Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Connie Sánchez"'
Autor:
Jessica A. Waller, Sara Holm Nygaard, Yan Li, Kristian Gaarn du Jardin, Joseph A. Tamm, Aicha Abdourahman, Betina Elfving, Alan L. Pehrson, Connie Sánchez, Rasmus Wernersson
Publikováno v:
BMC Neuroscience, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background The identification of biomarkers that predict susceptibility to major depressive disorder and treatment response to antidepressants is a major challenge. Vortioxetine is a novel multimodal antidepressant that possesses pro-cogniti
Externí odkaz:
https://doaj.org/article/6ad74c4aa9b34a46b8e8a08350e7b99c
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 15150-15171 (2015)
Neuropsychiatric symptoms of systemic lupus erythematosus (NP-SLE) have been understudied compared to end-organ failure and peripheral pathology. Neuropsychiatric symptoms, particularly affective and cognitive indications, may be among the earliest m
Externí odkaz:
https://doaj.org/article/b24fd89d3e8d42da90e4a6471beb508f
Autor:
Shreaya Chakroborty, Thomas R. Geisbush, Elena Dale, Alan L. Pehrson, Connie Sánchez, Anthony R. West
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Prefrontal-subcortical circuits support executive functions which often become dysfunctional in psychiatric disorders. Vortioxetine is a multimodal antidepressant that is currently used in the clinic to treat major depressive disorder. Mechanisms of
Externí odkaz:
https://doaj.org/article/bfcb3e7c436444749047a169969dd0b9
Publikováno v:
Schweimer, J V, Brouard, J T, Li, Y, Sánchez, C & Sharp, T 2022, ' In vivo electrophysiological study of the targeting of 5-HT 3 receptor-expressing cortical interneurons by the multimodal antidepressant, vortioxetine ', European Journal of Neuroscience, vol. 55, no. 6, pp. 1409-1423 . https://doi.org/10.1111/ejn.15623
The antidepressant vortioxetine has high affinity for the ionotropic 5-HT3 receptor (5-HT3R) as well as other targets including the 5-HT transporter. The procognitive effects of vortioxetine have been linked to altered excitatory:inhibitory balance i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0261f6a121c6f2b22d8b484eafd93b2f
https://pure.au.dk/portal/da/publications/in-vivo-electrophysiological-study-of-the-targeting-of-5ht3-receptorexpressing-cortical-interneurons-by-the-multimodal-antidepressant-vortioxetine(92a8cd9a-8cef-4a35-a287-fe378370f4f8).html
https://pure.au.dk/portal/da/publications/in-vivo-electrophysiological-study-of-the-targeting-of-5ht3-receptorexpressing-cortical-interneurons-by-the-multimodal-antidepressant-vortioxetine(92a8cd9a-8cef-4a35-a287-fe378370f4f8).html
Autor:
Nasriya A, Witt, Benita, Lee, Kaylee, Ghent, Wynne Q, Zhang, Alan L, Pehrson, Connie, Sánchez, Georgianna G, Gould
Publikováno v:
ACS chemical neuroscience. 10(10)
Vortioxetine is a multimodal antidepressant with agonist activity at serotonin (5-HT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8287f9779be878a9f01d296866034084
https://pubmed.ncbi.nlm.nih.gov/31468969
https://pubmed.ncbi.nlm.nih.gov/31468969
Autor:
Mehnaz I. Ferdousi, Patricia Calcagno, Connie Sanchez, Karen L. Smith, John P. Kelly, Michelle Roche, David P. Finn
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
IntroductionChronic pain is often associated with comorbid anxiety and cognitive dysfunction, negatively affecting therapeutic outcomes. The influence of genetic background on such interactions is poorly understood. The stress-hyperresponsive Wistar
Externí odkaz:
https://doaj.org/article/10e5361d06f441ba8957d01cacccae79
Autor:
Alex Nackenoff, Linda Simmler, Nicole Baganz, Krista Paffenroth, Gregg Stanwood, Alan Pehrson, Connie Sánchez, Randy Blakely
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e043cb0ada5d873d12520b51532edffc
https://doi.org/10.1096/fasebj.29.1_supplement.932.5
https://doi.org/10.1096/fasebj.29.1_supplement.932.5
Publikováno v:
Neuropharmacology. 89
Since poor circadian synchrony and cognitive dysfunction have been linked to affective disorders, antidepressants that target key 5-HT (serotonin) receptor subtypes involved in circadian rhythm and cognitive regulation may have therapeutic utility. V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba5957e871326dccef0dd822871dab98
https://pubmed.ncbi.nlm.nih.gov/25446573
https://pubmed.ncbi.nlm.nih.gov/25446573
Autor:
Kristian Gaarn du Jardin, Nico Liebenberg, Heidi Kaastrup Müller, Connie Sánchez, Gregers Wegener, Betina Elfving
Publikováno v:
du Jardin, K G, Liebenberg, N, Müller, H K, Sánchez, C, Wegener, G & Elfving, B 2013, ' A single dose of vortioxetine or ketamine, but not fluoxetine, increases transcript levels of genes involved in neuroplasticity in the rat prefrontal cortex ', San Diego, United States, 09/11/2013-13/11/2013, .
Aarhus University
Aarhus University
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::47aaef7fcffe4a1b0e759345dcc01c6e
https://pure.au.dk/portal/da/publications/a-single-dose-of-vortioxetine-or-ketamine-but-not-fluoxetine-increases-transcript-levels-of-genes-involved-in-neuroplasticity-in-the-rat-prefrontal-cortex(9bcbd2d2-fcb3-4dc9-9d65-a5cc8b58c2dd).html
https://pure.au.dk/portal/da/publications/a-single-dose-of-vortioxetine-or-ketamine-but-not-fluoxetine-increases-transcript-levels-of-genes-involved-in-neuroplasticity-in-the-rat-prefrontal-cortex(9bcbd2d2-fcb3-4dc9-9d65-a5cc8b58c2dd).html
Autor:
Jane B. Acri, Franco Borsini, Jack Bergman, Christian Chiamulera, Sandra Comer, Colin T. Dourish, Tracie J. Gardner, Jon E. Grant, Jason Halford, Margaret Haney, Christian A. Heidbreder, George F. Koob, Therese Kosten, Thomas Kosten, Hilary J. Little, Athina Markou, Robert A. McArthur, David J. McCann, David L. McKinzie, Marc N. Potenza, Beatriz A. Rocha, Edward M. Sellers, Beatrice Setnik, Megan J. Shram, Roger D. Spealman, Frank Vocci, Robert J. West, John P.H. Wilding, Wendol A. Williams, Catharine A. Winstanley, Paul Willner, Jennifer A. Bartz, Linda Brady, Joseph D. Buxbaum, Brian Campbell, Phillip Chappell, John F. Cryan, Timothy G. Dinan, Scott M. Doran, Jamie Driscoll, Haim Einat, Oliver Freudenreich, Jane E. Gartlon, Mark A. Geyer, Eric Hollander, Andrew Holmes, Daphna Joel, Declan N.C. Jones, Thomas S. Kilduff, Charles H. Large, Atul R. Mahableshwarkar, Joseph P. McEvoy, Klaus A. Miczek, Mark J. Millan, Arpi Minassian, Daniele Ouellet, William Perry, John J. Renger, Robert H. Ring, Connie Sánchez, Rudy Schreiber, Patricia Seymour, Holly Soares, Thomas Steckler, Murray B. Stein, Dan J. Stein, Rosemary Tannock, Fred Turek, Paul Wang, Thomas Wessel, Lois Winsky, Larry J. Young
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad8a9bda4c8a957323232d87fc7606d1
https://doi.org/10.1016/b978-0-12-373861-5.00035-7
https://doi.org/10.1016/b978-0-12-373861-5.00035-7