Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Connie P. Matthews"'
Autor:
Nancy H. Colburn, Matthew R. Young, George R. Beck, Christine M. Perella, Alyson R. Baker, Alysia M. Birkholz, Connie P. Matthews
Supplementary Figures 1-3, Tables 1-2 from Dominant-Negative Activator Protein 1 (TAM67) Targets Cyclooxygenase-2 and Osteopontin under Conditions in which It Specifically Inhibits Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b16780135abd4693f9fd3e88675bd67d
https://doi.org/10.1158/0008-5472.22365828
https://doi.org/10.1158/0008-5472.22365828
Autor:
Nancy H. Colburn, Matthew R. Young, George R. Beck, Christine M. Perella, Alyson R. Baker, Alysia M. Birkholz, Connie P. Matthews
Activation of activator protein 1 (AP-1) and nuclear factor κB (NFκB)–dependent transcription is required for tumor promotion in cell culture models and transgenic mice. Dominant-negative c-Jun (TAM67) blocks AP-1 activation by dimerizing with Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47217f02b39d0d866db4ba50c2f351b3
https://doi.org/10.1158/0008-5472.c.6494877.v1
https://doi.org/10.1158/0008-5472.c.6494877.v1
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. 223:316-321
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05b19a2cd238683b5a0a98d8d8977858
https://doi.org/10.1111/j.1525-1373.2000.22345.x
https://doi.org/10.1111/j.1525-1373.2000.22345.x
Publikováno v:
Current Cancer Drug Targets. 7:317-324
The transcription factor activator protein 1 (AP-1) plays a pivotal role in tumorigenesis. AP-1 activity is increased in multiple human tumor types. Inhibitors of AP-1 have been shown to block tumor promotion, transformation, progression and invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aa197110f0d8ddb676107ca672cb4f
https://doi.org/10.2174/156800907780809723
https://doi.org/10.2174/156800907780809723
Autor:
Qing Wang, Timothy Clair, Connie P. Matthews, Hsin-Sheng Yang, Alyson R. Baker, Tse-Hua Tan, Chou-Chi H. Li, Nancy H. Colburn
Publikováno v:
Molecular and Cellular Biology. 26:1297-1306
Programmed cell death 4 (Pdcd4) suppresses neoplastic transformation by inhibiting the activation of c-Jun and consequently AP-1-dependent transcription. We report that Pdcd4 blocks c-Jun activation by inhibiting the expression of mitogen-activated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10444b64e67cf6749ad1a5db3f701849
https://doi.org/10.1128/mcb.26.4.1297-1306.2006
https://doi.org/10.1128/mcb.26.4.1297-1306.2006
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1520:187-194
Mouse Boo/Diva is an ovary-specific member of the Bcl-2 family identified through homology with the avian cell death antagonist NR13. We identified a human orthologue of Boo/Diva, which is highly conserved between mouse and human and related to avian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add43828ac50b6fa69b2856f67f68c92
https://doi.org/10.1016/s0167-4781(01)00268-8
https://doi.org/10.1016/s0167-4781(01)00268-8
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. 223:316-321
To identify chromosomal regions that may include the loci of abnormally expressed cellular genes and may be specifically altered depending on the histological subtype of the tumor, we studied primary cervical carcinoma using CGH and HPV genotyping. E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415a50553302f84f16ee0e556f46fa68
https://doi.org/10.1046/j.1525-1373.2000.22345.x
https://doi.org/10.1046/j.1525-1373.2000.22345.x
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(50)
Previous studies have shown that a dominant negative form of c-Jun (TAM67) suppresses mouse skin carcinogenesis both in vitro and in vivo . The current study identifies Sulfiredoxin (Srx) as a unique target of activator protein-1 (AP-1) activation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced18feb82846c39910123e1f7c0076a
https://pubmed.ncbi.nlm.nih.gov/19057013
https://pubmed.ncbi.nlm.nih.gov/19057013
Autor:
Alyson R. Baker, Christine M. Perella, George R. Beck, Connie P. Matthews, Matthew R. Young, Nancy H. Colburn, Alysia M. Birkholz
Publikováno v:
Cancer research. 67(6)
Activation of activator protein 1 (AP-1) and nuclear factor κB (NFκB)–dependent transcription is required for tumor promotion in cell culture models and transgenic mice. Dominant-negative c-Jun (TAM67) blocks AP-1 activation by dimerizing with Ju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a7a329ff5067c8bac88d8b1563c1be
https://pubmed.ncbi.nlm.nih.gov/17363560
https://pubmed.ncbi.nlm.nih.gov/17363560
Publikováno v:
Oncogene. 20(34)
To analyse FHIT transcription patterns in cervical cancer, a series of primary cervical tumors and normal control samples were studied using RT-PCR. Full length and truncated FHIT transcripts were detectable in all samples tested. Interestingly, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e74617ee84eb0b91eb5b4b15964d9e2
https://pubmed.ncbi.nlm.nih.gov/11498789
https://pubmed.ncbi.nlm.nih.gov/11498789