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Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Autor: Bien, Stephanie A, Su, Yu-Ru, Conti, David V, Harrison, Tabitha A, Qu, Conghui, Guo, Xingyi, Lu, Yingchang, Albanes, Demetrius, Auer, Paul L, Banbury, Barbara L, Berndt, Sonja I, Bézieau, Stéphane, Brenner, Hermann, Buchanan, Daniel D, Caan, Bette J, Campbell, Peter T, Carlson, Christopher S, Chan, Andrew T, Chang-Claude, Jenny, Chen, Sai, Connolly, Charles M, Easton, Douglas F, Feskens, Edith JM, Gallinger, Steven, Giles, Graham G, Gunter, Marc J, Hampe, Jochen, Huyghe, Jeroen R, Hoffmeister, Michael, Hudson, Thomas J, Jacobs, Eric J, Jenkins, Mark A, Kampman, Ellen, Kang, Hyun Min, Kühn, Tilman, Küry, Sébastien, Lejbkowicz, Flavio, Le Marchand, Loic, Milne, Roger L, Li, Li, Li, Christopher I, Lindblom, Annika, Lindor, Noralane M, Martín, Vicente, McNeil, Caroline E, Melas, Marilena, Moreno, Victor, Newcomb, Polly A, Offit, Kenneth, Pharaoh, Paul DP, Potter, John D, Qu, Chenxu, Riboli, Elio, Rennert, Gad, Sala, Núria, Schafmayer, Clemens, Scacheri, Peter C, Schmit, Stephanie L, Severi, Gianluca, Slattery, Martha L, Smith, Joshua D, Trichopoulou, Antonia, Tumino, Rosario, Ulrich, Cornelia M, Van Duijnhoven, Fränzel JB, Van Guelpen, Bethany, Weinstein, Stephanie J, White, Emily, Wolk, Alicja, Woods, Michael O, Wu, Anna H, Abecasis, Goncalo R, Casey, Graham, Nickerson, Deborah A, Gruber, Stephen B, Hsu, Li, Zheng, Wei, Peters, Ulrike

Genome-wide association studies have reported 56 independently associated colorectal cancer (CRC) risk variants, most of which are non-coding and believed to exert their effects by modulating gene expression. The computational method PrediXcan uses c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7203ea21b0d84e45bcfb4faa7239a8bd

Correction to: Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.

Autor: Bien SA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA. sbien@fredhutch.org., Su YR; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Conti DV; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA.; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Harrison TA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Qu C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Guo X; Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Lu Y; Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA., Albanes D; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA., Auer PL; Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, 53205, USA., Banbury BL; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Berndt SI; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA., Bézieau S; Centre Hospitalier Universitaire Hotel-Dieu, 44093, Nantes, France.; Service de Génétique Médicale, Centre Hospitalier Universitaire (CHU), 44093, Nantes, France., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120, Heidelberg, Germany.; German Cancer Consortium (DKTK), 69120, Heidelberg, Germany., Buchanan DD; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia.; Colorectal Oncogenomics Group, Department of Pathology, University of Melbourne, Melbourne, VIC, 3010, Australia.; Genetic Medicine and Familial Cancer Centre, The Royal Melbourne Hospital, Parkville, VIC, 3010, Australia., Caan BJ; Division of Research, Kaiser Permanente Medical Care Program of Northern California, Oakland, CA, 94612, USA., Campbell PT; Epidemiology Research Program, American Cancer Society, Atlanta, GA, 30329-4251, USA., Carlson CS; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Chan AT; Division of Gastroenterology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Chang-Claude J; Unit of Genetic Epidemiology, Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany.; Genetic Tumour Epidemiology Group, University Medical Center Hamburg-Eppendorf, University Cancer Center Hamburg, 20246, Hamburg, Germany., Chen S; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA., Connolly CM; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Easton DF; Department of Public Health and Primary Care School of Clinical Medicine, University of Cambridge, Cambridge, England, 01223, UK., Feskens EJM; Division of Human Nutrition, Wageningen University & Research, Wageningen, The Netherlands., Gallinger S; Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, 1X5, Canada., Giles GG; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia.; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, 3004, Australia., Gunter MJ; Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark., Hampe J; Medical Department 1, University Hospital Dresden, TU Dresden, 01307, Dresden, Germany., Huyghe JR; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Hoffmeister M; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120, Heidelberg, Germany., Hudson TJ; Ontario Institute for Cancer Research, Toronto, ON, Canada.; AbbVie Inc, 1500 Seaport Blvd, Redwood City, CA, 94063, USA., Jacobs EJ; Epidemiology Research Program, American Cancer Society, Atlanta, GA, 30329-4251, USA., Jenkins MA; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia., Kampman E; Division of Human Nutrition, Wageningen University & Research, Wageningen, The Netherlands., Kang HM; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA., Kühn T; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Küry S; Centre Hospitalier Universitaire Hotel-Dieu, 44093, Nantes, France., Lejbkowicz F; Clalit Health Services National Israeli Cancer Control Center, 34361, Haifa, Israel.; Department of Community Medicine and Epidemiology, Carmel Medical Center, 34361, Haifa, Israel., Le Marchand L; University of Hawai'i Cancer Center, Honolulu, Hawaii, 96813, USA., Milne RL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, VIC, 3010, Australia.; Cancer Epidemiology & Intelligence Division, Cancer Council Victoria, Melbourne, 3004, Australia., Li L; Department of Family Medicine and Community Health, Case Western Reserve University, Cleveland, OH, 44106, USA., Li CI; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Lindblom A; Department of Clinical Genetics, Karolinska University Hospital Solna, 171 77, Stockholm, Sweden.; Department of Molecular Medicine and Surgery, Karolinska Institutet Solna, 171 77, Stockholm, Sweden., Lindor NM; Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, AZ, 85259, USA., Martín V; Research Group on Gene-Environment Interactions and Health, (GIIGAS). Institute of Biomedicine (IBIOMED), University of León, León, Spain.; CIBER Epidemiología y Salud Pública (CIBERESP), 28029, Madrid, Spain., McNeil CE; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA., Melas M; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA., Moreno V; CIBER Epidemiología y Salud Pública (CIBERESP), 28029, Madrid, Spain.; Catalan Institute of Oncology, Bellvitge Biomedical Research Institute (IDIBELL), 08028, Barcelona, Spain.; University of Barcelona, 08007, Barcelona, Spain., Newcomb PA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Offit K; Department of Medicine, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Pharaoh PDP; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge, Cambridge, CB2 1TN, UK., Potter JD; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Qu C; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA., Riboli E; School of Public Health, Imperial College London, London, UK., Rennert G; Clalit Health Services National Israeli Cancer Control Center, 34361, Haifa, Israel.; Department of Community Medicine and Epidemiology, Carmel Medical Center, 34361, Haifa, Israel., Sala N; Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, 08908, Barcelona, Spain.; Molecular Epidemiology Group, Translational Research Laboratory, Catalan Institute of Oncology-IDIBELL, L'Hospitalet de Llobregat, 08908, Barcelona, Spain., Schafmayer C; Department of General and Thoracic Surgery, University Hospital Schleswig-Holstein, Campus Kiel, 24118, Kiel, Germany., Scacheri PC; Department of Genetics and Genome Sciences, Case Western Reserve University, Cleveland, OH, 44106, USA., Schmit SL; Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa, FL, 33612, USA.; Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center and Research Institute, Inc, Tampa, FL, 33612, USA., Severi G; Centre for Research in Epidemiology and Population Health Institut de Cancérologie Gustave Roussy, Villejuif, France., Slattery ML; Department of Internal Medicine, University of Utah, Salt Lake City, UT, USA., Smith JD; Department Genome Sciences, University of Washington, 98195, Seattle, WA, USA., Trichopoulou A; Hellenic Health Foundation, 13 Kaisareias & Alexandroupoleos, 115 27, Athens, Greece.; WHO Collaborating Center for Nutrition and Health, Unit of Nutritional Epidemiology and Nutrition in Public Health, Department of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, 115 27, Athens, Greece., Tumino R; Affiliation Cancer Registry, Department of Prevention, Azienda Sanitaria Provinciale di Ragusa, Ragusa, Italy., Ulrich CM; Population Sciences, Huntsman Cancer Institute, Salt Lake City, UT, 84112, USA., van Duijnhoven FJB; Division of Human Nutrition, Wageningen University & Research, Wageningen, The Netherlands., Van Guelpen B; Department of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden., Weinstein SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, 20892, USA., White E; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Wolk A; Institute of Environmental Medicine, Karolinska Institutet Solna, 17177, Stockholm, Sweden.; Department of Surgical Sciences, Uppsala University, 75121, Uppsala, Sweden., Woods MO; Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, Saint John's, NL, A1B 3V6, Canada., Wu AH; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA.; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, 90033, USA., Abeçasis GR; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA., Casey G; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, 22908, USA., Nickerson DA; Department Genome Sciences, University of Washington, 98195, Seattle, WA, USA., Gruber SB; USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, 90089, USA., Hsu L; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Zheng W; Division of Epidemiology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA.; Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN, 37232, USA., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.

Publikováno v: Human genetics [Hum Genet] 2019 Jul; Vol. 138 (7), pp. 789-791.