Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Connor G G, Bamford"'
Autor:
Lindsay Broadbent, Connor G. G. Bamford, Guillermo Lopez Campos, Sheerien Manzoor, David Courtney, Ahlam Ali, Olivier Touzelet, Conall McCaughey, Ken Mills, Ultan F. Power
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease-19 (COVID-19) pandemic, was identified in late 2019 and caused >5 million deaths by February 2022. To date, targeted antiviral interventions against CO
Externí odkaz:
https://doaj.org/article/4820500485534bfd92cf98d195b99d42
Autor:
Stephen H. Bell, Derek J. Fairley, Hannele Kettunen, Juhani Vuorenmaa, Juha Orte, Connor G. G. Bamford, John W. McGrath
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT Chemical methods of virus inactivation are used routinely to prevent viral transmission in both a personal hygiene capacity but also in at-risk environments like hospitals. Several virucidal products exist, including hand soaps, gels, and su
Externí odkaz:
https://doaj.org/article/aae110d45368444c8acbc3b201a8dab9
Autor:
Cuncai Guo, Dorothee Reuss, Jonathon D. Coey, Swathi Sukumar, Benjamin Lang, John McLauchlan, Steeve Boulant, Megan L. Stanifer, Connor G. G. Bamford
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Interferon lambdas (IFNλ) (also known as type III IFNs) are critical cytokines that combat infection predominantly at barrier tissues, such as the lung, liver, and gastrointestinal tract. Humans have four IFNλs (1–4), where IFNλ1–3 show ~80%
Externí odkaz:
https://doaj.org/article/dfa5ef4c8962486d9e2125865902a27f
Autor:
Andrew E Shaw, Suzannah J Rihn, Nardus Mollentze, Arthur Wickenhagen, Douglas G Stewart, Richard J Orton, Srikeerthana Kuchi, Siddharth Bakshi, Mila Rodriguez Collados, Matthew L Turnbull, Joseph Busby, Quan Gu, Katherine Smollett, Connor G G Bamford, Elena Sugrue, Paul C D Johnson, Ana Filipe Da Silva, Alfredo Castello, Daniel G Streicker, David L Robertson, Massimo Palmarini, Sam J Wilson
Publikováno v:
PLoS Biology, Vol 19, Iss 9, p e3001352 (2021)
Antiviral defenses can sense viral RNAs and mediate their destruction. This presents a challenge for host cells since they must destroy viral RNAs while sparing the host mRNAs that encode antiviral effectors. Here, we show that highly upregulated int
Externí odkaz:
https://doaj.org/article/93c6a324bb0649b4bf2748908f349e90
Autor:
Connor G. G. Bamford, Elihu Aranday-Cortes, Ricardo Sanchez-Velazquez, Catrina Mullan, Alain Kohl, Arvind H. Patel, Sam J. Wilson, John McLauchlan
Publikováno v:
Viruses, Vol 14, Iss 8, p 1655 (2022)
Natural hepatitis C virus (HCV) infection is restricted to humans, whereas other primates such as rhesus macaques are non-permissive for infection. To identify human and rhesus macaque genes that differ or share the ability to inhibit HCV replication
Externí odkaz:
https://doaj.org/article/bcb9c4931f2f42b7955a775ec23b24b8
Autor:
Connor G G Bamford
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009547 (2021)
Externí odkaz:
https://doaj.org/article/0479c0dc7ed44d15bfc766689ef29e2c
Autor:
Connor G. G. Bamford
Publikováno v:
mSphere, Vol 5, Iss 2 (2020)
ABSTRACT Connor G. G. Bamford works in the fields of virology and innate immunity. In this mSphere of Influence article, he reflects on how three papers by Manry et al. (J. Manry, G. Laval, E. Patin, S. Fornarino, et al., J Exp Med 208:2747–2759, 2
Externí odkaz:
https://doaj.org/article/0a0cdaeef3324f9e934a878539a21c10
Autor:
Connor G. G. Bamford, Lindsay Broadbent, Elihu Aranday-Cortes, Mary McCabe, James McKenna, David G. Courtney, Olivier Touzelet, Ahlam Ali, Grace Roberts, Guillermo Lopez Campos, David Simpson, Conall McCaughey, Derek Fairley, Ken Mills, Ultan F. Power, on behalf of the Breathing Together Investigators
Publikováno v:
Viruses, Vol 14, Iss 2, p 325 (2022)
SARS-CoV-2 can efficiently infect both children and adults, albeit with morbidity and mortality positively associated with increasing host age and presence of co-morbidities. SARS-CoV-2 continues to adapt to the human population, resulting in several
Externí odkaz:
https://doaj.org/article/7eb0dce777284585ab48e1334ebdc74c
Autor:
Stephen H Bell, Danielle M Allen, Marina I Reyne, Jonathan F W Lock, Arthur Fitzgerald, Ashley Levickas, Andrew J Lee, Connor G G Bamford, Deirdre F Gilpin, John W McGrath
Publikováno v:
Letters in Applied Microbiology.
Wastewater Based Epidemiology (WBE) has become an integral part of the public health effort to track the levels of SARS-CoV-2 within communities. Detection of SARS-CoV-2 in wastewater can be challenging due to relatively low levels of virus within th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0b85ff6f64e11a871762e76d3e8bb32
https://doi.org/10.1093/lambio/ovad047
https://doi.org/10.1093/lambio/ovad047
Autor:
Connor G G Bamford, Elihu Aranday-Cortes, Ines Cordeiro Filipe, Swathi Sukumar, Daniel Mair, Ana da Silva Filipe, Juan L Mendoza, K Christopher Garcia, Shaohua Fan, Sarah A Tishkoff, John McLauchlan
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007307 (2018)
As antimicrobial signalling molecules, type III or lambda interferons (IFNλs) are critical for defence against infection by diverse pathogens, including bacteria, fungi and viruses. Counter-intuitively, expression of one member of the family, IFNλ4
Externí odkaz:
https://doaj.org/article/cf343b4a4c164812bd8a9eb06ac01eca