Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Connie M Ross"'
Autor:
Gabriel Foley, Ariane Mora, Connie M Ross, Scott Bottoms, Leander Sützl, Marnie L Lamprecht, Julian Zaugg, Alexandra Essebier, Brad Balderson, Rhys Newell, Raine E S Thomson, Bostjan Kobe, Ross T Barnard, Luke Guddat, Gerhard Schenk, Jörg Carsten, Yosephine Gumulya, Burkhard Rost, Dietmar Haltrich, Volker Sieber, Elizabeth M J Gillam, Mikael Bodén
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 10, p e1010633 (2022)
Ancestral sequence reconstruction is a technique that is gaining widespread use in molecular evolution studies and protein engineering. Accurate reconstruction requires the ability to handle appropriately large numbers of sequences, as well as insert
Externí odkaz:
https://doaj.org/article/6706c45e0af54c36a70246e9e790f19a
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618257
Analyzing the natural evolution of proteins by ancestral sequence reconstruction (ASR) can provide valuable information about the changes in sequence and structure that drive the development of novel protein functions. However, ASR has also been used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a963d355c9bd17527489f4ee9162935a
https://doi.org/10.1007/978-1-0716-1826-4_6
https://doi.org/10.1007/978-1-0716-1826-4_6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2397
Analyzing the natural evolution of proteins by ancestral sequence reconstruction (ASR) can provide valuable information about the changes in sequence and structure that drive the development of novel protein functions. However, ASR has also been used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef2884700b7c311f21f7481bc65eb6c7
https://pubmed.ncbi.nlm.nih.gov/34813061
https://pubmed.ncbi.nlm.nih.gov/34813061
Autor:
Scott Bottoms, Marnie L. Lamprecht, Luke W. Guddat, Jörg Carsten, Volker Sieber, Ariane Mora, Alexandra Essebier, Bostjan Kobe, Brad Balderson, Connie M. Ross, Raine E. S. Thomson, Elizabeth M. J. Gillam, Leander Sützl, Rhys Newell, Burkhard Rost, G. Foley, Julian Zaugg, Ross Barnard, Dietmar Haltrich, Mikael Bodén, Gerhard Schenk, Yosephine Gumulya
Ancestral sequence reconstruction is a technique that is gaining widespread use in molecular evolution studies and protein engineering. Accurate reconstruction requires the ability to handle appropriately large numbers of sequences, as well as insert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::201cef017b0beb84465a5ba6f740229a
https://doi.org/10.1101/2019.12.30.891457
https://doi.org/10.1101/2019.12.30.891457
Publikováno v:
Life Science Alliance
This study provides a detailed molecular mechanism for caspase-11 activation within the non-canonical inflammasome, giving new insight into host defence against cytosolic bacterial infection.
Caspase-11 is a cytosolic sensor and protease that dr
Caspase-11 is a cytosolic sensor and protease that dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::951fd3c5e86b6f8798ed4c44ce2237f4
https://eprints.whiterose.ac.uk/156010/1/e201800237.full.pdf
https://eprints.whiterose.ac.uk/156010/1/e201800237.full.pdf
Publikováno v:
Methods in Molecular Biology ISBN: 9781493975679
The caspase-1 protease is a core component of multiprotein inflammasome complexes, which play a critical role in regulating the secretion of mature, bioactive pro-inflammatory cytokines interleukin (IL)-1β and IL-18. The activity of caspase-1 is oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fc2aaed77f5440532d1715028a0e4a0
https://doi.org/10.1007/978-1-4939-7568-6_14
https://doi.org/10.1007/978-1-4939-7568-6_14
Autor:
Dave Boucher, Rebecca C. Coll, Alpha S. Yap, Damien Bierschenk, Jelena S. Bezbradica, Kaiwen W. Chen, Guillermo A. Gomez, Mercedes Monteleone, Kate Schroder, Katryn J. Stacey, Connie M. Ross, Jessica L. Teo, Caroline L. Holley
Publikováno v:
The Journal of Experimental Medicine
The inflammasome generates caspase-1 p20/p10, presumed to be the active protease. Boucher et al. demonstrate that the inflammasome contains an active caspase-1 species, p33/p10, and functions as a holoenzyme. Further caspase-1 self-processing generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1219ffca512429332158e54cdb0341
https://hdl.handle.net/11541.2/131290
https://hdl.handle.net/11541.2/131290