Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Connor J. Dwyer"'
Autor:
Alhaji H. Janneh, Mohamed Faisal Kassir, Connor J. Dwyer, Paramita Chakraborty, Jason S. Pierce, Patrick A. Flume, Hong Li, Satish N. Nadig, Shikhar Mehrotra, Besim Ogretmen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract COVID-19 pandemic exerts a health care emergency around the world. The illness severity is heterogeneous. It is mostly unknown why some individuals who are positive for SARS-CoV-2 antibodies stay asymptomatic while others show moderate to se
Externí odkaz:
https://doaj.org/article/305a4cbf085d4c1e8de8df3259f7cba4
Autor:
Connor J. Dwyer, Colleen A. Cloud, Cindy Wang, Philip Heidt, Paramita Chakraborty, Tara F. Duke, Shannon McGue, Braxton Jeffcoat, Jaclyn Dunne, Logan Johnson, Seungho Choi, Georges J. Nahhas, Amy S. Gandy, Nikolina Babic, Frederick S. Nolte, Philip Howe, Besim Ogretmen, Vamsi K. Gangaraju, Stephen Tomlinson, Brian Madden, Tracy Bridges, Patrick A. Flume, John Wrangle, Mark P. Rubinstein, Prabhakar K. Baliga, Satish N. Nadig, Shikhar Mehrotra
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102489- (2021)
Summary: The SARS-CoV-2 viral pandemic has induced a global health crisis, which requires more in-depth investigation into immunological responses to develop effective treatments and vaccines. To understand protective immunity against COVID-19, we sc
Externí odkaz:
https://doaj.org/article/81d3dd2c458348b2ad48c0ed81cf4392
Autor:
Guillermo O. Rangel Rivera, Hannah M. Knochelmann, Connor J. Dwyer, Aubrey S. Smith, Megan M. Wyatt, Amalia M. Rivera-Reyes, Jessica E. Thaxton, Chrystal M. Paulos
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Emerging reports show that metabolic pathways can be targeted to enhance T cell-mediated immunity to tumors. Yet, tumors consume key metabolites in the host to survive, thus robbing T cells of these nutrients to function and thrive. T cells are often
Externí odkaz:
https://doaj.org/article/b97a96fc05df4b82bb16cd5baaca35a4
Autor:
Connor J. Dwyer, Hannah M. Knochelmann, Aubrey S. Smith, Megan M. Wyatt, Guillermo O. Rangel Rivera, Dimitrios C. Arhontoulis, Eric Bartee, Zihai Li, Mark P. Rubinstein, Chrystal M. Paulos
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Adoptive T cell transfer therapy (ACT) using tumor infiltrating lymphocytes or lymphocytes redirected with antigen receptors (CAR or TCR) has revolutionized the field of cancer immunotherapy. Although CAR T cell therapy mediates robust responses in p
Externí odkaz:
https://doaj.org/article/825995c99c0a4d7983aee31e01cf63b3
Autor:
Hannah M. Knochelmann, Aubrey S. Smith, Connor J. Dwyer, Megan M. Wyatt, Shikhar Mehrotra, Chrystal M. Paulos
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Genetic redirection of T lymphocytes with chimeric antigen receptors (CARs) has soared from treating cancers preclinically to FDA approval for hematologic malignancies and commercial-grade production scale in under 30 years. To date, solid tumors are
Externí odkaz:
https://doaj.org/article/229323c4814e4454ae5f589352312db2
252 The combination of ACT and INDUKINE therapy leads to improved antitumor immunity in solid tumors
Autor:
Kyriakos Economides, Kristin Morris, Andres Salmeron, Connor J Dwyer, Heather R Brodkin, Daniel J Hicklin, Cynthia Seidel-Dugan, William M Winston, Olivia G Donovan, Julie LePrevost
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2f1f22f5f1b0489b8bac8a7f7313a641
Autor:
Christopher J. Nirschl, Heather R. Brodkin, Celesztina Domonkos, Connor J. Dwyer, Daniel J. Hicklin, Nesreen Ismail, Cynthia Seidel-Dugan, Philipp Steiner, Zoe Steuert, Jenna M. Sullivan, William M. Winston, Andres Salmeron
Publikováno v:
Cancer Immunology Research. :OF1-OF16
IL-12 is a pleotropic inflammatory cytokine, which has broad stimulatory effects on various immune cell populations, making it an attractive target for cancer immunotherapy. However, despite generating robust antitumor activity in syngeneic murine tu
Autor:
Andres Salmeron, William M. Winston, Jenna M. Sullivan, Zoe Steuert, Philipp Steiner, Cynthia Seidel-Dugan, Nesreen Ismail, Daniel J. Hicklin, Connor J. Dwyer, Celesztina Domonkos, Heather R. Brodkin, Christopher J. Nirschl
Differential Gene Expression Analysis of EMT-6 Tumor Infiltrating CD8+ T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2464da6670affb9c7e905d279347ce73
https://doi.org/10.1158/2326-6066.22930490
https://doi.org/10.1158/2326-6066.22930490
Autor:
Andres Salmeron, William M. Winston, Jenna M. Sullivan, Zoe Steuert, Philipp Steiner, Cynthia Seidel-Dugan, Nesreen Ismail, Daniel J. Hicklin, Connor J. Dwyer, Celesztina Domonkos, Heather R. Brodkin, Christopher J. Nirschl
Gene Ontology Analysis of RNA from MC38 Tumors Following mWTX-330 Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c2bac2d03d297574ef3b9484c0c934
https://doi.org/10.1158/2326-6066.22930496
https://doi.org/10.1158/2326-6066.22930496
Autor:
Andres Salmeron, William M. Winston, Jenna M. Sullivan, Zoe Steuert, Philipp Steiner, Cynthia Seidel-Dugan, Nesreen Ismail, Daniel J. Hicklin, Connor J. Dwyer, Celesztina Domonkos, Heather R. Brodkin, Christopher J. Nirschl
Supplemental Figures 1-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649831fe0fa3ceea6306bc7112709245
https://doi.org/10.1158/2326-6066.22930499
https://doi.org/10.1158/2326-6066.22930499