Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Connon I. Thomas"'
Publikováno v:
eLife, Vol 12 (2023)
Postsynaptic mitochondria are critical for the development, plasticity, and maintenance of synaptic inputs. However, their relationship to synaptic structure and functional activity is unknown. We examined a correlative dataset from ferret visual cor
Externí odkaz:
https://doaj.org/article/5e51dd1cd47c477a9e36e813ebb9743f
Autor:
Christian Keine, Mohammed Al-Yaari, Tamara Radulovic, Connon I Thomas, Paula Valino Ramos, Debbie Guerrero-Given, Mrinalini Ranjan, Holger Taschenberger, Naomi Kamasawa, Samuel M Young Jr
Publikováno v:
eLife, Vol 11 (2022)
Synapses contain a limited number of synaptic vesicles (SVs) that are released in response to action potentials (APs). Therefore, sustaining synaptic transmission over a wide range of AP firing rates and timescales depends on SV release and replenish
Externí odkaz:
https://doaj.org/article/72cde114cf3040d9b27dec89dc94dd1c
Autor:
Debbie Guerrero-Given, Seth L. Goldin, Connon I. Thomas, Skylar A. Anthony, Diego Jerez, Naomi Kamasawa
Publikováno v:
Frontiers in Neuroanatomy, Vol 16 (2022)
Integral membrane proteins such as ion channels, transporters, and receptors shape cell activity and mediate cell-to-cell communication in the brain. The distribution, quantity, and clustering arrangement of those proteins contribute to the physiolog
Externí odkaz:
https://doaj.org/article/6ed72b6026444fb09f0d4dfbade5e858
Autor:
Ye Sun, Naomi Kamasawa, Nicolai T. Urban, Connon I. Thomas, Xun Tu, Lesley A. Colgan, Ryohei Yasuda
Publikováno v:
Microscopy Today. 29:34-39
In correlative light and electron microscopy (CLEM) workflows, identifying the same sub-cellular features in tissue by both light (LM) and electron microscopy (EM) remains a challenge. Furthermore, use of cryo-fixation for EM is desirable to capture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c9a0a2daef689e84e1216ea3a4b089
https://doi.org/10.1017/s1551929521001073
https://doi.org/10.1017/s1551929521001073
Autor:
Christian Keine, Mohammed Al-Yaari, Tamara Radulovic, Connon I Thomas, Paula Valino Ramos, Debbie Guerrero-Given, Mrinalini Ranjan, Holger Taschenberger, Naomi Kamasawa, Samuel M Young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7af59d6ada0dc591cc8ce1b47dce9f
https://doi.org/10.7554/elife.81505.sa2
https://doi.org/10.7554/elife.81505.sa2
Autor:
Priyadharishini Veeraraghavan, Matthias Lübbert, Toshihisa Ohtsuka, Tamara Radulovic, Samuel M. Young, Debbie Guerrero-Given, R. Oliver Goral, Naomi Kamasawa, Mónica S. Montesinos, Connon I. Thomas, Wei Dong, Kevin M Goff
Publikováno v:
J Physiol
Key points CAST/ELKS are positive regulators of presynaptic growth and are suppressors of active zone expansion at the developing mouse calyx of Held. CAST/ELKS regulate all three CaV 2 subtype channel levels in the presynaptic terminal and not just
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbbaf6640fc0519ff90914aad47530e
https://doi.org/10.1113/jp279736
https://doi.org/10.1113/jp279736
Autor:
Sabrina Tazerart, Roberto Araya, Maxime G. Blanchard, Diana E. Mitchell, Soledad Miranda-Rottmann, Connon I. Thomas, Naomi Kamasawa, Bruno Navea Pina
Dendritic spines are the main receptacles of excitatory information in the brain. Their particular morphology, with a small head connected to the dendrite by a slender neck, has inspired theoretical and experimental work to understand how these struc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47747401bf52ab0aa1ccdc2b90d0d0b3
https://doi.org/10.1101/2021.09.07.459293
https://doi.org/10.1101/2021.09.07.459293
Autor:
Gregory T. Macleod, Michal Stawarski, A.W.C. Lau, Touhid Feghhi, Naomi Kamasawa, Connon I. Thomas, Roberto X. Hernandez
Publikováno v:
Biophys J
At chemical synapses, synaptic vesicles release their acidic contents into the cleft, leading to the expectation that the cleft should acidify. However, fluorescent pH probes targeted to the cleft of conventional glutamatergic synapses in both fruit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a822f1554a3318d2917b3be572b1be94
https://pubmed.ncbi.nlm.nih.gov/34798062
https://pubmed.ncbi.nlm.nih.gov/34798062
Autor:
Connon I. Thomas, Michal Stawarski, A.W.C. Lau, Gregory T. Macleod, Touhid Feghhi, Roberto X. Hernandez, Naomi Kamasawa
At chemical synapses, synaptic vesicles release their acidic contents into the cleft leading to the expectation that the cleft should acidify. However, fluorescent pH probes targeted to the cleft of conventional glutamatergic synapses in both fruit f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0826e25632d2894addc674a112f7870
https://doi.org/10.1101/2021.06.30.450624
https://doi.org/10.1101/2021.06.30.450624
Presynaptic Mitochondria Volume and Abundance Increase during Development of a High-Fidelity Synapse
Autor:
Christian Keine, Morgan Musgrove, Debbie Guerrero-Given, Connon I. Thomas, Rachel Satterfield, Satoko Okayama, Samuel M. Young, Naomi Kamasawa
Publikováno v:
The Journal of Neuroscience. 39:7994-8012
The calyx of Held, a large glutamatergic presynaptic terminal in the auditory brainstem undergoes developmental changes to support the high action-potential firing rates required for auditory information encoding. In addition, calyx terminals are mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb33fce8c10ae1d6afe426ab584ca13
https://doi.org/10.1523/jneurosci.0363-19.2019
https://doi.org/10.1523/jneurosci.0363-19.2019