Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Connolly, James P.R."'
Publikováno v:
In Trends in Microbiology May 2020 28(5):360-371
Bacterial pathogens employ diverse fitness and virulence mechanisms to gain an advantage in competitive niches. These lifestyle-specific traits require integration into the regulatory network of the cell and are often controlled by pre-existing trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::31fe2672279b5d2e7abc9cd2f1a9dfc1
https://eprints.gla.ac.uk/209013/1/209013.pdf
https://eprints.gla.ac.uk/209013/1/209013.pdf
Autor:
Zambelloni, Riccardo, Connolly, James P.R., Huerta Uribe, Alejandro, Burgess, Karl, Marquez, Rodolfo, Roe, Andrew J.
Publikováno v:
Molecular Microbiology
Zambelloni, R, Connolly, J P R, Uribe, A H, Burgess, K, Marquez, R & Roe, A J 2017, ' Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition ', Molecular Microbiology, vol. 105, no. 4, pp. 606-619 . https://doi.org/10.1111/mmi.13719
Zambelloni, R, Connolly, J P R, Uribe, A H, Burgess, K, Marquez, R & Roe, A J 2017, ' Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition ', Molecular Microbiology, vol. 105, no. 4, pp. 606-619 . https://doi.org/10.1111/mmi.13719
Anti-virulence (AV) compounds are a promising alternative to traditional antibiotics for fighting bacterial infections. The Type Three Secretion System (T3SS) is a well-studied and attractive AV target, given that it is widespread in more than 25 spe
Bacterial pathogens emerge by adapting mechanisms of virulence, differentiating them from their nonpathogenic progenitor. Virulence factors are often encoded on accessory genomic elements not part of the core genome and therefore must be integrated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::0d99436e04a39ce16e93bdb0823c263a
https://eprints.gla.ac.uk/193324/1/193324.pdf
https://eprints.gla.ac.uk/193324/1/193324.pdf
Autor:
Irvine, Sharon, Bunk, Boyke, Bayes, Hannah K., Spröer, Cathrin, Connolly, James P.R., Six, Anne, Evans, Thomas J., Roe, Andrew J., Overmann, Jörg, Walker, Daniel
Publikováno v:
Microbial Genomics
Phenotypic change is a hallmark of bacterial adaptation during chronic infection. In the case of chronic Pseudomonas aeruginosa lung infection in patients with cystic fibrosis, well-characterized phenotypic variants include mucoid and small colony va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6d026c72485f9a50183763571246555c
https://eprints.gla.ac.uk/181661/1/181661.pdf
https://eprints.gla.ac.uk/181661/1/181661.pdf
Autor:
Connolly, James P.R.
Publikováno v:
IndraStra Global.
Escherichia coli is a diverse bacterial species found largely as a harmless commensal in the gastrointestinal tract of warm-blooded mammals. However, an array of highly adapted E. coli pathotypes have evolved over time capable of causing a variety of
Autor:
Beckham, Katherine S.H., Connolly, James P.R., Ritchie, Jennifer M., Wang, Dai, Gawthorne, Jayde A., Tahoun, Amin, Gally, David L., Burgess, Karl, Burchmore, Richard J., Smith, Brian O., Beatson, Scott A., Byron, Olwyn, Wolfe, Alan J., Douce, Gillian, Roe, Andrew J.
Classical studies have focused on the role that individual regulators play in controlling virulence gene expression. An emerging theme, however, is that bacterial metabolism also plays a key role in this process. Our previous work identified a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::bc8d6197c3709c04407d61f832947305
https://eprints.gla.ac.uk/93982/2/93982.pdf
https://eprints.gla.ac.uk/93982/2/93982.pdf
Autor:
Ormsby, Michael J., Johnson, Síle A., Carpena, Nuria, Meikle, Lynsey M., Goldstone, Robert J., McIntosh, Anne, Wessel, Hannah M., Hulme, Heather E., McConnachie, Ceilidh C., Connolly, James P.R., Roe, Andrew J., Hasson, Conor, Boyd, Joseph, Fitzgerald, Eamonn, Gerasimidis, Konstantinos, Morrison, Douglas, Hold, Georgina L., Hansen, Richard, Walker, Daniel, Smith, David G.E.
Publikováno v:
Cell Reports; Feb2020, Vol. 30 Issue 7, p2297-2297, 1p