Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Connie S. Chen"'
Autor:
Vicki Sutherland, Sangeeta Khare, Steven Foley, Xue Liang, Connie S. Chen, Alexander V. Alekseyenko, José E. Manautou, Howard Young, Frank Burns, Alan Wilson, Charlene A. McQueen, Sam Forry, Donna L. Mendrick, Donald J. Tweedie, Carl Cerniglia, Rod Dietert, Donna Gulezian
Publikováno v:
Toxicol Sci
There is an increasing awareness that the gut microbiome plays a critical role in human health and disease, but mechanistic insights are often lacking. In June 2018, the Health and Environmental Sciences Institute (HESI) held a workshop, “The Gut M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b552e9ad4aa035da554a05fecbc882
https://pubmed.ncbi.nlm.nih.gov/32658296
https://pubmed.ncbi.nlm.nih.gov/32658296
Publikováno v:
Cancer. 115:1563-1575
BACKGROUND: The limited antioxidative capacity of the fetus renders it more susceptible to reactive oxygen species (ROS), and possibly to ROS-mediated cancer initiation or promotion in utero. METHODS: To test this hypothesis, pregnant cancer-prone p5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe11adedb2e32009ea89e15d70276f8
https://doi.org/10.1002/cncr.24130
https://doi.org/10.1002/cncr.24130
Autor:
Peter G. Wells, Connie S. Chen
Publikováno v:
Carcinogenesis. 27:1358-1368
The limited antioxidative capacity of the embryo and fetus may increase their risk for cancer initiation and/or promotion by reactive oxygen species (ROS)-mediated oxidative DNA damage and/or signaling. To determine if cancer can originate in utero,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d189efc8486c3bec0a9a21f0d131882
https://doi.org/10.1093/carcin/bgi325
https://doi.org/10.1093/carcin/bgi325
Autor:
Rebecca R. Laposa, Julia Kennedy, Michael J. Wiley, Yadvinder Bhuller, Peter G. Wells, Connie S. Chen, Gordon P. McCallum, Sonja Kasapinovic, Christopher J. Nicol, Winnie Jeng, Perry M. Kim, Toufan Parman, Andrea W. Wong
Publikováno v:
Toxicology and Applied Pharmacology. 207:354-366
Developmental pathologies may result from endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS), which oxidatively damage cellular macromolecules and/or alter signal transduction. This minireview focuses upon several model drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c5996bc8936632237bd84da03d261a
https://doi.org/10.1016/j.taap.2005.01.061
https://doi.org/10.1016/j.taap.2005.01.061
Autor:
Celeste M. Nelson, Simone Bennett, Connie S. Chen, Derek C. Radisky, Davitte Khauv, Yohei Hirai, Evette S. Radisky, Mina J. Bissell
We have shown that branching morphogenesis of mammary ductal structures requires the action of the morphogen epimorphin/syntaxin-2. Epimorphin, originally identified as an extracellular molecule, is identical to syntaxin-2, an intracellular molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4f634e2ac25dd903c537e736ed3a85
https://europepmc.org/articles/PMC2652326/
https://europepmc.org/articles/PMC2652326/
Autor:
Jeffrey T. Henderson, Andrea W. Wong, Julia Perstin, Connie S. Chen, Michael J. Wiley, Thomas J. Preston, Crystal J. J. Lee, Peter G. Wells, Gordon P. McCallum
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 108(1)
In the developing embryo and fetus, endogenous or xenobiotic-enhanced formation of reactive oxygen species (ROS) like hydroxyl radicals may adversely alter development by oxidatively damaging cellular lipids, proteins and DNA, and/or by altering sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6d2e1829c538a4041524e1dd6412cb
https://pubmed.ncbi.nlm.nih.gov/19126598
https://pubmed.ncbi.nlm.nih.gov/19126598
Autor:
Peter G. Wells, Connie S. Chen
Publikováno v:
Annals of the New York Academy of Sciences. 1031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c311fe0fb96ab61ba37c479bf9eccdb8
https://pubmed.ncbi.nlm.nih.gov/15753179
https://pubmed.ncbi.nlm.nih.gov/15753179
Autor:
Jordi Alcaraz, Celeste M. Nelson, Connie S. Chen, Cyrus M. Ghajar, Joni D. Mott, Mina J. Bissell, Hui Zhang, Hidetoshi Mori, Alvin Lo, Motoharu Seiki, Jamie L. Bascom, Jamie L. Inman
Publikováno v:
Journal of Cell Science. 126:e1-e1
Epithelial cell invasion through the extracellular matrix (ECM) is a crucial step in branching morphogenesis. The mechanisms by which the mammary epithelium integrates cues from the ECM with intracellular signaling in order to coordinate invasion thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f12a197193ef30965d937c88b861a15
https://doi.org/10.1242/jcs.130054
https://doi.org/10.1242/jcs.130054
Autor:
Connie S. Chen, Peter G. Wells
Publikováno v:
Carcinogenesis; Jul2006, Vol. 27 Issue 7, p1358-1368, 11p
Autor:
Peter G. Wells, Gordon P. McCallum, Connie S. Chen, Jeffrey T. Henderson, Crystal J. J. Lee, Julia Perstin, Thomas J. Preston, Michael J. Wiley, Andrea W. Wong
Publikováno v:
Toxicological Sciences; Mar2009, Vol. 108 Issue 1, p4-4, 1p