Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Connor J. Liu"'
Autor:
Tanner M. Johanns, Christopher A. Miller, Connor J. Liu, Richard J. Perrin, Diane Bender, Dale K. Kobayashi, Jian L. Campian, Michael R. Chicoine, Ralph G. Dacey, Jiayi Huang, Edward F. Fritsch, William E. Gillanders, Maxim N. Artyomov, Elaine R. Mardis, Robert D. Schreiber, Gavin P. Dunn
Publikováno v:
OncoImmunology, Vol 8, Iss 4 (2019)
Neoantigens represent promising targets for personalized cancer vaccine strategies. However, the feasibility of this approach in lower mutational burden tumors like glioblastoma (GBM) remains unknown. We have previously reported the use of an immunog
Externí odkaz:
https://doaj.org/article/8dde9e453942466c919f33fd089ee9d6
Autor:
David M Kranz, Michael J White, Mao Li, Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Diane E Bender, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background Adoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
Externí odkaz:
https://doaj.org/article/67ba15afade74b8a9caa7534c5ef5ce0
Autor:
Jay A. Bowman-Kirigin, Rupen Desai, Brian T. Saunders, Anthony Z. Wang, Maximilian O. Schaettler, Connor J. Liu, Alexandra J. Livingstone, Dale K. Kobayashi, Vivek Durai, Nicole M. Kretzer, Gregory J. Zipfel, Eric C. Leuthardt, Joshua W. Osbun, Michael R. Chicoine, Albert H. Kim, Kenneth M. Murphy, Tanner M. Johanns, Bernd H. Zinselmeyer, Gavin P. Dunn
Publikováno v:
Cancer Immunology Research. 11:20-37
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
Supplementary Figures and Tables.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ee81d152485914d2570e049914be76
https://doi.org/10.1158/2326-6066.22546134.v1
https://doi.org/10.1158/2326-6066.22546134.v1
Autor:
Gavin P. Dunn, Bernd H. Zinselmeyer, Tanner M. Johanns, Kenneth M. Murphy, Albert H. Kim, Michael R. Chicoine, Joshua W. Osbun, Eric C. Leuthardt, Gregory J. Zipfel, Nicole M. Kretzer, Vivek Durai, Dale K. Kobayashi, Alexandra J. Livingstone, Connor J. Liu, Maximilian O. Schaettler, Anthony Z. Wang, Brian T. Saunders, Rupen Desai, Jay A. Bowman-Kirigin
The central nervous system (CNS) antigen-presenting cell (APC) that primes antitumor CD8+ T-cell responses remains undefined. Elsewhere in the body, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain parenchyma c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb45f311006488389e8bbe0e0d51222
https://doi.org/10.1158/2326-6066.c.6551106
https://doi.org/10.1158/2326-6066.c.6551106
Autor:
Maximilian O Schaettler, Rupen Desai, Anthony Z Wang, Alexandra J Livingstone, Dale K Kobayashi, Andrew T Coxon, Jay A Bowman-Kirigin, Connor J Liu, Mao Li, Diane E Bender, Michael J White, David M Kranz, Tanner M Johanns, Gavin P Dunn
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e006121
BackgroundAdoptive cellular therapies with chimeric antigen receptor T cells have revolutionized the treatment of some malignancies but have shown limited efficacy in solid tumors such as glioblastoma and face a scarcity of safe therapeutic targets.
The use of novel immunotherapeutic agents in treating malignant brain tumors faces considerable challenges. Cancer immunogenomics represents a genomic framework for studying the dynamic interactions between the host immune system and tumor microenvir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30fa4df044cd25fd6c001a7780c629f9
https://doi.org/10.1016/b978-0-12-819755-4.00014-x
https://doi.org/10.1016/b978-0-12-819755-4.00014-x
Autor:
April Bell, Orin Bloch, Lakshmi Bollu, E. Antonio Chiocca, Pavlina Chuntova, Andrew T. Coxon, Gavin P. Dunn, Susannah G. Ellsworth, Peter E. Fecci, Ryan Gilbert, Stuart A. Grossman, Aden P. Haskell-Mendoza, Lan B. Hoang-Minh, Michael Jin, Miri Kim, Erik Ladomersky, Kristen L. Lauing, Gordon Li, Connor J. Liu, Selena Lorrey, Duane A. Mitchell, Hideho Okada, Jessica Waibl Polania, Erik Rabin, Isaac H. Solomon, Derek A. Wainwright, Payal B. Watchmaker, Daniel Wilkinson, Adela Wu, Lijie Zhai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40baf11ebae8382ccad6c2e04695fe93
https://doi.org/10.1016/b978-0-12-819755-4.09987-2
https://doi.org/10.1016/b978-0-12-819755-4.09987-2
Autor:
Tanner M. Johanns, Dale K. Kobayashi, Eric C. Leuthardt, Albert H. Kim, Brian Saunders, Gavin P. Dunn, Joshua W. Osbun, Gregory J. Zipfel, Rupen Desai, Alexandra J. Livingstone, Vivek Durai, Max Schaettler, Connor J. Liu, Nicole M. Kretzer, Bernd H. Zinselmeyer, Michael R. Chicoine, Kenneth M. Murphy, Jay A. Bowman-Kirigin, Anthony Z. Wang
The central nervous system (CNS) antigen presenting cell (APC) which primes anti-tumor CD8+ T cell responses remains undefined. Elsewhere, the conventional dendritic cell 1 (cDC1) performs this role. However, steady-state brain cDC1 are rare; cDC loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cb8256bd397b7d60fca7c7827161430
https://doi.org/10.1101/2021.09.13.460088
https://doi.org/10.1101/2021.09.13.460088
Autor:
Malachi Griffith, Susanna Kiwala, Ramaswamy Govindan, William C. Chapman, S. Joshua Swamidass, Connor J. Liu, Ravindra Uppaluri, Jasreet Hundal, Yang-Yang Feng, Elaine R. Mardis, Obi L. Griffith
Publikováno v:
Nature genetics
Recent efforts to design personalized cancer immunotherapies use predicted neoantigens, but most neoantigen prediction strategies do not consider proximal (nearby) variants that alter the peptide sequence and may influence neoantigen binding. We eval