Mechanics and differential healing outcomes of small and large defect injuries of the tendon-bone attachment in the rat rotator cuff

Autor: Anna Lia Sullivan, Ryan C. Locke, Rachel K. Klink, Connor C. Leek, James E. Carpenter, Megan L. Killian

Publikováno v: Connective Tissue Research. 64:262-273

Rotator cuff tear size affects clinical outcomes following rotator cuff repair and is correlated with the risk of recurrent tendon defects. This study aimed to understand if and how the initial defect size influences the structural and mechanical out

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8b7ebb0e5c145e49bd7040db9619e7
https://doi.org/10.1080/03008207.2022.2152334

Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments

Autor: Connor C Leek, David M. Ornitz, Jaysheel Bhavsar, Megan C Smith, Jaclyn M. Soulas, Shawn W. Polson, Ryan C. Locke, Elahe Ganji, Megan L. Killian, Iman Bhattacharya

Publikováno v: Dev Dyn

Background The growth of most bony tuberosities, like the deltoid tuberosity (DT), rely on the transmission of muscle forces at the tendon-bone attachment during skeletal growth. Tuberosities distribute muscle forces and provide mechanical leverage a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4b2756919ccf44c21b70e0fd043e88e
https://doi.org/10.1002/dvdy.383

Author Reply to Peer Reviews of Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments

Autor: Megan L. Killian, David M. Ornitz, Shawn W. Polson, Jaysheel D. Bhavsar, Megan C. Smith, Ryan C. Locke, Elahe Ganji, Iman Bhattacharya, Jaclyn M. Soulas, Connor C. Leek

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a23fd82dd7ea984284d0df9401e8a9b
https://doi.org/10.15252/rc.2022446756

Mechanics and Differential Healing Outcomes of Small and Large Defect Injuries of the Tendon-Bone Attachment in the Rat Rotator Cuff

Autor: Connor C Leek, Rachel K. Klink, Megan L. Killian, Ryan C. Locke, Anna Lia Sullivan

The size of rotator cuff tears affects clinical outcomes following rotator cuff repair and is correlated with risk of re-injury. This study aimed to understand how defect size influences the structural and mechanical outcomes of the injured rotator c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fda1c825c6d1287ea0b498499217db91
https://doi.org/10.1101/2020.07.03.184499

Role of sex as a biological variable in neonatal alveolar macrophages.

Autor: Leek C; Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA., Cantu A; Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA., Sonti S; Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA., Gutierrez MC; Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA., Eldredge L; Department of Pediatrics, Division of Pediatric Pulmonology, University of Washington School of Medicine, Seattle Children's Hospital, WA, USA., Sajti E; Department of Pediatrics, Division of Neonatology, University of California San Diego, San Diego, CA, USA., Xu HN; Britton Chance Laboratory of Redox Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lingappan K; Department of Pediatrics, Division of Neonatology, Children's Hospital of Philadelphia, University of Pennsylvania, PA, USA. Electronic address: lingappank@chop.edu.

Publikováno v: Redox biology [Redox Biol] 2024 Sep; Vol. 75, pp. 103296. Date of Electronic Publication: 2024 Aug 02.