Extracellular Vesicles in the Synovial Joint: Is there a Role in the Pathophysiology of Osteoarthritis?

Autor: Esa A, Connolly KD, Williams R, Archer CW

Publikováno v: Malaysian Orthopaedic Journal, Vol 13, Iss 1, Pp 1-7 (2019)

The role of extracellular vesicles (EV) in osteoarthritis has become the focus of much research. These vesicles were isolated from several cell types found in synovial joint including chondrocytes and synovium. As articular cartilage is an avascular

Externí odkaz: https://doaj.org/article/57df82aaea564c8495542cc79572cf69

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Role of adipocyte-derived extracellular vesicles in vascular inflammation.

Autor: Connolly KD; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, CF5 2YB, United Kingdom., Rees DA; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff, CF24 4HQ, United Kingdom., James PE; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, CF5 2YB, United Kingdom. Electronic address: pjames@cardiffmet.ac.uk.

Publikováno v: Free radical biology & medicine [Free Radic Biol Med] 2021 Aug 20; Vol. 172, pp. 58-64. Date of Electronic Publication: 2021 May 28.

Evidence for Adipocyte-Derived Extracellular Vesicles in the Human Circulation.

Autor: Connolly KD; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom., Wadey RM; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom., Mathew D; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom.; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom., Johnson E; Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom., Rees DA; Neuroscience and Mental Health Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom., James PE; School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, United Kingdom.

Publikováno v: Endocrinology [Endocrinology] 2018 Sep 01; Vol. 159 (9), pp. 3259-3267.

Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia.

Autor: Connolly KD; Institute of Molecular and Experimental Medicine School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Willis GR; Institute of Molecular and Experimental Medicine School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Datta DB; Lipid Unit, Llandough Hospital, Cardiff CF64 2XX, United Kingdom., Ellins EA; Institute of Molecular and Experimental Medicine School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom Institute of Life Sciences, College of Medicine, Swansea University, Singleton Park, Swansea SA2 8PP, United Kingdom., Ladell K; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Price DA; Institute of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., Guschina IA; School of Biosciences, Cardiff University, Cardiff CF10 3AX, United Kingdom., Rees DA; Institute of Molecular and Experimental Medicine School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom., James PE; Institute of Molecular and Experimental Medicine School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom.

Publikováno v: Journal of lipid research [J Lipid Res] 2014 Oct; Vol. 55 (10), pp. 2064-72. Date of Electronic Publication: 2014 Aug 13.