Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Connor G. G. Bamford"'
Autor:
Lindsay Broadbent, Connor G. G. Bamford, Guillermo Lopez Campos, Sheerien Manzoor, David Courtney, Ahlam Ali, Olivier Touzelet, Conall McCaughey, Ken Mills, Ultan F. Power
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease-19 (COVID-19) pandemic, was identified in late 2019 and caused >5 million deaths by February 2022. To date, targeted antiviral interventions against CO
Externí odkaz:
https://doaj.org/article/4820500485534bfd92cf98d195b99d42
Autor:
Stephen H. Bell, Derek J. Fairley, Hannele Kettunen, Juhani Vuorenmaa, Juha Orte, Connor G. G. Bamford, John W. McGrath
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Chemical methods of virus inactivation are used routinely to prevent viral transmission in both a personal hygiene capacity but also in at-risk environments like hospitals. Several virucidal products exist, including hand soaps, gels, and su
Externí odkaz:
https://doaj.org/article/aae110d45368444c8acbc3b201a8dab9
Autor:
Cuncai Guo, Dorothee Reuss, Jonathon D. Coey, Swathi Sukumar, Benjamin Lang, John McLauchlan, Steeve Boulant, Megan L. Stanifer, Connor G. G. Bamford
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interferon lambdas (IFNλ) (also known as type III IFNs) are critical cytokines that combat infection predominantly at barrier tissues, such as the lung, liver, and gastrointestinal tract. Humans have four IFNλs (1–4), where IFNλ1–3 show ~80%
Externí odkaz:
https://doaj.org/article/dfa5ef4c8962486d9e2125865902a27f
Autor:
Connor G. G. Bamford, Elihu Aranday-Cortes, Ricardo Sanchez-Velazquez, Catrina Mullan, Alain Kohl, Arvind H. Patel, Sam J. Wilson, John McLauchlan
Publikováno v:
Viruses, Vol 14, Iss 8, p 1655 (2022)
Natural hepatitis C virus (HCV) infection is restricted to humans, whereas other primates such as rhesus macaques are non-permissive for infection. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication
Externí odkaz:
https://doaj.org/article/bcb9c4931f2f42b7955a775ec23b24b8
Autor:
Connor G. G. Bamford, Lindsay Broadbent, Elihu Aranday-Cortes, Mary McCabe, James McKenna, David G. Courtney, Olivier Touzelet, Ahlam Ali, Grace Roberts, Guillermo Lopez Campos, David Simpson, Conall McCaughey, Derek Fairley, Ken Mills, Ultan F. Power, on behalf of the Breathing Together Investigators
Publikováno v:
Viruses, Vol 14, Iss 2, p 325 (2022)
SARS-CoV-2 can efficiently infect both children and adults, albeit with morbidity and mortality positively associated with increasing host age and presence of co-morbidities. SARS-CoV-2 continues to adapt to the human population, resulting in several
Externí odkaz:
https://doaj.org/article/7eb0dce777284585ab48e1334ebdc74c
Autor:
Connor G. G. Bamford
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Connor G. G. Bamford works in the fields of virology and innate immunity. In this mSphere of Influence article, he reflects on how three papers by Manry et al. (J. Manry, G. Laval, E. Patin, S. Fornarino, et al., J Exp Med 208:2747–2759, 2
Externí odkaz:
https://doaj.org/article/0a0cdaeef3324f9e934a878539a21c10
Autor:
Stephen H Bell, Danielle M Allen, Marina I Reyne, Jonathan F W Lock, Arthur Fitzgerald, Ashley Levickas, Andrew J Lee, Connor G G Bamford, Deirdre F Gilpin, John W McGrath
Publikováno v:
Letters in Applied Microbiology.
Wastewater Based Epidemiology (WBE) has become an integral part of the public health effort to track the levels of SARS-CoV-2 within communities. Detection of SARS-CoV-2 in wastewater can be challenging due to relatively low levels of virus within th
Publikováno v:
Bamford, C G G, de Souza, W M, Parry, R & Gifford, R J 2022, ' Comparative analysis of genome-encoded viral sequences reveals the evolutionary history of flavivirids (family Flaviviridae) ', Virus Evolution, vol. 8, no. 2 . https://doi.org/10.1093/ve/veac085
The flaviviruses (family Flaviviridae) are a group of positive-strand RNA viruses, many of which pose serious risks to human health on a global scale. Here, we calibrate the timeline of flavivirus evolution using flavivirus-derived DNA sequences iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ec1cf6a6b91450cd38e08ecaf1db05
https://pure.qub.ac.uk/en/publications/2d7abff6-0804-4451-9365-f5ea43cb0e34
https://pure.qub.ac.uk/en/publications/2d7abff6-0804-4451-9365-f5ea43cb0e34
Autor:
Diego Cantoni, Matthew J Murray, Mphatso D Kalemera, Samuel J Dicken, Lenka Stejskal, Georgina Brown, Spyros Lytras, Jonathon D Coey, James McKenna, Stephen Bridgett, David Simpson, Derek Fairley, Lucy G Thorne, Ann‐Kathrin Reuschl, Calum Forrest, Maaroothen Ganeshalingham, Luke Muir, Machaela Palor, Lisa Jarvis, Brian Willett, Ultan F Power, Laura E McCoy, Clare Jolly, Greg J Towers, Katie J Doores, David L Robertson, Adrian J Shepherd, Matthew B Reeves, Connor G G Bamford, Joe Grove
Publikováno v:
Cantoni, D, Murray, M J, Kalemera, M D, Dicken, S J, Stejskal, L, Brown, G, Lytras, S, Coey, J D, McKenna, J, Bridgett, S, Simpson, D, Fairley, D, Thorne, L G, Reuschl, A-K, Forrest, C, Ganeshalingham, M, Muir, L, Palor, M, Jarvis, L, Willett, B, Power, U F, McCoy, L E, Jolly, C, Towers, G J, Doores, K J, Robertson, D L, Shepherd, A J, Reeves, M B, Bamford, C G G & Grove, J 2022, ' Evolutionary remodelling of N-terminal domain loops fine-tunes SARS-CoV-2 spike ', EMBO Reports, vol. 23, no. 10, e54322 . https://doi.org/10.15252/embr.202154322
The emergence of SARS-CoV-2 variants has exacerbated the COVID-19 global health crisis. Thus far, all variants carry mutations in the spike glycoprotein, which is a critical determinant of viral transmission being responsible for attachment, receptor
Autor:
Connor G G Bamford, Elihu-Aranday Cortes, Ricardo Sanchez-Velazquez, Catrina Mullan, Alain Kohl, Arvind H. Patel, Sam J. Wilson, John McLauchlan
Natural hepatitis C virus (HCV) infection is restricted to humans whereas in other primates such as rhesus macaques, the virus is non-permissive. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c1c7ad81b7564df057ad2ecca70280
https://doi.org/10.1101/2022.05.12.491650
https://doi.org/10.1101/2022.05.12.491650