Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Connor A Howe"'
Autor:
Gustavo A. Vizcardo-Galindo, Connor A. Howe, Ryan L. Hoiland, Howard H. Carter, Christopher K. Willie, Philip N. Ainslie, Joshua C. Tremblay
Publikováno v:
High Altitude Medicine & Biology. 24:27-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382213bf93823c5401bf9f5f348b118f
https://doi.org/10.1089/ham.2022.0107
https://doi.org/10.1089/ham.2022.0107
Autor:
Jay M. J. R. Carr, Connor A. Howe, Travis D. Gibbons, Michael M. Tymko, Andrew R. Steele, Gustavo A. Vizcardo-Galindo, Joshua C. Tremblay, Philip N. Ainslie
Publikováno v:
Journal of Applied Physiology. 133:1356-1367
We assessed steady-state hypercapnic cerebrovascular reactivity and cerebral endothelium-dependent function, with and without α1-adrenergic blockade (Prazosin), in a placebo-controlled, double-blind, and randomized study, to assess the contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6c1d4ec9d556f2b8ec924615ffbd43
https://doi.org/10.1152/japplphysiol.00400.2022
https://doi.org/10.1152/japplphysiol.00400.2022
Autor:
Jay MJR Carr, Philip N Ainslie, David B MacLeod, Joshua C Tremblay, Daniela Nowak-Flück, Connor A Howe, Mike Stembridge, Alexander Patrician, Geoff B Coombs, Benjamin S Stacey, Damian M Bailey, Daniel J Green, Ryan L Hoiland
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 43:99-114
This study investigated the influence of acute reductions in arterial O2 content (CaO2) via isovolumic haemodilution on global cerebral blood flow (gCBF) and cerebrovascular CO2 reactivity (CVR) in 11 healthy males (age; 28 ± 7 years: body mass inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e240a0f8e294cee21d2691e7c6f9b6b
https://doi.org/10.1177/0271678x221119442
https://doi.org/10.1177/0271678x221119442
Autor:
Michael Furian, Mathilde Ulliel-Roche, Connor A Howe, Fanny Zerizer, Mathieu Marillier, Anne Catherine Bernard, Ivan Hancco, Benoit Champigneulle, Sébastien Baillieul, Emeric Stauffer, Aurelien P Pichon, Stephane Doutreleau, Samuel Verges, Julien Brugniaux
Permanent residence at high-altitude and chronic mountain sickness (CMS) may alter the cerebrovascular homeostasis and orthostatic responses. 15/13/17 healthy participants living at sea-level (LL), 3,800m (HL3800m) and 5,100m (HL5100m), respectively,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be6178ed44a018aa260328b66482bf99
https://doi.org/10.21203/rs.3.rs-2952047/v1
https://doi.org/10.21203/rs.3.rs-2952047/v1
Autor:
Gustavo Vizcardo-Galindo, Ryan L. Hoiland, Christopher Gasho, Francisco C. Villafuerte, Kaitlyn Tymko, Courtney Tymko, James D. Anholm, John D. Akins, Philip N. Ainslie, Michael M. Tymko, Travis D. Gibbons, Rachel Stone, Geoff B. Coombs, Mike Stembridge, Connor A. Howe, Damian M. Bailey, Joshua C. Tremblay, Tony G. Dawkins, Alexander Patrician, Benjamin S. Stacey, Rómulo Figueroa-Mujíca
Publikováno v:
Chest. 161:1022-1035
BACKGROUND: Increasing iron bioavailability attenuates hypoxic pulmonary vasoconstriction in both lowlanders and Sherpas at high altitude. In contrast, the pulmonary vasculature of Andeans with chronic mountain sickness (CMS) is resistant to iron adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b782c7ad08d714e67219d696a015ac2c
https://doi.org/10.1016/j.chest.2021.08.075
https://doi.org/10.1016/j.chest.2021.08.075
Autor:
Michael M. Tymko, Christopher K. Willie, Connor A. Howe, Ryan L. Hoiland, Rachel M. Stone, Kaitlyn Tymko, Courtney Tymko, David MacLeod, James D. Anholm, Christopher Gasho, Francisco Villafuerte, Gustavo Vizcardo-Galindo, Romulo Figueroa-Mujica, Trevor A. Day, Jordan D. Bird, Glen E. Foster, Craig D. Steinback, Julien V. Brugniaux, Benoit Champigneulle, Emeric Stauffer, Stephane Doutreleau, Samuel Verges, Erik R. Swenson, Philip N. Ainslie
Publikováno v:
Journal of Applied Physiology
Journal of Applied Physiology, 2022, 132 (2), pp.575-580. ⟨10.1152/japplphysiol.00757.2021⟩
Journal of Applied Physiology, 2022, 132 (2), pp.575-580. ⟨10.1152/japplphysiol.00757.2021⟩
International audience; High-altitude exposure results in a hyperventilatory-induced respiratory alkalosis followed by renal compensation (bicarbonaturia) to return arterial blood pH (pHa) toward sea-level values. However, acid-base balance has not b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a06759ec21ddc2a913ae0344d8acadd
https://doi.org/10.1152/japplphysiol.00757.2021
https://doi.org/10.1152/japplphysiol.00757.2021
Autor:
Benjamin S. Stacey, Ryan L. Hoiland, Hannah G. Caldwell, Connor A. Howe, Tyler Vermeulen, Michael M. Tymko, Gustavo A. Vizcardo‐Galindo, Daniella Bermudez, Rómulo J. Figueroa‐Mujíica, Christopher Gasho, Edouard Tuaillon, Christophe Hirtz, Sylvain Lehmann, Nicola Marchi, Hayato Tsukamoto, Francisco C. Villafuerte, Philip N. Ainslie, Damian M. Bailey
KEY POINTS: High-altitude (HA) hypoxia has the potential to alter the structural-functional integrity of the neurovascular unit (NVU) in humans. For the first time, we examined to what extent chronic and lifelong hypoxia impacts multimodal biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ea372579d298c4f3af53e2e8ff10ca
https://hdl.handle.net/20.500.12866/13113
https://hdl.handle.net/20.500.12866/13113
Autor:
Hannah G Caldwell, Ryan L Hoiland, Kurt J Smith, Patrice Brassard, Anthony R Bain, Michael M Tymko, Connor A Howe, Jay MJR Carr, Benjamin S Stacey, Damian M Bailey, Audrey Drapeau, Mypinder S Sekhon, David B MacLeod, Philip N Ainslie
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 42:559-571
This study investigated trans-cerebral internal jugular venous-arterial bicarbonate ([HCO3−]) and carbon dioxide tension (PCO2) exchange utilizing two separate interventions to induce acidosis: 1) acute respiratory acidosis via elevations in arteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1654d072eafac15c20b12ce19a658131
https://doi.org/10.1177/0271678x211065924
https://doi.org/10.1177/0271678x211065924
Autor:
Jay M J R, Carr, Connor A, Howe, Travis D, Gibbons, Michael M, Tymko, Andrew R, Steele, Gustavo A, Vizcardo-Galindo, Joshua C, Tremblay, Philip N, Ainslie
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 133(6)
We assessed hypercapnic cerebrovascular reactivity (CVR) and endothelium-dependent function [cerebral shear-mediated dilation (cSMD)] in the internal carotid artery (ICA) with and without systemic α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf4a15239c146dce8e2508aecd751025
https://pubmed.ncbi.nlm.nih.gov/36326471
https://pubmed.ncbi.nlm.nih.gov/36326471
Autor:
Jay Mjr, Carr, Philip N, Ainslie, David B, MacLeod, Joshua C, Tremblay, Daniela, Nowak-Flück, Connor A, Howe, Mike, Stembridge, Alexander, Patrician, Geoff B, Coombs, Benjamin S, Stacey, Damian M, Bailey, Daniel J, Green, Ryan L, Hoiland
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 43(1)
This study investigated the influence of acute reductions in arterial O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e80277b5f7462c3088f6f14cb604df6
https://pubmed.ncbi.nlm.nih.gov/36131560
https://pubmed.ncbi.nlm.nih.gov/36131560