Heart rate and autonomic biomarkers distinguish convulsive epileptic vs. functional or dissociative seizures.

Autor: Ryan JM; Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, United States., Wagner KT; Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, United States., Yerram S; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Concannon C; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Lin JX; School of Medicine, University of Rochester Medical Center, Rochester, NY 14642, United States., Rooney P; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Hanrahan B; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Titoff V; Department of Neurology-Epilepsy, SUNY Upstate Medical University, Syracuse, NY 13210, United States; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Connolly NL; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Cranmer R; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., DeMaria N; Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, United States., Xia X; Clinical Cardiology Research Center Medicine-Cardiology, University of Rochester Medical Center, Rochester, NY 14642, United States., Mykins B; Clinical Cardiology Research Center Medicine-Cardiology, University of Rochester Medical Center, Rochester, NY 14642, United States., Erickson S; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Couderc JP; Clinical Cardiology Research Center Medicine-Cardiology, University of Rochester Medical Center, Rochester, NY 14642, United States., Schifitto G; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Hughes I; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Wang D; Department of Public Health, SUNY Upstate Medical University, Syracuse, NY 13210, United States., Erba G; Department of Neurology, University of Rochester Medical Center, Rochester, NY 14642, United States., Auerbach DS; Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY 13210, United States. Electronic address: aueracd@upstate.edu.

Publikováno v: Seizure [Seizure] 2023 Oct; Vol. 111, pp. 178-186. Date of Electronic Publication: 2023 Aug 25.

Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation.

Autor: Belgrad, Jillian, Fakih, Hassan H., Khvorova, Anastasia

Publikováno v: Nucleic Acid Therapeutics; Apr2024, Vol. 34 Issue 2, p52-72, 21p

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From Failure to Meet the Clinical Endpoint to U.S. Food and Drug Administration Approval: 15th Antisense Oligonucleotide Therapy Approved Qalsody (Tofersen) for Treatment of SOD1 Mutated Amyotrophic Lateral Sclerosis.

Autor: van Roon-Mom, Willeke, Ferguson, Chantal, Aartsma-Rus, Annemieke

Publikováno v: Nucleic Acid Therapeutics; Aug2023, Vol. 33 Issue 4, p234-237, 4p

12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.

Autor: Welgus HG, Connolly NL, Senior RM

Publikováno v: The Journal of clinical investigation [J Clin Invest] 1986 May; Vol. 77 (5), pp. 1675-81.