-Freeman C MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Kwast L MSc; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Lacabaratz C; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; Vaccine Research Institute, Univ. Paris Est Créteil, Henri Mondor Hospital, Créteil, France, Lacarra B; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Lambert L BS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Lambeth C BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Lancrey-javal S PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, Lane HC; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Langba S BSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Lawal B MSc; London School of Hygiene & Tropical Medicine, London, UK, Lee AW; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Lee S; London School of Hygiene & Tropical Medicine, London, UK, Lees S; London School of Hygiene & Tropical Medicine, London, UK, Lefevre A; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Leigh B MD, MSc; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Lemarcis F; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Lévy Y MD, PhD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; Vaccine Research Institute, Univ. Paris Est Créteil, Henri Mondor Hospital, Créteil, France, Levy-Marchal C; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Leyssen M MD, PhD; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Lhomme E MD, PhD; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform and U1219 BPH Inria Sistm, F-33000, Bordeaux, France, Liang J MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Linga M MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Liu K; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Lowe B MPhil; London School of Hygiene & Tropical Medicine, London, UK, Lysander J MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Mahamadou I PharmD; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Maljkovic-Berry I; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Mambiah M ASc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Manno D MD, PhD; London School of Hygiene & Tropical Medicine, London, UK, Marchand J MS; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Marron L MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Massaquoi MB MD, MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Masson L MIBL; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Matard C BS; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Mazur S BS; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, McCullough J BS; Advanced BioMedical Laboratories, L.L.C., 1605 Industrial Hwy, Cinnaminson, NJ, USA, McFadyen K MPH; Janssen Vaccines and Prevention BV Leiden, The Netherlands, McLean C; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Mercier N PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Michavila P BBus; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Miller T RN, BSN; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Millimouno NP; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Miranda A MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Mohamed S BJ; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Mooney T BA; London School of Hygiene & Tropical Medicine, London, UK, Muamba D; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Mulbah J BPharm; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Ndamenyaa RL MD, MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Neaton J; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Neboua D; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Nelson M BSN, MS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Newell K MPH, MEd; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Nguyen VK; École de santé publique de l'Université de Montréal, Montréal, Canada, Njie Y BSc; London School of Hygiene & Tropical Medicine, London, UK, Njoh W MSN; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Novotney-Barry A MSC; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Onorato M BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Onwuchekwa U BSc; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Orsega S MSN, FNP-BC; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Ortega-Perez I PhD, MPH; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, Osborne C BS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Otieno T MSC; London School of Hygiene & Tropical Medicine, London, UK, Oulaï D MS, PMP; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Patel S BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Peart D; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Peeters M MSc; Recherche Translationnelle Appliquée au VIH et aux Maladies Infectieuses, Institut de Recherche pour le Développement, University of Montpellier, INSERM, 34090, Montpellier, France, Pettitt J MD, PhD; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Peiffer-Smadja N MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Phillips R; London School of Hygiene & Tropical Medicine, London, UK, Pierson J; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Piot P MD, PhD; London School of Hygiene & Tropical Medicine, London, UK, Piziali M JD, MSc; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Pong S PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France, Postnikova E; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Proffitt C MA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Quach A; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Quigley S MSSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Randunu N BSc, MBA; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Richert L MD, PhD; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform and U1219 BPH Inria Sistm, F-33000, Bordeaux, France, Rivière P MSc; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Robinson C; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Roy C; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France; Univ. Bordeaux, INSERM, MART, UMS 54, F-33000, Bordeaux, France, Russell AF MS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Sahr P; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Saliba K MSc, PhD; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Samai M MBBS, PhD; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Samake S PharmD, MSc; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Sandrus J AA; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Sanogo I MsP, MD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Sarro YS PharmD, PhD; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Sawadogo S MD, MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Sayadi S MD, MPH; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Schvartz M; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Schwimmer C; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Secka F BSc, MSc, MBChB; London School of Hygiene & Tropical Medicine, London, UK, Sharma H MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Shelley D MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Shobayo B MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Siddiqui S MD, MPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Simon J; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Simpson S MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Sivahera BM; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Slater K; London School of Hygiene & Tropical Medicine, London, UK, Smolskis M BSN, MA; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Smout E MD, MSc; London School of Hygiene & Tropical Medicine, London, UK, Snowden E MA; London School of Hygiene & Tropical Medicine, London, UK, Soutthiphong AA MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France; Univ. Bordeaux, INSERM, MART, UMS 54, F-33000, Bordeaux, France, Sow A MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Sow SO MD, MSc; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Sow Y MD, MPH; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Stirratt M; National Institute of Mental Health, Bethesda, MD, USA, Stoop J; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Subramaniam G MSc; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Surugue L MJ; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Swales N MSc; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Tamba S RN, BSN; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Tang C BSc; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Tangara C MSc; University Clinical Research Center (UCRC), University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali, Tapia MD; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 West Baltimore Street Baltimore, MD, 21201-1509, USA, Teahton J MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Tegli J MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Termote M MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Thaurignac G MSC; Recherche Translationnelle Appliquée au VIH et aux Maladies Infectieuses, Institut de Recherche pour le Développement, University of Montpellier, INSERM, 34090, Montpellier, France, Thiebaut R MD, PhD; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Thompson G BS; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Tierney J BSN, MPM; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Tindanbil D MSc; London School of Hygiene & Tropical Medicine, London, UK, Tour A é, PharmD, MPH, PhD; INSP (Institut Nationale de Santé Publique), Conakry, Guinea, Towalid E BPharm; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Traina S BS; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Traore A PharmD; Centre pour le Développement des Vaccins, Ministère de la Santé, Bamako, Mali, Tyee T PharmD; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Vallée D PharmD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Vatrinet R; French Institute for Health and Medical Research (Inserm), 75013, Paris, France, Vincent C MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Vogel S RN, BSN; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Wallet C MSc; Univ. Bordeaux, INSERM, Institut Bergonié, CHU de Bordeaux, CIC-EC 1401, Euclid/F-CRIN clinical trials platform, F-33000, Bordeaux, France, Warren T; National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA, Watson-Jones D MD, PhD; London School of Hygiene & Tropical Medicine, London, UK, Weaver W MSc; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Wentworth D MPH; School of Public Health, University of Minnesota, Minneapolis, MN, USA, Wesseh C BSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Whitworth H; London School of Hygiene & Tropical Medicine, London, UK, Whitworth J; London School of Hygiene & Tropical Medicine, London, UK, Wiedemann A; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; Vaccine Research Institute, Univ. Paris Est Créteil, Henri Mondor Hospital, Créteil, France, Willems W; Janssen Vaccines and Prevention BV Leiden, The Netherlands, Wilson B MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Wolf J; Merck Sharp & Dohme Corp, Inc., Kenilworth, NJ, USA, Wurie A MD, MSc; College of Medicine and Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown, Sierra Leone, Yamadjako D MS; Leidos Biomedical Research, Inc., Frederick, MD, 21704, USA, Yaradouno M MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Yarmie Q MSc; Partnership for Research on Ebola Virus in Liberia (PREVAIL), Monrovia, Liberia, Yazdanpanah Y MD, PhD; French Institute for Health and Medical Research (Inserm), 75013, Paris, France; ANRS Emerging Infectious Diseases, Paris, France; AP-HP, Hôpital Bichat-Claude Bernard, Service de Maladies Infectieuses et Tropicales, Paris, F-75018, France, Yu S BS; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA, Zeggani Z MSc; The Alliance for International Medical Action, Alima, B.P.15530, Dakar, Sénégal, Zhou H BS; Integrated Research Facility at Fort Detrick (IRF-Frederick), National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Fort Detrick, Frederick, MD, USA

Publikováno v: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2432353. Date of Electronic Publication: 2024 Dec 09.